Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anette ten Haaf"'
Autor:
Nic Waddell, Anette Ten Haaf, Anna Marsh, Julie Johnson, Logan C Walker, kConfab Investigators, Milena Gongora, Melissa Brown, Piyush Grover, Mark Girolami, Sean Grimmond, Georgia Chenevix-Trench, Amanda B Spurdle
Publikováno v:
PLoS Genetics, Vol 4, Iss 5, p e1000080 (2008)
The functional consequences of missense variants in disease genes are difficult to predict. We assessed if gene expression profiles could distinguish between BRCA1 or BRCA2 pathogenic truncating and missense mutation carriers and familial breast canc
Externí odkaz:
https://doaj.org/article/e56535396f4e411b95f0a7a2e40c20c6
Publikováno v:
Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen. 108:528-538
The Act on the Reform of the Market for Medicinal Products (AMNOG) became effective in Germany on January 1, 2011. Since then, the assessment of the added benefit of new drugs versus a therapeutic standard on the basis of dossiers submitted by pharma
Autor:
Ruth Knüchel, Caroline Heymann, Edgar Dahl, Anette ten Haaf, Laura Franken, Sonja von Serenyi, Joep P.J. de Hoon, Bernhard Lüscher, Jürgen Veeck, Christian Cornelissen
Publikováno v:
Scopus-Elsevier
Epigenetics, 6(4), 466-478. Landes Bioscience
Epigenetics, 6(4), 466-478. Landes Bioscience
Recently, DNA methylation has been suggested as a potential mechanism involved in the transcriptional regulation of SHH gene expression in cancer. However, detailed analyses on the underlying transcriptional mechanisms of SHH expression have not been
Autor:
Anette Ten Haaf, kConFab Investigators, Amanda B. Spurdle, Logan C. Walker, Sean M. Grimmond, Nic Waddell
Publikováno v:
Breast Cancer Research and Treatment. 112:229-236
Germline mutations in BRCA1 or BRCA2 confer an increased lifetime risk of developing breast or ovarian cancer, but variable penetrance suggests that cancer susceptibility is influenced in part by modifier genes. Microarray expression profiling was co
Publikováno v:
Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen. 108(8-9)
The Act on the Reform of the Market for Medicinal Products (AMNOG) became effective in Germany on January 1, 2011. Since then, the assessment of the added benefit of new drugs versus a therapeutic standard on the basis of dossiers submitted by pharma
Autor:
Nuran Bektas, Inge Losen, Arndt Hartmann, Ruth Knüchel, Elfriede Christel Arweiler, Anette ten Haaf, Sonja von Serenyi, Edgar Dahl
Publikováno v:
BMC Cancer
BMC cancer 9(298), (2009). doi:10.1186/1471-2407-9-298
BMC Cancer, Vol 9, Iss 1, p 298 (2009)
BMC cancer 9(298), (2009). doi:10.1186/1471-2407-9-298
BMC Cancer, Vol 9, Iss 1, p 298 (2009)
Background The transcription factor GLI1, a member of the GLI subfamily of Krüppel-like zinc finger proteins is involved in signal transduction within the hedgehog pathway. Aberrant hedgehog signalling has been implicated in the development of diffe
Autor:
Andreas Thess, Hans Dr Kiefer, Stefan Barth, Nuran Bektas, Hannah Jörißen, Anette ten Haaf, Stefano Di Fiore, Edgar Dahl, Torsten Klockenbring, Arndt Hartmann
Publikováno v:
BMC cancer 9(200), (2009). doi:10.1186/1471-2407-9-200
BMC Cancer
BMC Cancer, Vol 9, Iss 1, p 200 (2009)
BMC Cancer
BMC Cancer, Vol 9, Iss 1, p 200 (2009)
Background RAI3 is an orphan G-protein coupled receptor (GPCR) that has been associated with malignancy and may play a role in the proliferation of breast cancer cells. Although its exact function in normal and malignant cells remains unclear and evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3718ab3918c42d85a215e889116306
Autor:
Amanda B. Spurdle, Milena Gongora, Piyush Grover, Georgia Chenevix-Trench, Logan C. Walker, Nic Waddell, Julie Johnson, Anna Marsh, Anette Ten Haaf, Melissa A. Brown, Mark Girolami, Sean M. Grimmond, kConFab Investigators
Publikováno v:
PLoS Genetics, Vol 4, Iss 5, p e1000080 (2008)
PLoS Genetics
PLoS Genetics
The functional consequences of missense variants in disease genes are difficult to predict. We assessed if gene expression profiles could distinguish between BRCA1 or BRCA2 pathogenic truncating and missense mutation carriers and familial breast canc
Autor:
Arndt Hartmann, Ruth Knüchel, Peter J. Wild, Juliane Lüscher-Firzlaff, Nuran Bektas, Anette ten Haaf, Edgar Dahl, Jürgen Veeck
Publikováno v:
BMC cancer 8, 42 (2008). doi:10.1186/1471-2407-8-42
BMC Cancer, Vol 8, Iss 1, p 42 (2008)
BMC Cancer
BMC Cancer, Vol 8, Iss 1, p 42 (2008)
BMC Cancer
BackgroundFOXM1 regulates expression of cell cycle related genes that are essential for progression into DNA replication and mitosis. Consistent with its role in proliferation, elevated expression of FOXM1 has been reported in a variety of human tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1846be29c889d33b57740612d0425495
https://publications.rwth-aachen.de/record/164067
https://publications.rwth-aachen.de/record/164067