Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Anette Veringa"'
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Akademický článek
Inflammation altered correlation between CYP2C19 genotype and CYP2C19 activity in patients receiving voriconazole
Autor: Sylvia D. Klomp, Anette Veringa, Jan‐Willem C. Alffenaar, Mark G. J. deBoer, Lambert F. R. Span, Henk‐Jan Guchelaar, Jesse J. Swen
Publikováno v: Clinical and Translational Science, Vol 17, Iss 7, Pp n/a-n/a (2024)
Abstract Voriconazole is the cornerstone of the treatment and prevention of fungal infections. While there is a good correlation between CYP2C19 genotype and voriconazole exposure during prophylactic treatment, no correlation was found in patients wi
Externí odkaz: https://doaj.org/article/6d2407fc26434dd2b9215c84b25c3c29
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2
Voriconazole exposure is influenced by inflammation: A population pharmacokinetic model
Autor: D. Abraham van den Born, Anne-Grete Märtson, Anette Veringa, Nieko C. Punt, Tjip S. van der Werf, Jan-Willem C. Alffenaar, Marieke G.G. Sturkenboom, Daan J. Touw
Publikováno v: International journal of antimicrobial agents, 61:106750. Elsevier Bedrijfsinformatie b.v.
BACKGROUND: Voriconazole is an antifungal drug used for the treatment of invasive fungal infections. Due to highly variable drug exposure, therapeutic drug monitoring (TDM) has been recommended. TDM may be helpful to accurately predict exposure but c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1264e17e5b81f7ec3a4c17377ae5c3
https://research.rug.nl/en/publications/506ac619-c1c0-4565-b1fc-7460c23742fd
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4
Caspofungin Weight-Based Dosing Supported by a Population Pharmacokinetic Model in Critically Ill Patients
Autor: Jan G. Zijlstra, Anne-Grete Märtson, Michael Neely, Jos G. W. Kosterink, Tjip S. van der Werf, Albertus Beishuizen, Jan-Willem C. Alffenaar, Kim C M van der Elst, Anette Veringa
Publikováno v: Antimicrobial Agents and Chemotherapy, 64(9):ARTN e00905-20. AMER SOC MICROBIOLOGY
Antimicrobial Agents and Chemotherapy
The objective of this study was to develop a population pharmacokinetic model and to determine a dosing regimen for caspofungin in critically ill patients. Nine blood samples were drawn per dosing occasion. Fifteen patients with (suspected) invasive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a877418808747ef542bf40fe512db0f8
https://hdl.handle.net/11370/6c344d14-db20-4051-acef-898b548164c6
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5
Invasive Candidiasis in the Elderly
Autor: Bart G. J. Dekkers, Deborah Marriott, Andrew J. McLachlan, K. C. M. van der Elst, Jan-Willem C. Alffenaar, J M Boonstra, F F Doukas, Anette Veringa
Publikováno v: Drugs & Aging
Drugs & Aging, 35(9), 781-789. ADIS INT LTD
Candida infections in the elderly are an important and expanding clinical problem, with significantly higher mortality in this group than in younger patients. The increasing problem of invasive Candida infections may be related to higher prevalence o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9095e569fc0cdf41f3ac03572f43e964
https://doi.org/10.1007/s40266-018-0576-9
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6
Bioavailability of voriconazole in hospitalised patients
Autor: Tjip S. van der Werf, Sanne Geling, Jos G. W. Kosterink, Jan G. Zijlstra, Lambert F.R. Span, Karin M. Vermeulen, Anette Veringa, Jan-Willem C. Alffenaar
Publikováno v: International journal of antimicrobial agents, 49(2), 243-246. Elsevier Bedrijfsinformatie b.v.
An important element in antimicrobial stewardship programmes is early switch from intravenous (i.v.) to oral antimicrobial treatment, especially for highly bioavailable drugs. The antifungal agent voriconazole is available both in i.v. and oral formu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904ad2a45079c561585a31b432b81598
https://doi.org/10.1016/j.ijantimicag.2016.10.010
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7
Voriconazole metabolism is influenced by severe inflammation
Autor: Tjip S. van der Werf, Mendy ter Avest, Jos G. W. Kosterink, Jan G. Zijlstra, Lambert F.R. Span, Edwin R. van den Heuvel, Daan J Touw, Jan-Willem C. Alffenaar, Anette Veringa
Publikováno v: Journal of Antimicrobial Chemotherapy, 72, 261-267
Journal of Antimicrobial Chemotherapy, 72, 1, pp. 261-267
Journal of Antimicrobial Chemotherapy, 72(1), 261-267. Oxford University Press
Background: During an infection or inflammation, several drug-metabolizing enzymes in the liver are downregulated, including cytochrome P450 iso-enzymes. Since voriconazole is extensively metabolized by cytochrome P450 iso-enzymes, the metabolism of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b734114355030a9f5049e38e29caeaf
https://doi.org/10.1093/jac/dkw349
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8
Posaconazole trough concentrations are not influenced by inflammation: a prospective study
Autor: Anne-Grete Märtson, Martijn Bakker, Jan-Willem C. Alffenaar, Tjip S. van der Werf, Anette Veringa, Edwin R. van den Heuvel, Lambert F.R. Span, Daan J Touw
Publikováno v: International Journal of Antimicrobial Agents, 53(3), 325-329. Elsevier
International journal of antimicrobial agents, 53(3), 325-329. Elsevier Bedrijfsinformatie b.v.
BACKGROUND: During inflammation several cytochrome P450 enzymes are down-regulated. Recently it was shown that voriconazole metabolism is reduced during inflammation. Posaconazole, another triazole with broad-spectrum antifungal activity, is only to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55849d4750b6102e4a2f9a9a4e8a8ed3
https://research.tue.nl/nl/publications/2c2081c7-9ba7-4515-90b1-4b9b88ddc030
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9
Combined Impact of Inflammation and Pharmacogenomic Variants on Voriconazole Trough Concentrations: A Meta-Analysis of Individual Data
Autor: Anette Veringa, Jan-Willem C. Alffenaar, Takafumi Naito, Françoise Stanke-Labesque, Fabien Lamoureux, Takahiro Yamada, Elodie Gautier-Veyret, Xavier Fonrose, Léa Bolcato, Charles Khouri
Publikováno v: Journal of Clinical Medicine, Vol 10, Iss 2089, p 2089 (2021)
Journal of Clinical Medicine
Volume 10
Issue 10
Journal of Clinical Medicine, 10(10):2089. MDPI AG
Few studies have simultaneously investigated the impact of inflammation and genetic polymorphisms of cytochromes P450 2C19 and 3A4 on voriconazole trough concentrations. We aimed to define the respective impact of inflammation and genetic polymorphis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04447137d9a2a15dfd9f09ca83bddef
https://doi.org/10.3390/jcm10102089
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10
LC-MS/MS for Therapeutic Drug Monitoring of anti-infective drugs
Autor: Charles A. Peloquin, Jason A. Roberts, Marieke G G Sturkenboom, Remco A. Koster, Jan-Willem C. Alffenaar, Daan J Touw, Bart G. J. Dekkers, Anette Veringa
Publikováno v: TrAC-Trends in Analytical Chemistry, 84(Part B), 34-40. ELSEVIER SCI LTD
Therapeutic drug monitoring (TDM) is a tool used to integrate pharmacokinetic and pharmacodynamic knowledge to optimise and personalize drug therapy. TDM is of specific interest for anti-infectives: to assure adequate drug exposure and reduce adverse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0a47b1a1b6714369f6cb9884762733
https://hdl.handle.net/11370/61500f98-8a82-40b0-9efb-b8bf5daec5d2
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