Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Anette Preiss"'
Publikováno v:
Cells, Vol 13, Iss 7, p 576 (2024)
Blood cells in Drosophila serve primarily innate immune responses. Various stressors influence blood cell homeostasis regarding both numbers and the proportion of blood cell types. The principle molecular mechanisms governing hematopoiesis are conser
Externí odkaz:
https://doaj.org/article/e1fd3c4944bc4f37a55079230916b087
Publikováno v:
Hereditas, Vol 156, Iss 1, Pp 1-9 (2019)
Abstract Background In Drosophila, the development of the fly eye involves the activity of several, interconnected pathways that first define the presumptive eye field within the eye anlagen, followed by establishment of the dorso-ventral boundary, a
Externí odkaz:
https://doaj.org/article/5b12b1f915cf49879f63320bdbe8223c
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12336 (2022)
The primary role of Notch is to specify cellular identities, whereby the cells respond to amazingly small changes in Notch signalling activity. Hence, dosage of Notch components is crucial to regulation. Central to Notch signal transduction are CSL p
Externí odkaz:
https://doaj.org/article/0f3c758616184a409e2a400168584622
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 8, Pp 2477-2487 (2019)
Members of the Protein Kinase D (PKD) family are involved in numerous cellular processes in mammals, including cell survival after oxidative stress, polarized transport of Golgi vesicles, as well as cell migration and invasion. PKD proteins belong to
Externí odkaz:
https://doaj.org/article/efc1879b72c840bca03b0594df0cb91c
Publikováno v:
Hereditas, Vol 155, Iss 1, Pp 1-12 (2018)
Abstract Background DNA damage generally results in the activation of ATM/ATR kinases and the downstream checkpoint kinases Chk1/Chk2. In Drosophila melanogaster, the ATR homologue meiotic 41 (mei-41) is pivotal to DNA damage repair and cell cycle ch
Externí odkaz:
https://doaj.org/article/e44b77925e894b168c5295516fd30df0
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1672 (2021)
The Notch signaling pathway is pivotal to cellular differentiation. Activation of this pathway involves proteolysis of the Notch receptor and the release of the biologically active Notch intracellular domain, acting as a transcriptional co-activator
Externí odkaz:
https://doaj.org/article/ff86cd4a37364b038af7dcab4331854b
Publikováno v:
Data in Brief, Vol 5, Iss C, Pp 852-863 (2015)
In Drosophila, Notch and EGFR signalling pathways are closely intertwined. Their relationship is mostly antagonistic, and may in part be based on the phosphorylation of the Notch signal transducer Suppressor of Hairless [Su(H)] by MAPK. Su(H) is a tr
Externí odkaz:
https://doaj.org/article/d5555da0a634469cb2fe2e881cff46ec
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193956 (2018)
Throughout the animal kingdom, the Notch signalling pathway allows cells to acquire diversified cell fates. Notch signals are translated into activation of Notch target genes by CSL transcription factors. In the absence of Notch signals, CSL together
Externí odkaz:
https://doaj.org/article/40c3818865ca4fac82f023fbe0247456
Autor:
Heiko Praxenthaler, Anja C Nagel, Adriana Schulz, Mirjam Zimmermann, Markus Meier, Hannes Schmid, Anette Preiss, Dieter Maier
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006774 (2017)
Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-bind
Externí odkaz:
https://doaj.org/article/40ddec43b486410eadf0c3ddf0121cd4
Autor:
Zhenyu Yuan, Heiko Praxenthaler, Nassif Tabaja, Rubben Torella, Anette Preiss, Dieter Maier, Rhett A Kovall
Publikováno v:
PLoS Biology, Vol 14, Iss 7, p e1002509 (2016)
Notch is a conserved signaling pathway that specifies cell fates in metazoans. Receptor-ligand interactions induce changes in gene expression, which is regulated by the transcription factor CBF1/Su(H)/Lag-1 (CSL). CSL interacts with coregulators to r
Externí odkaz:
https://doaj.org/article/6d4b97dd248d4e17887d370eb00fe4aa