Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anette Hübner"'
Publikováno v:
Journal of Virology
Profound type I interferon (IFN-I)-dependent attrition of memory CD8 and CD4 T cells occurs early during many infections. It is dramatic at 2 to 4 days following lymphocytic choriomeningitis virus (LCMV) infection of mice and can be elicited by the I
Publikováno v:
Molecular and Cellular Biology. 30:98-105
Bcl2-modifying factor (Bmf) is a member of the BH3-only group of proapoptotic proteins. To test the role of Bmf in vivo, we constructed mice with a series of mutated Bmf alleles that disrupt Bmf expression, prevent Bmf phosphorylation by the c-Jun NH
Autor:
Anette Hübner, Kevan M. Shokat, Chao Zhang, Richard A. Flavell, Roger J. Davis, Juan-Jose Ventura
Publikováno v:
Molecular Cell. 21(5):701-710
Exposure of primary murine embryonic fibroblasts to tumor necrosis factor (TNF) causes biphasic activation of the c-Jun NH(2)-terminal kinase (JNK) signaling pathway. The early phase (30 min) of the response to TNF is a large and transient increase i
Publikováno v:
Applied and Environmental Microbiology. 64:2086-2093
Chlorinated phenols and phenoxyacetates are a group of chemical compounds which have been used extensively as pesticides, wood preservatives, and herbicides in the agricultural industry. They are a major group of recalcitrant environmental pollutants
Publikováno v:
Developmental Cell. 11(6):752-754
Tumors can become dependent upon signaling by oncogenes. In a recent issue of Cancer Cell, Sharma et al. (2006b) reported that "oncogene addiction" may be mediated by differential rates of signal attenuation of proapoptotic and prosurvival pathways.
Autor:
Dale L. Greiner, Charles L. Sawyers, Richard A. Flavell, David J. Mulholland, Maria Karasarides, Cathy Tournier, Claire L. Standen, Tamera Barrett, Julie Cavanagh-Kyros, Anette Hübner, Hongbo Chi, Roger J. Davis, Hong Wu
Publikováno v:
The Journal of urology. 189(5)
The c-Jun NH 2 -terminal kinase (JNK) signal transduction pathway is implicated in cancer, but the role of JNK in tumorigenesis is poorly understood. Here, we demonstrate that the JNK signaling pathway reduces the development of invasive adenocarcino
Publikováno v:
Journal of Molecular Biology. 223:595-600
The in vitro fidelity of reverse transcriptase from human immunodeficiency virus type I (HIV-1 RT) upon copying an RNA template was measured using the φXam16 reversion assay. A φX174 sequence harboring the amber 16 codon was cloned into a transcrip
Publikováno v:
Molecular cell. 30(4)
The pro-apoptotic BH3-only protein Bim is established to be an important mediator of signaling pathways that induce cell death. Multi-site phosphorylation of Bim by several members of the MAP kinase group is implicated as a regulatory mechanism that
Autor:
Craig S. Brinkworth, Wen-Hai Chou, Anette Hübner, Stephen M. Hedrick, Kevan M. Shokat, Jennifer Paulson, Carol D. Katayama, Dan Wang, Roger J. Davis, Robert O. Messing, Jasmina J. Allen, Alma L. Burlingame, Manqing Li
Publikováno v:
Nature methods. 4(6)
The ubiquitous nature of protein phosphorylation makes it challenging to map kinase-substrate relationships, which is a necessary step toward defining signaling network architecture. To trace the activity of individual kinases, we developed a semisyn
The luxS gene product is an integral component of LuxS/autoinducer-2 (AI-2) quorum-sensing systems in bacteria. A putative luxS gene was expressed at comparable levels by Borrelia burgdorferi strain 297 cultivated either in vitro or in dialysis membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447721da5888653892196c7af88d3fcc
https://europepmc.org/articles/PMC153291/
https://europepmc.org/articles/PMC153291/