Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anetta Marcinek"'
Autor:
Siret Tahk, Binje Vick, Björn Hiller, Saskia Schmitt, Anetta Marcinek, Enrico D. Perini, Alexandra Leutbecher, Christian Augsberger, Anna Reischer, Benjamin Tast, Andreas Humpe, Irmela Jeremias, Marion Subklewe, Nadja C. Fenn, Karl-Peter Hopfner
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Background Acute myeloid leukaemia (AML) stem cells (LSCs) cause disease relapse. The CD47 “don’t eat me signal” is upregulated on LSCs and contributes to immune evasion by inhibiting phagocytosis through interacting with myeloid-speci
Externí odkaz:
https://doaj.org/article/283f6b159bc043879ea7f65025d1d5d9
Autor:
Maryam Ghalandary, Yuqiao Gao, Diana Amend, Ginte Kutkaite, Binje Vick, Karsten Spiekermann, Maja Rothenberg-Thurley, Klaus H. Metzeler, Anetta Marcinek, Marion Subklewe, Michael P. Menden, Vindi Jurinovic, Ehsan Bahrami, Irmela Jeremias
Publikováno v:
Blood 141, 955-960 (2023)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e777957f2127dbfb7a5c772674add21
https://doi.org/10.1182/blood.2022016411
https://doi.org/10.1182/blood.2022016411
Autor:
Anetta Marcinek, Bettina Brauchle, Lisa Rohrbacher, Gerulf Hänel, Nora Philipp, Florian Märkl, Thaddäus Strzalkowski, Sonja M. Lacher, Dragica Udiljak, Karsten Spiekermann, Sebastian Theurich, Sebastian Kobold, Roman Kischel, John R. James, Veit L. Bücklein, Marion Subklewe
Publikováno v:
Cancer Immunology, Immunotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e89147d3fb33bc7a716fe89d6309ea
https://doi.org/10.1007/s00262-023-03457-9
https://doi.org/10.1007/s00262-023-03457-9
Autor:
Anetta Marcinek, Bettina Brauchle, Lisa Rohrbacher, Gerulf Hänel, Nora Philipp, Florian Märkl, Thaddäus Strzalkowski, Sonja M. Lacher, Dragica Udiljak, Karsten Spiekermann, Sebastian Theurich, Sebastian Kobold, Roman Kischel, John R. James, Veit L. Bücklein, Marion Subklewe
Publikováno v:
Cancer Immunology, Immunotherapy.
Bispecific T-cell engager (BiTE®) molecules recruit T cells to cancer cells through CD3ε binding, independently of T-cell receptor (TCR) specificity. Whereas physiological T-cell activation is dependent on signal 1 (TCR engagement) and signal 2 (co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d261a13bce3e2164141a44c5580a8a48
https://doi.org/10.1007/s00262-023-03439-x
https://doi.org/10.1007/s00262-023-03439-x
Autor:
Monika Sponheimer, Gerulf Hänel, Lisa Rohrbacher, Nora Philipp, Daniel Nixdorf, Anetta Marcinek, Christian Wichmann, Andreas Humpe Med, Shyra Gardai, Daniel Diolaiti, Veit Leonhardt Bücklein, Marion Subklewe
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2e1e39129c60141a2f836eea2680d1b
https://doi.org/10.1136/jitc-2022-sitc2022.0281
https://doi.org/10.1136/jitc-2022-sitc2022.0281
Autor:
Lisa Rohrbacher, Daniel Nixdorf, Helena Stadler, Bettina Brauchle, Florian Märkl, Nora Philipp, Gerulf Hänel, Anetta Marcinek, Maryam Kazerani, Rebecca L. Goldstein, Michael von Bergwelt, Sebastian Kobold, Veit L. Bücklein, Tara Arvedson, Marion Subklewe
Publikováno v:
Cancer Research. 83:894-894
Translation of the success of bispecific T cell engagers (BiTE®) and CAR T cells from B-cell to myeloid malignancies has been challenging. Identifying suitable target antigens in myeloid malignancies has been hampered by expected on-target-off leuke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70462d16cbe2029d949d38027f2c3f2d
https://doi.org/10.1158/1538-7445.am2023-894
https://doi.org/10.1158/1538-7445.am2023-894
Autor:
Lisa Rohrbacher, Daniel Nixdorf, Helena Stadler, Bettina Brauchle, Florian Märkl, Nora Phillip, Gerulf Hänel, Anetta Marcinek, Maryam Kazerani, Rebecca Goldstein, Michael von Bergwelt, Sebastian Kobold, Veit L Buecklein, Tara Chapman-Arvedson, Marion Subklewe
Publikováno v:
Blood. 140:10233-10234
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b4946762c7e23c56b70c1c45c61f660
https://doi.org/10.1182/blood-2022-158452
https://doi.org/10.1182/blood-2022-158452
Autor:
Nora Philipp, Maryam Kazerani, Alyssa Nicholls, Binje Vick, Jan Wulf, Tobias Straub, Michaela Scheurer, Amelie Muth, Gerulf Hänel, Daniel Nixdorf, Monika Sponheimer, Malte Ohlmeyer, Sonja M. Lacher, Bettina Brauchle, Anetta Marcinek, Lisa Rohrbacher, Alexandra Leutbecher, Kai Rejeski, Oliver Weigert, Michael von Bergwelt-Baildon, Sebastian Theurich, Roman Kischel, Irmela Jeremias, Veit Bücklein, Marion Subklewe
Publikováno v:
Blood 140, 1104-1118 (2022)
T-cell–recruiting bispecific molecule therapy has yielded promising results in patients with hematologic malignancies; however, resistance and subsequent relapse remains a major challenge. T-cell exhaustion induced by persistent antigen stimulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0efbd8fee53c3a987bf6a5a848ae63
https://pubmed.ncbi.nlm.nih.gov/36074532
https://pubmed.ncbi.nlm.nih.gov/36074532
Autor:
Marion Subklewe, Bettina Brauchle, Christina Krupka, Nadja C. Fenn, Ana Ogrinc Wagner, Felicitas Rataj, Katrin Deiser, Sebastian Kobold, Karsten Spiekermann, Monika Herrmann, Anetta Marcinek, Klaus H. Metzeler, Ralph Mocikat, Karl-Peter Hopfner
Publikováno v:
Blood. 132:2484-2494
The CD33-targeting bispecific T-cell engager (BiTE) AMG 330 proved to be highly efficient in mediating cytolysis of acute myeloid leukemia (AML) cells in vitro and in mouse models. Yet, T-cell activation is correlated with upregulation of programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c329830d711044d269b00cc7f3cd7a09
https://doi.org/10.1182/blood-2018-05-849802
https://doi.org/10.1182/blood-2018-05-849802
Autor:
Nora Zieger, Anne-Sophie Neumann, Marion Subklewe, Alexandra Leutbecher, Vesna Pulko, Christina Claus, Anetta Marcinek, Pablo Umana, Veit Buecklein, Christian Klein, Gerulf Hänel
Publikováno v:
Blood. 138:1178-1178
Bispecific antibodies represent a promising treatment option for acute myeloid leukemia (AML). We have recently described a novel T-cell bispecific antibody (TCB) targeting the intracellular tumor antigen Wilms tumor 1 (WT1) in the context of HLA-A*0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::228b628f621c574f067ae67d9748091b
https://doi.org/10.1182/blood-2021-146762
https://doi.org/10.1182/blood-2021-146762