Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anett Stephan"'
Autor:
Simone Hahn-Löbmann, Anett Stephan, Steve Schulz, Tobias Schneider, Anton Shaverskyi, Daniel Tusé, Anatoli Giritch, Yuri Gleba
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Recently, several plant-made recombinant proteins received favorable regulatory review as food antibacterials in the United States through the Generally Recognized As Safe (GRAS) regulatory procedure, and applications for others are pending. These fo
Externí odkaz:
https://doaj.org/article/0ff5b39c71fc449e9c1c401a5c452e75
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 95 (2017)
Colicins are natural non-antibiotic bacterial proteins with a narrow spectrum but an extremely high antibacterial activity. These proteins are promising food additives for the control of major pathogenic Shiga toxin-producing E. coli serovars in meat
Externí odkaz:
https://doaj.org/article/ed5be1b760fe467b89a47991f4586d2c
Autor:
Tobias Schneider, Anton Shaverskyi, Anett Stephan, Simone Hahn-Löbmann, Anatoli Giritch, Yuri Gleba, Daniel Tuse, Steve Schulz
Publikováno v:
Frontiers in Plant Science
Frontiers in Plant Science, Vol 10 (2019)
Frontiers in Plant Science, Vol 10 (2019)
Recently, several plant-made recombinant proteins received favorable regulatory review as food antibacterials in the United States through the Generally Recognized As Safe (GRAS) regulatory procedure, and applications for others are pending. These fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba444fbdb1b759972b918ae16baac2b4
http://europepmc.org/articles/PMC6465592
http://europepmc.org/articles/PMC6465592
Autor:
Tobias Schneider, Anett Stephan, Steve Schulz, Marcel Naumann, Simone Hahn-Löbmann, Martin Kleinschmidt, Daniel Tuse, Anatoli Giritch, Yuri Gleba
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Salmonella enterica causes an estimated 1 million illnesses in the United States each year, resulting in 19,000 hospitalizations and 380 deaths, and is one of the four major global causes of diarrhoeal diseases. No effective treatments are available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eef11c78ef89c51c4cf2d74d475b73a
https://publica.fraunhofer.de/handle/publica/256683
https://publica.fraunhofer.de/handle/publica/256683
Autor:
Stephan Schilling, Birgit Koch, Michael Wermann, Alex von Bohlen, Hans-Ulrich Demuth, Holger Cynis, Anett Stephan
Publikováno v:
FEBS Journal. 276:6522-6536
Glutaminyl cyclases (QCs) catalyze the formation of pyroglutamate residues at the N-terminus of several peptides and proteins from plants and animals. Recently, isoenzymes of mammalian QCs have been identified. In order to gain further insight into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1f78ff344f3025a179d7f5b57e44771
https://doi.org/10.1111/j.1742-4658.2009.07337.x
https://doi.org/10.1111/j.1742-4658.2009.07337.x
Autor:
Birgit Koch, Astrid Kehlen, Stephan Schilling, Jens-Ulrich Rahfeld, Michael Wermann, Hans-Ulrich Demuth, Holger Cynis, Anett Stephan
Publikováno v:
Journal of Molecular Biology. 379:966-980
Mammalian glutaminyl cyclase isoenzymes (isoQCs) were identified. The analysis of the primary structure of human isoQC (h-isoQC) revealed conservation of the zinc-binding motif of the human QC (hQC). In contrast to hQC, h-isoQC carries an N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989a513b4502c8f8ddc4b919430363ce
https://doi.org/10.1016/j.jmb.2008.03.078
https://doi.org/10.1016/j.jmb.2008.03.078
Autor:
Anatoli Giritch, Yuri Gleba, Daniel Tuse, Anett Stephan, Chad H. Stahl, Ulrike Bettmann, Franziska Jarczowski, Simone Hahn, Anne-Katrin Paschke, Luisa Bortesi, Steve Schulz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(40)
Enterohemorrhagic Escherichia coli (EHEC) is one of the leading causes of bacterial enteric infections worldwide, causing ∼100,000 illnesses, 3,000 hospitalizations, and 90 deaths annually in the United States alone. These illnesses have been linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38829c36b93c1e6a9705980ad6870ea
https://pubmed.ncbi.nlm.nih.gov/26401021
https://pubmed.ncbi.nlm.nih.gov/26401021
Autor:
Sabine Berg, Stephan Schilling, Alexander P. Osmand, Stephan von Hörsten, Alexander Waniek, Stephanie Kohlmann, Anne-Christine Plank, Sigrid Graubner, Birgit Koch, Christoph Bäuscher, Ernst-Joachim Freyse, Reinhard Sedlmeier, Astrid Kehlen, Hans-Ulrich Demuth, Steffen Roßner, Holger Cynis, Torsten Hoffmann, Andreas Becker, Rico Eichentopf, Anett Stephan
Publikováno v:
Biological chemistry. 397(1)
Secretory peptides and proteins are frequently modified by pyroglutamic acid (pE, pGlu) at their N-terminus. This modification is catalyzed by the glutaminyl cyclases QC and isoQC. Here, we decipher the roles of the isoenzymes by characterization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594f84fb026d0df46e5f7c6ab8011b62
https://pubmed.ncbi.nlm.nih.gov/26351917
https://pubmed.ncbi.nlm.nih.gov/26351917
Autor:
Isabel Hesse, Daniel Friedrich, Ernst-Joachim Freyse, Monique Haegele, Stephan Schilling, Ulrich Heiser, Anke Müller, Daniela Trautwein, Torsten Hoffmann, Kathrin Gans, Paul H.A. Quax, Reinhard Sedlmeier, Astrid Kehlen, Sigrid Graubner, Rico Eichentopf, Margreet R. de Vries, Wolfgang Jagla, Sabine Berg, Martin Kleinschmidt, Raik Wolf, Hans-Ulrich Demuth, Michael Wermann, Jens-Ulrich Rahfeld, Franziska Seifert, Ulrich Wollert, Holger Cynis, Anett Stephan
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, 3(9), 545-558
EMBO Molecular Medicine, 3(9), 545-558
Acute and chronic inflammatory disorders are characterized by detrimental cytokine and chemokine expression. Frequently, the chemotactic activity of cytokines depends on a modified N-terminus of the polypeptide. Among those, the N-terminus of monocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ef56b3bed3bb6eabff1dcf614a02b4
https://hdl.handle.net/1887/118371
https://hdl.handle.net/1887/118371
Autor:
Anett, Stephan, Michael, Wermann, Alex, von Bohlen, Birgit, Koch, Holger, Cynis, Hans-Ulrich, Demuth, Stephan, Schilling
Publikováno v:
The FEBS journal. 276(22)
Glutaminyl cyclases (QCs) catalyze the formation of pyroglutamate residues at the N-terminus of several peptides and proteins from plants and animals. Recently, isoenzymes of mammalian QCs have been identified. In order to gain further insight into t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bcfb81fa75955d1d28ffdf9f89d3f58
https://pubmed.ncbi.nlm.nih.gov/19804409
https://pubmed.ncbi.nlm.nih.gov/19804409