Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anett Ritter"'
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e400 (2007)
Polymerization and organization of actin filaments into complex superstructures is indispensable for structure and function of neuronal networks. We here report that knock down of the F-actin-binding protein Abp1, which is important for endocytosis a
Externí odkaz:
https://doaj.org/article/24354466781642fab9706d4b6326b624
Autor:
Bernd Voedisch, Thomas Jostock, Holger Laux, Tatjana Rauschert, Sandro Nuciforo, Anett Ritter, Mevion Oertli, Sabine Geisse, Axel Schulze
Publikováno v:
Biotechnology and Bioengineering. 114:701-704
Recombinant CHO (Chinese hamster ovary) cell lines producing therapeutic proteins often lose their production capability during long-term cultivation. To ensure that CHO production cell lines can be up-scaled to high-volume bioreactors, labor intensi
Autor:
Genevieve Kuntzelmann, Bernd Voedisch, Panagiotis Mantas, Barbara Brannetti, Tatjana Rauschert, Nadine Lageyre, Sabine Geisse, Daniel Piehlmaier, Anett Ritter, Mevion Oertli, Holger Laux, Thomas Jostock
Publikováno v:
Biotechnology and Bioengineering. 113:2433-2442
Recently, we reported that the loss of a telomeric region of chromosome 8 in Chinese Hamster Ovary (CHO) cells correlates with higher recombinant productivities. New cell lines lacking this region, called CHO-C8DEL, showed several advantages during c
Autor:
Holger Laux, Thomas Jostock, Anett Ritter, Joerg Schmidt, Burkhard Wilms, Mara Fornaro, Sandrine Romand
Publikováno v:
Biotechnology and Bioengineering. 113:1094-1101
Chinese Hamster Ovary (CHO) cells are widely used for the large-scale production of recombinant biopharmaceuticals. However, attempts to express IGF-1 (a mutated human Insulin-like growth factor 1 Ea peptide (hIGF-1Ea mut)) in CHO cells resulted in p
Autor:
Anett Ritter, Thomas Jostock, Sabine Geisse, Burkhard Wilms, Holger Laux, Johannes Wienberg, Bernd Voedisch
Publikováno v:
Biotechnology and Bioengineering. 113:1084-1093
Chinese Hamster Ovary (CHO) cells are widely used for large scale production of recombinant biopharmaceuticals. Although these cells have been extensively used, a demand to further increase the performance, for example, to facilitate the process of c
Autor:
Anett, Ritter, Sandro, Nuciforo, Axel, Schulze, Mevion, Oertli, Tatjana, Rauschert, Bernd, Voedisch, Sabine, Geisse, Thomas, Jostock, Holger, Laux
Publikováno v:
Biotechnology and bioengineering. 114(3)
Recombinant CHO (Chinese hamster ovary) cell lines producing therapeutic proteins often lose their production capability during long-term cultivation. To ensure that CHO production cell lines can be up-scaled to high-volume bioreactors, labor intensi
Autor:
Anett, Ritter, Tatjana, Rauschert, Mevion, Oertli, Daniel, Piehlmaier, Panagiotis, Mantas, Genevieve, Kuntzelmann, Nadine, Lageyre, Barbara, Brannetti, Bernd, Voedisch, Sabine, Geisse, Thomas, Jostock, Holger, Laux
Publikováno v:
Biotechnology and bioengineering. 113(11)
Recently, we reported that the loss of a telomeric region of chromosome 8 in Chinese Hamster Ovary (CHO) cells correlates with higher recombinant productivities. New cell lines lacking this region, called CHO-C8DEL, showed several advantages during c
Publikováno v:
BMC Proceedings
Background Chinese hamster ovary (CHO) cells are the most widely used host for large scale production of recombinant therapeutic proteins. A combination of several gene editing approaches applied to Novartis proprietary CHO cell line resulted in a su
Autor:
Sven Rothemund, Klemens Rottner, Anett Ritter, Mirko Himmel, Björg V. Pauling, Alexandre R. Gingras, Wolfgang H. Ziegler
Publikováno v:
Journal of Biological Chemistry. 284:13832-13842
In cell-extracellular matrix junctions (focal adhesions), the cytoskeletal protein talin is central to the connection of integrins to the actin cytoskeleton. Talin is thought to mediate this connection via its two integrin, (at least) three actin, an
Autor:
Sandrine, Romand, Thomas, Jostock, Mara, Fornaro, Joerg, Schmidt, Anett, Ritter, Burkhard, Wilms, Holger, Laux
Publikováno v:
Biotechnology and bioengineering. 113(5)
Chinese Hamster Ovary (CHO) cells are widely used for the large-scale production of recombinant biopharmaceuticals. However, attempts to express IGF-1 (a mutated human Insulin-like growth factor 1 Ea peptide (hIGF-1Ea mut)) in CHO cells resulted in p