DMPC Phospholipid Bilayer as a Potential Interface for Human Cystatin C Oligomerization: Analysis of Protein-Liposome Interactions Using NMR Spectroscopy

Autor: Przemyslaw Jurczak, Kosma Szutkowski, Slawomir Lach, Stefan Jurga, Paulina Czaplewska, Aneta Szymanska, Igor Zhukov

Publikováno v: Membranes, Vol 11, Iss 1, p 13 (2020)

Studies revolving around mechanisms responsible for the development of amyloid-based diseases lay the foundations for the recognition of molecular targets of future to-be-developed treatments. However, the vast number of peptides and proteins known t

Externí odkaz: https://doaj.org/article/f67e9152700b4d55ab4a6ec4620c0d98

Human cysteine cathepsins are not reliable markers of infection by Pseudomonas aeruginosa in cystic fibrosis.

Autor: Clément Naudin, Alix Joulin-Giet, Gérard Couetdic, Patrick Plésiat, Aneta Szymanska, Emilia Gorna, Francis Gauthier, Franciszek Kasprzykowski, Fabien Lecaille, Gilles Lalmanach

Publikováno v: PLoS ONE, Vol 6, Iss 9, p e25577 (2011)

Cysteine cathepsins have emerged as new players in inflammatory lung disorders. Their activities are dramatically increased in the sputum of cystic fibrosis (CF) patients, suggesting that they are involved in the pathophysiology of CF. We have charac

Externí odkaz: https://doaj.org/article/5a17670a2c5d47e4a1e8bb6f0f3b4555

Diversity and Inclusion in the Workplace: Employee Perception and Implications for Internal Brand Management

Autor: Aneta Szymanska, Denis Aldighieri

Publikováno v: International Conference on Advances in Business and Law (ICABL); Vol. 1 No. 1 (2017): 1st International Conference on Advances In Business, Management, and Law (ICABML-2017); 368-388

The study explores the issues connected with diversity and inclusion in the workplace and their application in internal branding. The authors draw attention to the depth of the problematics and identify the gaps in research results concerning the mea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2990eb432da74f604fb3daf5e98d84e5
https://publications.ud.ac.ae/index.php/ICABML-CP/article/view/32

Binding Epitopes and Interaction Structure of the Neuroprotective Protease Inhibitor Cystatin C with β-Amyloid Revealed by Proteolytic Excision Mass Spectrometry and Molecular Docking Simulation

Autor: Aneta S Kolodziejczyk, Aneta Szymanska, Zbigniew Grzonka, Michael Przybylski, Gabriela Paraschiv, Sylwia Rodziewicz-Motowidło, Paulina Juszczyk

Publikováno v: Journal of Medicinal Chemistry. 52:2420-2428

Human cystatin C (HCC) is a protease inhibitor with a propensity to form beta-amyloid (Abeta)-like fibrils and to coassociate with amyloidogenic proteins. Recently, a specific interaction between HCC and Abeta has been found. Here, we report the iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9717913838f26b5db90cc8ec11b18cc
https://doi.org/10.1021/jm801115e

The Role of the Disulfide Bridge in the Copper (II) Binding by the Cyclic His4-Peptide

Autor: Aleksandra Pieniężna, Weronika Witak, Aneta Szymańska, Justyna Brasuń

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 12, p 6458 (2021)

In this paper, we present studies on the influence of the disulfide bridge on the copper (II) ions’ binding abilities by the cyclic His4-peptide. The studied ligand HKHPHRHC-S-S-C consists of nine amino acids. The cyclic structure was obtained thro

Externí odkaz: https://doaj.org/article/5cac347750754ad7a522d3e0a1d3816d