Effect of Escitalopram on the Number of DCX-Positive Cells and NMUR2 Receptor Expression in the Rat Hippocampus under the Condition of NPSR Receptor Blockade

Autor: Aneta Piwowarczyk-Nowak, Artur Pałasz, Aleksandra Suszka-Świtek, Iwona Błaszczyk, Katarzyna Bogus, Barbara Łasut-Szyszka, Marek Krzystanek, John J. Worthington

Publikováno v: Pharmaceuticals, Vol 15, Iss 5, p 631 (2022)

Background: Neuropeptide S (NPS) is a multifunctional regulatory factor that exhibits a potent anxiolytic activity in animal models. However, there are no reports dealing with the potential molecular interactions between the activity of selective ser

Externí odkaz: https://doaj.org/article/221881a91500498097a209f70a2eaa3c

Modulatory effect of long-term treatment with escitalopram and clonazepam on the expression of anxiety-related neuropeptides:neuromedin U, neuropeptide S and their receptors in the rat brain

Autor: Aneta Piwowarczyk-Nowak, Artur Pałasz, Katarzyna Bogus, Marek Krzystanek, Iwona Błaszczyk, John J. Worthington, Aniela Grajoszek

BACKGROUND: Newly identified multifunctional peptidergic modulators of stress responses: neuromedin U (NMU) and neuropeptide S (NPS) are involved in the wide spectrum of brain functions. However, there are no reports dealing with potential molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46fb6439d71e9a319a6a0272504c3967
https://doi.org/10.1007/s11033-022-07578-9

Longitudinal Shifts of Solid Tumor and Liquid Biopsy Sequencing Concordance in Metastatic Breast Cancer

Autor: Minetta C. Liu, Matthew MacKay, Matthew Kase, Aneta Piwowarczyk, Christine Lo, Jeff Schaeffer, Justin D. Finkle, Christopher E. Mason, Nike Beaubier, Kimberly L. Blackwell, Ben Ho Park

Publikováno v: JCO precision oncology. 6(1)

PURPOSE Tissue-based next-generation sequencing (NGS) in metastatic breast cancer (mBC) is limited by the inability to noninvasively track tumor evolution. Cell-free DNA (cfDNA) NGS has made sequential testing feasible; however, the relationship betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc590eed5a186aa9560aad7496027350
https://pubmed.ncbi.nlm.nih.gov/35721584

Escitalopram as a modulator of proopiomelanocortin, kisspeptin, Kiss1R and MCHR1 gene expressions in the male rat brain

Autor: Artur Pałasz, Aneta Piwowarczyk-Nowak, John J. Worthington, Aleksandra Suszka-Świtek, Łukasz Filipczyk, Ryszard Wiaderkiewicz, Katarzyna Bogus, Marek Krzystanek, Alessandra Della Vecchia, Kinga Mordecka-Chamera, Itiana Castro Menezes

Publikováno v: Molecular Biology Reports

Neuropeptides are important, multifunctional regulatory factors of the nervous system, being considered as a novel, atypical sites of antidepressants action. It has already been proven that some of them, such as selective serotonin reuptake inhibitor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7163538819f5d579dd651d6166b87a3
https://pubmed.ncbi.nlm.nih.gov/32914264

Effect of long-term treatment with classical neuroleptics on NPQ/spexin, kisspeptin and POMC mRNA expression in the male rat amygdala

Autor: Marek Krzystanek, Aneta Piwowarczyk-Nowak, John J. Worthington, Ewa Rojczyk, Marcelina Pałka, Itiana Castro Menezes, Ryszard Wiaderkiewicz, Łukasz Filipczyk, Artur Pałasz

Publikováno v: Pałasz, A, Pałka, M, Filipczyk, Ł, Menezes, I C, Rojczyk, E, Worthington, J J, Piwowarczyk-Nowak, A, Krzystanek, M & Wiaderkiewicz, R 2018, ' Effect of long-term treatment with classical neuroleptics on NPQ/spexin, kisspeptin and POMC mRNA expression in the male rat amygdala ', Journal of Neural transmission, vol. 125, no. 7, pp. 1099-1105 . https://doi.org/10.1007/s00702-018-1868-2
Journal of Neural Transmission

Neuroleptics modulate the expression level of some regulatory neuropeptides in the brain. However, if these therapeutics influence the peptidergic circuits in the amygdala remains unclear. This study specifies the impact profile of the classical anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c40cbbdb438d002cd5bfef73c467f8b
https://doi.org/10.1007/s00702-018-1868-2