Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aneta M. Dobosz"'
Autor:
Aneta M. Dobosz, Justyna Janikiewicz, Ewelina Krogulec, Anna Dziewulska, Anna Ajduk, Marcin Szpila, Hanna Nieznańska, Andrzej A. Szczepankiewicz, Dorota Wypych, Agnieszka Dobrzyn
Publikováno v:
Molecular Metabolism, Vol 67, Iss , Pp 101659- (2023)
Abnormalities that characterize the pathophysiology of type 2 diabetes (T2D) include deficiencies of β-cells and the expansion of α-cells in pancreatic islets, manifested by lower insulin release and glucagon oversecretion. The molecular mechanisms
Externí odkaz:
https://doaj.org/article/93b47b0cfaee40919c316cd1cf33440e
Autor:
Piotr Szczepaniak, Mateusz Siedlinski, Diana Hodorowicz-Zaniewska, Ryszard Nosalski, Tomasz P. Mikolajczyk, Aneta M. Dobosz, Anna Dikalova, Sergey Dikalov, Joanna Streb, Katarzyna Gara, Pawel Basta, Jaroslaw Krolczyk, Joanna Sulicka-Grodzicka, Ewelina Jozefczuk, Anna Dziewulska, Blessy Saju, Iwona Laksa, Wei Chen, John Dormer, Maciej Tomaszewski, Pasquale Maffia, Marta Czesnikiewicz-Guzik, Filippo Crea, Agnieszka Dobrzyn, Javid Moslehi, Tomasz Grodzicki, David G. Harrison, Tomasz J. Guzik
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Cardiovascular disease is the major cause of morbidity and mortality in breast cancer survivors. Chemotherapy contributes to this risk. We aimed to define the mechanisms of long-term vascular dysfunction caused by neoadjuvant chemotherapy (NACT) and
Externí odkaz:
https://doaj.org/article/4b3b8954d7104657a53492a95dc463f4
Autor:
Anna Dziewulska, James M. Ntambi, Pawel Dobrzyn, Katarzyna Kolczynska, Agnieszka Smolinska, Agnieszka Dobrzyn, Aneta M Dobosz
Publikováno v:
Journal of Cellular Physiology. 235:1129-1140
Stearoyl-CoA desaturase (SCD) is a rate-limiting enzyme that catalyzes the synthesis of monounsaturated fatty acids. It plays an important role in regulating skeletal muscle metabolism. Lack of the SCD1 gene increases the rate of fatty acid β-oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fa956caea9a4758a75725ad0715c37
https://doi.org/10.1002/jcp.29026
https://doi.org/10.1002/jcp.29026
Publikováno v:
Postępy Biochemii. 64:157-165
Type 2 diabetes (T2D) is a complex disorder that is caused by a combination of genetic, epigenetic, and environmental factors. β-cell failure and insulin resistance in peripheral tissues that are induced by lipid overload are main hallmarks of T2D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab5e2961c966c4130dce4015260ab9d3
https://doi.org/10.18388/pb.2018_126
https://doi.org/10.18388/pb.2018_126
Autor:
Anna Dziewulska, Agnieszka Dobrzyn, Justyna Janikiewicz, Aneta M Dobosz, Pawel Dobrzyn, Wojciech M. Kwiatek, Anna M. Borkowska, Ewelina Lipiec
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6844, p 6844 (2020)
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6844, p 6844 (2020)
Metabolic stress, such as lipotoxicity, affects the DNA methylation profile in pancreatic &beta
cells and thus contributes to &beta
cell failure and the progression of type 2 diabetes (T2D). Stearoyl-CoA desaturase 1 (SCD1) is a rate-limiti
cells and thus contributes to &beta
cell failure and the progression of type 2 diabetes (T2D). Stearoyl-CoA desaturase 1 (SCD1) is a rate-limiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615a70a5c95e0b69d9e4d47576270801
https://pubmed.ncbi.nlm.nih.gov/32961871
https://pubmed.ncbi.nlm.nih.gov/32961871
Autor:
Justyna Janikiewicz, Pawel Dobrzyn, Agnieszka Dobrzyn, Anna Filip, Ewelina Krogulec, Aneta M Dobosz, Zuzanna Tracz-Gaszewska
Sphingolipids belong to a relatively minor class of lipid species in mammalian cells, but they have gained considerable attention recently because of emerging evidence that links them with lipotoxicity and a reduction of insulin sensitivity. This cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::142e08fe6f6c06ed9c51a5d47591bc5f
https://doi.org/10.1016/b978-0-12-819404-1.00019-1
https://doi.org/10.1016/b978-0-12-819404-1.00019-1
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bad9573109e890e5b3403854cdc1bf79
https://doi.org/10.1096/fasebj.2020.34.s1.09112
https://doi.org/10.1096/fasebj.2020.34.s1.09112
Autor:
Anna M. Borkowska, Justyna Janikiewicz, Aneta M Dobosz, Agnieszka Dobrzyn, Wojciech M. Kwiatek
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::587fa870dfe7c298a8cc992a32e65f5a
https://doi.org/10.1096/fasebj.2020.34.s1.09301
https://doi.org/10.1096/fasebj.2020.34.s1.09301
Publikováno v:
Postepy biochemii. 64(2)
Type 2 diabetes (T2D) is a complex disorder that is caused by a combination of genetic, epigenetic, and environmental factors. β-cell failure and insulin resistance in peripheral tissues that are induced by lipid overload are main hallmarks of T2D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2c829a1790351089110adac22b019ea
https://pubmed.ncbi.nlm.nih.gov/30656898
https://pubmed.ncbi.nlm.nih.gov/30656898