Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Anelia Ts. Mavrova"'
Autor:
Neda O. Anastassova, Anelia Ts. Mavrova, Denitsa Y. Yancheva, Magdalena S. Kondeva-Burdina, Virginia I. Tzankova, Simeon S. Stoyanov, Boris L. Shivachev, Rositsa P. Nikolova
Publikováno v:
Arabian Journal of Chemistry, Vol 11, Iss 3, Pp 353-369 (2018)
A new method for the synthesis of 1,3-disubstituted benzimidazole derivatives was developed using aza-Michael addition. The target compounds were synthesized in good yields and purity and tested on isolated hepatocytes for their toxicity and antioxid
Externí odkaz:
https://doaj.org/article/b79a079cee824126ad5c93fcbcb3f653
Autor:
Maya Guncheva, Rumyana Tzoneva, Denitsa Yancheva, Anelia Ts. Mavrova, Kameliya Anichina, Galya Popova-Daskalova, Veselina Uzunova, Filip Fratev, Dimitar Vuchev, Maria Argirova
In the present study, fifteen benzimidazolyl-2-hydrazones 7a-7o of fluoro-, hydroxy- and methoxy-substituted benzaldehydes and 1,3-benzodioxole-5-carbaldehyde were synthesized and their structure was identified by IR, NMR, and elemental analysis. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da033c09b6496fce7c2216ab0f13000e
Autor:
Emilia Naydenova, Denitsa Yancheva, Diana Wesselinova, Anelia Ts. Mavrova, Miroslav Rangelov, Stefan Dimov
Publikováno v:
Anti-cancer agents in medicinal chemistry. 22(6)
Aims: The aim of the current study was to develop and explore a series of new cytotoxic agents based on the conjugation between the thieno[2,3-d]pyrimidine moiety and a second pharmacophore at the C2 or N3 position. Background: As the thieno[2,3-d]py
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfbb199c0f2777eb43843a54f5f173fe
https://pubmed.ncbi.nlm.nih.gov/34315388
https://pubmed.ncbi.nlm.nih.gov/34315388
Publikováno v:
Anti-cancer agents in medicinal chemistry. 21(11)
Aims: The purpose was the synthesis of some new thienopyrimidines derivative of 1,3-disubstituted benzimidazoles and the evaluation of their cytotoxicity towards MDA-MB-231 and MCF-7 cell lines as well 3T3 cells. Background: An overexpression or muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d719595f5280cb4b291eb12ec986ab3e
https://pubmed.ncbi.nlm.nih.gov/32698751
https://pubmed.ncbi.nlm.nih.gov/32698751
Autor:
D. Yancheva, Vera Hadjimitova, Nadya Hristova-Avakumova, Anelia Ts. Mavrova, Magdalena Kondeva-Burdina, Neda Anastassova, Virginia Tzankova
Publikováno v:
Journal of Molecular Structure. 1165:162-176
New series of N,N′-disubstituted benzimidazole-2-thione were synthesized by introduction of hydrazone moiety in the side chains. The toxicological potential of studied compounds was evaluated by monitoring the cell viability and levels of lactate d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c276d55ddcbda8872986f1871a3d561e
https://doi.org/10.1016/j.molstruc.2018.03.119
https://doi.org/10.1016/j.molstruc.2018.03.119
Publikováno v:
Letters in Drug Design & Discovery. 15:887-894
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fedab78b6b03373552071d7838af35f1
https://doi.org/10.2174/1570180814666171027161555
https://doi.org/10.2174/1570180814666171027161555
Autor:
Rositsa P. Nikolova, Virginia Tzankova, Magdalena Kondeva-Burdina, Neda Anastassova, Boris Shivachev, Denitsa Yancheva, Anelia Ts. Mavrova, Simeon Stoyanov
Publikováno v:
Arabian Journal of Chemistry, Vol 11, Iss 3, Pp 353-369 (2018)
A new method for the synthesis of 1,3-disubstituted benzimidazole derivatives was developed using aza-Michael addition. The target compounds were synthesized in good yields and purity and tested on isolated hepatocytes for their toxicity and antioxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b25af8d1065e7c0d81f25a97146aaf
http://www.sciencedirect.com/science/article/pii/S1878535216302362
http://www.sciencedirect.com/science/article/pii/S1878535216302362
Publikováno v:
Journal of Molecular Structure. 1150:179-187
The morphology of the crystal structure of some antitrichinellosis active benzimidazole derivatives including (1 H -benzimidazol-2-ylthio)acetic acids, [1,3]thiazolo[3,2- a ]benzimidazol-3(2 H )-ones, 1 H -benzimidazol-2-ylthioacetylpiperazines and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4effc8b7eeb8f8ed8cf5249fda23ad71
https://doi.org/10.1016/j.molstruc.2017.08.073
https://doi.org/10.1016/j.molstruc.2017.08.073
Autor:
Stefan Dimov, Budimir S. Ilić, Anelia Ts. Mavrova, Andrija Smelcerovic, Denitsa Yancheva, Marija Miljkovic, Gordana Kocic, Katarina Tomovic, Milan Kojic
Publikováno v:
Archiv der PharmazieREFERENCES. 353(1)
A small library of benzo[4,5]thieno[2,3-d]pyrimidine phthalimide and amine derivatives was evaluated for inhibitory activity against dipeptidyl peptidase-4 (DPP-4). The phthalimide derivatives exhibited better activity than the amine precursors, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66227c4cfc7693cad8578b67906f1f6
https://pubmed.ncbi.nlm.nih.gov/31710123
https://pubmed.ncbi.nlm.nih.gov/31710123
Autor:
Andrija Smelcerovic, Anelia Ts. Mavrova, Milan Kojic, Zaklina Smelcerovic, Katarina Tomovic, Denitsa Yancheva, Budimir S. Ilić, Marija Miljkovic, Gordana Kocic
Publikováno v:
Chemico-biological interactions. 315
Multiple-targeting compounds might reduce complex polypharmacy of multifactorial diseases, such as diabetes, and contribute to the greater therapeutic success. Targeting reactive oxygen species-producing enzymes, as xanthine oxidase (XO), might suppr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12396bb34a96635fbfca566be7068a6b
https://pubmed.ncbi.nlm.nih.gov/31669219
https://pubmed.ncbi.nlm.nih.gov/31669219