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Non-Clinical In Vitro Evaluation of Antibiotic Resistance Gene-Free Plasmids Encoding Human or Murine IL-12 Intended for First-in-Human Clinical Study

Autor: Spela Kos, Masa Bosnjak, Tanja Jesenko, Bostjan Markelc, Urska Kamensek, Katarina Znidar, Urska Matkovic, Andrej Rencelj, Gregor Sersa, Rosana Hudej, Aneja Tuljak, Matjaz Peterka, Maja Cemazar

Publikováno v: Pharmaceutics, Vol 13, Iss 10, p 1739 (2021)

Interleukin 12 (IL-12) is a key cytokine that mediates antitumor activity of immune cells. To fulfill its clinical potential, the development is focused on localized delivery systems, such as gene electrotransfer, which can provide localized delivery

Externí odkaz: https://doaj.org/article/e0a9f59802f9407ca46068c68fbe54cd

Biosafety of biotechnologically important microalgae: intrinsic suicide switch implementation in cyanobacterium Synechocystis sp. PCC 6803

Autor: Helena Čelešnik, Anja Tanšek, Aneja Tahirović, Angelika Vižintin, Jernej Mustar, Vita Vidmar, Marko Dolinar

Publikováno v: Biology Open, Vol 5, Iss 4, Pp 519-528 (2016)

In recent years, photosynthetic autotrophic cyanobacteria have attracted interest for biotechnological applications for sustainable production of valuable metabolites. Although biosafety issues can have a great impact on public acceptance of cyanobac

Externí odkaz: https://doaj.org/article/c7c428ba16a24b509e6e9432926754e9

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Heat Shock Protein 27 (HSP27) as a Potential Prognostic Marker: Immunohistochemical Analysis of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma.

Autor: Ramalingam K; Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND., Chawla G; Oral Pathology, Surendera Dental College and Research Institute, Sriganganagar, IND., Puri A; Oral Pathology, Himachal Institute of Dental Sciences, Paonta Sahib, IND., Krishnan M; Oral and Maxillofacial Surgery, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, IND., Aneja T; Dentistry, Department of Medical Health and Family Welfare, Uttarakhand, IND., Gill K; Oral Pathology, Surendera Dental College and Research Institute, Sriganganagar, IND.

Publikováno v: Cureus [Cureus] 2022 Dec 27; Vol. 14 (12), pp. e33020. Date of Electronic Publication: 2022 Dec 27 (Print Publication: 2022).