Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Aneesha Dasgupta"'
Autor:
Rebecca E. Schmitt, Aneesha Dasgupta, Paige C. Arneson‐Wissink, Srijani Datta, Alexandra M. Ducharme, Jason D. Doles
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1424-1440 (2023)
Abstract Background Over the past decade, advances in sepsis identification and management have resulted in decreased sepsis mortality. This increase in survivorship has highlighted a new clinical obstacle: chronic critical illness (CCI), for which t
Externí odkaz:
https://doaj.org/article/f763139a496d4e0c8ec1783ce66e6e5c
Autor:
Daria Neyroud, Orlando Laitano, Aneesha Dasgupta, Christopher Lopez, Rebecca E. Schmitt, Jessica Z. Schneider, David W. Hammers, H. Lee Sweeney, Glenn A. Walter, Jason Doles, Sarah M. Judge, Andrew R. Judge
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigate the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting ind
Externí odkaz:
https://doaj.org/article/325bfe808b054fee84c0ec177166dbea
Autor:
Stefan Nicolau, Aneesha Dasgupta, Surendra Dasari, M. Cristine Charlesworth, Kenneth L. Johnson, Akhilesh Pandey, Jason D. Doles, Margherita Milone
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Acquired sporadic late onset nemaline myopathy (SLONM) and inherited nemaline myopathy (iNM) both feature accumulation of nemaline rods in muscle fibers. Unlike iNM, SLONM is amenable to therapy. The distinction between these disorders is th
Externí odkaz:
https://doaj.org/article/6acd5dccc2d54faeb9ba149869c3f6dd
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1351-1363 (2020)
Abstract Background Persistent loss of skeletal muscle mass and function as well as altered fat metabolism are frequently observed in severe sepsis survivors. Studies examining sepsis‐associated tissue dysfunction from the perspective of the tissue
Externí odkaz:
https://doaj.org/article/ee9c898a6d6344abad00dee7a294cebb
Autor:
Aneesha Dasgupta, Paige C. Arneson-Wissink, Rebecca E. Schmitt, Dong Seong Cho, Alexandra M. Ducharme, Tara L. Hogenson, Eugene W. Krueger, William R. Bamlet, Lizhi Zhang, Gina L. Razidlo, Martin E. Fernandez-Zapico, Jason D. Doles
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Approximately 80% of pancreatic cancer patients suffer from cachexia, and one-third die due to cachexia-related complications such as respiratory failure and cardiac arrest. Although there has been considerable research into cachexia mechanisms and i
Externí odkaz:
https://doaj.org/article/fd3089a0330d47c2a75cc830a73c9afa
Publikováno v:
BioTech, Vol 11, Iss 1, p 6 (2022)
The research and development of non-viral gene therapy has been extensive over the past decade and has received a big push thanks to the recent successful approval of non-viral nucleic acid therapy products. Despite these developments, nucleic acid t
Externí odkaz:
https://doaj.org/article/1ec080cd44d04264bb03a32e5ed60b71
Autor:
Richard S. Laschanzky, Lisa E. Humphrey, Jihyun Ma, Lynette M. Smith, Thomas J. Enke, Surendra K. Shukla, Aneesha Dasgupta, Pankaj K. Singh, Gillian M. Howell, Michael G. Brattain, Quan P. Ly, Adrian R. Black, Jennifer D. Black
Publikováno v:
Cancers, Vol 11, Iss 9, p 1327 (2019)
Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of
Externí odkaz:
https://doaj.org/article/9f404c78c65f4f78b7440ae7df640563
Autor:
Stefan Nicolau, Aneesha Dasgupta, Surendra Dasari, Cristine Charlesworth, Kenneth Johnson, Akhilesh Pandey, Jason Doles, Margherita Milone
Publikováno v:
Sunday, April 23.
Data from MUC1-Mediated Metabolic Alterations Regulate Response to Radiotherapy in Pancreatic Cancer
Autor:
Pankaj K. Singh, Chi Lin, Tadayoshi Bessho, Fang Yu, Shuo Wang, Sicong Li, Ryan J. King, Nina V. Chaika, Aneesha Dasgupta, Enza Vernucci, Gennifer D. Goode, Surendra K. Shukla, Jaime Abrego, Joshua Souchek, Venugopal Gunda
Purpose: MUC1, an oncogene overexpressed in multiple solid tumors, including pancreatic cancer, reduces overall survival and imparts resistance to radiation and chemotherapies. We previously identified that MUC1 facilitates growth-promoting metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a38913aee94df543f33836c0388a54
https://doi.org/10.1158/1078-0432.c.6526560.v1
https://doi.org/10.1158/1078-0432.c.6526560.v1
Autor:
Pankaj K. Singh, Chi Lin, Tadayoshi Bessho, Fang Yu, Shuo Wang, Sicong Li, Ryan J. King, Nina V. Chaika, Aneesha Dasgupta, Enza Vernucci, Gennifer D. Goode, Surendra K. Shukla, Jaime Abrego, Joshua Souchek, Venugopal Gunda
Figure S1. BrPA inhibits MUC1-mediated nucleotide metabolism. Figure S2. Immunohistochemical staining for MUC1 in tumor sections.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2244741d34c5642c77c072e2e5d68916
https://doi.org/10.1158/1078-0432.22467183.v1
https://doi.org/10.1158/1078-0432.22467183.v1