Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Anees Rahman"'
Autor:
Karthikeyan Subburayan, Faisal Thayyullathil, Siraj Pallichankandy, Anees Rahman Cheratta, Ameer Alakkal, Mehar Sultana, Nizar Drou, Muhammad Arshad, L. Palanikumar, Mazin Magzoub, Vivek M. Rangnekar, Sehamuddin Galadari
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Ferroptosis is a unique iron-dependent form of non-apoptotic cell death characterized by devastating lipid peroxidation. Whilst growing evidence suggests that ferroptosis is a type of autophagy-dependent cell death, the underlying molecular
Externí odkaz:
https://doaj.org/article/b042898b09fd4d3082a06ae086a75503
Autor:
Siraj Pallichankandy, Faisal Thayyullathil, Anees Rahman Cheratta, Karthikeyan Subburayan, Ameer Alakkal, Mehar Sultana, Nizar Drou, Muhammad Arshad, Saeed Tariq, Sehamuddin Galadari
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Oxeiptosis is a recently identified reactive oxygen species (ROS)-sensitive, caspase independent, non-inflammatory regulated cell death pathway. The activation of Kelch-like ECH-associated protein 1-Phosphoglycerate mutase 5-Apoptosis induci
Externí odkaz:
https://doaj.org/article/317a6d1b31824467ba8780f2a56336e9
Akademický článek
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Autor:
Anees Rahman Cheratta, Faisal Thayyullathil, Simon A. Hawley, Fiona A. Ross, Abdelmajdid Atrih, Douglas J. Lamont, Siraj Pallichankandy, Karthikeyan Subburayan, Ameer Alakkal, Rachid Rezgui, Alex Gray, D. Grahame Hardie, Sehamuddin Galadari
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110761- (2022)
Summary: AMP-activated protein kinase (AMPK) coordinates energy homeostasis during metabolic and energy stress. We report that the catalytic subunit isoform AMPK-α1 (but not α2) is cleaved by caspase-3 at an early stage during induction of apoptosi
Externí odkaz:
https://doaj.org/article/dc89a458593d474787f73e8f3cb61c58
Autor:
Subburayan, Karthikeyan, Thayyullathil, Faisal, Pallichankandy, Siraj, Cheratta, Anees Rahman, Galadari, Sehamuddin ⁎
Publikováno v:
In Translational Oncology November 2020 13(11)
Autor:
Thayyullathil, Faisal a, Cheratta, Anees Rahman a, Pallichankandy, Siraj a, Subburayan, Karthikeyan a, Tariq, Saeed b, Rangnekar, Vivek M. c, Galadari, Sehamuddin a, ⁎
Publikováno v:
In BBA - Molecular Cell Research July 2020 1867(7)
Autor:
Faisal Thayyullathil, Anees Rahman Cheratta, Ameer Alakkal, Karthikeyan Subburayan, Siraj Pallichankandy, Yusuf A. Hannun, Sehamuddin Galadari
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Ferroptosis is a type of regulated cell death characterized by ROS accumulation and devastating lipid peroxidation (LPO). The role of acid sphingomyelinase (ASM), a key enzyme in sphingolipid metabolism, in the induction of apoptosis has bee
Externí odkaz:
https://doaj.org/article/c8750316cd794e7c925cca1370c4c6ba
Autor:
Anees Rahman Cheratta, Faisal Thayyullathil, Siraj Pallichankandy, Karthikeyan Subburayan, Ameer Alakkal, Sehamuddin Galadari
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract The tumor suppressor prostate apoptosis response-4 (Par-4) has recently turned ‘twenty-five’. Beyond its indisputable role as an apoptosis inducer, an increasing and sometimes bewildering, new roles for Par-4 are being reported. These ro
Externí odkaz:
https://doaj.org/article/6d08d6763e0c4245b7bf91ccef5023d8
Autor:
Ameer Alakkal, Faisal Thayyullathil, Siraj Pallichankandy, Karthikeyan Subburayan, Anees Rahman Cheratta, Sehamuddin Galadari
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1795 (2022)
Sanguinarine (SNG) is a benzophenanthridine alkaloid isolated mainly from Sanguinaria canadensis, Chelidonium majus, and Macleaya cordata. SNG is considered an antineoplastic agent based on its cytotoxic activity against various tumors. However, the
Externí odkaz:
https://doaj.org/article/1ee47b4a477e4f4a9ad27dc0e2a2d018
Autor:
Karthikeyan Subburayan, Faisal Thayyullathil, Siraj Pallichankandy, Anees Rahman Cheratta, Sehamuddin Galadari
Publikováno v:
Translational Oncology, Vol 13, Iss 11, Pp 100843- (2020)
Ferroptosis is a novel form of programmed cell death characterized by an iron-dependent increase in reactive oxygen species (ROS). However, the role of ROS in the regulation of ferroptosis remains elusive. In this study, for the first time, we demons
Externí odkaz:
https://doaj.org/article/61c14c00441e4dfcaafc84514cd89363