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Autor:
Ane Duarte, Géraldine H Petit, Maria Björkqvist, Patrik Brundin, Srikanth Ranganathan, Catarina R. Oliveira, Ana Cristina Rego, Jia-Yi Li
Publikováno v:
Experimental Neurology. 231:314-319
Huntington's disease (HD) is the most prevalent polyglutamine expansion disorder. HD is caused by an expansion of CAG triplet in the huntingtin (HTT) gene, associated with striatal and cortical neuronal loss. Central and peripheral metabolic abnormal