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Autor:
Oliver C. Steinbach, Andy van Driel, Maria L. H. Vlaming, Jeroen DeGroot, Harm T. Jansen, Charles Frederik Sio, Tilman Läppchen, José W.A. van der Hoorn, Evita van de Steeg, Suzanne Kivits
Publikováno v:
Nuclear medicine and biology. 42(11)
Introduction: The efflux transporters P-glycoprotein (P-gp, ABCB1) and breast cancer resistance protein (BCRP, ABCG2) are expressed at the blood-brain barrier (BBB), and can limit the access of a wide range of drugs to the brain. In this study we dev