Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Andy T. Y. Lau"'
Autor:
Dan-Dan Wu, Andy T. Y. Lau, Yan-Ming Xu, Marjan Reinders-Luinge, Mihaly Koncz, Antal Kiss, Wim Timens, Marianne G. Rots, Machteld N. Hylkema
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is highly expressed in smokers, but little is known about the molecular mechanism of UCHL1 in airway epithelium and its possible role in affecting extracellular matrix (ECM) remodelling in the underlyi
Externí odkaz:
https://doaj.org/article/2a12fdb3945348458e0b03b9495d19c6
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Epigenetic memory is essential for life that governs the predefined functional features of cells. Recent evidence has indicated that the epigenetic modification provides a potential link to gene expression changes that may be involved in the
Externí odkaz:
https://doaj.org/article/7adfce7160264ba4b3a6abe1c17872ca
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Epithelial cells can trans-differentiate into motile mesenchymal cells through a dynamic process known as epithelial–mesenchymal transition (EMT). EMT is crucial in embryonic development and wound healing but also contributes to human dise
Externí odkaz:
https://doaj.org/article/485086c708f445208c84619b8ed464a0
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Nuclear factor of activated T-cells, cytoplasmic 4 (NFATc4), a transcription factor of NFAT family, which is activated by Ca2+/calcineurin signaling. Recently, it is reported that aberrantly activated NFATc4 participated and modulated in the
Externí odkaz:
https://doaj.org/article/8eff80362efb4e70912020a86c85593b
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/6e20d684cd614d0d8e7400818af20f1f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Human transmembrane protein metal cation symporter ZIP8 (SLC39A8) is a member of the solute carrier gene family responsible for intracellular transportation of essential micronutrients, including manganese, selenium, and zinc. Previously, we establis
Externí odkaz:
https://doaj.org/article/b6fd964fcbde44f4b57a2529ad95da3c
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract The eukaryotic translation initiation factor 5A1 (eIF5A1) and its homolog eIF5A2 are the only two human proteins containing the unique post-translational modification–hypusination, which is essential for the function of these two proteins.
Externí odkaz:
https://doaj.org/article/b06bc51e0f3f483c8ea2010fead8cd3d
Publikováno v:
Molecules, Vol 28, Iss 4, p 1770 (2023)
In this review, we discuss the recent knowledge regarding the epigenetic effects of coffee extract and the three essential active ingredients in coffee (caffeine, chlorogenic acid, and caffeic acid). As a popular beverage, coffee has many active ingr
Externí odkaz:
https://doaj.org/article/3370d8b2d63f4e6684dca412944f403f
Publikováno v:
Toxics, Vol 10, Iss 7, p 363 (2022)
Smoking has been recognized by the World Health Organization (WHO) as the fifth highest threat to humanity. Smoking, a leading disease promoter, is a major risk factor for non-communicable diseases (NCDs) such as cancer, cardiovascular disease, diabe
Externí odkaz:
https://doaj.org/article/f18f8c75e6a945c596b468848f59966c
Publikováno v:
Toxics, Vol 10, Iss 2, p 50 (2022)
Since the rise and rapid development of nanoscale science and technology in the late 1980s, nanomaterials have been widely used in many areas including medicine, electronic products, crafts, textiles, and cosmetics, which have provided a lot of conve
Externí odkaz:
https://doaj.org/article/12bdb99807a8491fb4743fcb92fff933