Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Andy T Merritt"'
Autor:
David A. Baker, Lindsay B. Stewart, Jonathan M. Large, Paul W. Bowyer, Keith H. Ansell, María B. Jiménez-Díaz, Majida El Bakkouri, Kristian Birchall, Koen J. Dechering, Nathalie S. Bouloc, Peter J. Coombs, David Whalley, Denise J. Harding, Ela Smiljanic-Hurley, Mary C. Wheldon, Eloise M. Walker, Johannes T. Dessens, María José Lafuente, Laura M. Sanz, Francisco-Javier Gamo, Santiago B. Ferrer, Raymond Hui, Teun Bousema, Iñigo Angulo-Barturén, Andy T. Merritt, Simon L. Croft, Winston E. Gutteridge, Catherine A. Kettleborough, Simon A. Osborne
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Protein kinases are promising drug targets for treatment of malaria. Here, starting with a medicinal chemistry approach, Baker et al. generate an imidazopyridine that selectively targets Plasmodium falciparum PKG, inhibits blood stage parasite growth
Externí odkaz:
https://doaj.org/article/0c48607312374096801bf91f077ff9c0
Publikováno v:
The Journal of Organic Chemistry. 66:3284-3290
The palladium-catalyzed reaction of pinacolone with tert-butyldimethyl(3-(2-bromophenyl)allyloxy)silane results in direct formation of 1-vinyl-3-tert-butyl-1H-isochromene. This is the result of a ketone arylation followed by an intramolecular cycliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c672859b1d2f218dc39c75249b5f2ce
https://doi.org/10.1021/jo0011991
https://doi.org/10.1021/jo0011991
ChemInform Abstract: Palladium-Catalyzed Tandem Reactions to Form 1-Vinyl-1H-isochromene Derivatives
Publikováno v:
ChemInform. 32
The palladium-catalyzed reaction of pinacolone with tert-butyldimethyl(3-(2-bromophenyl)allyloxy)silane results in direct formation of 1-vinyl-3-tert-butyl-1H-isochromene. This is the result of a ketone arylation followed by an intramolecular cycliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0c94ff9fc963c502aea143293c4dc7
https://doi.org/10.1002/chin.200138133
https://doi.org/10.1002/chin.200138133
Autor:
Andy T. Merritt, Peter N. Lowe, Andrew Lockhart, Guizhu Hong, Liang Ye, Jennifer L. Morgenstern, Antony D. Gee, John Brown, Duncan B. Judd
Publikováno v:
The Journal of biological chemistry. 280(9)
Imaging the progression of Alzheimer's disease would greatly facilitate the discovery of therapeutics, and a wide range of ligands are currently under development for the detection of beta-amyloid peptide (Abeta)-containing plaques by using positron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe6a8fc2696367901ead37463ed111d
https://pubmed.ncbi.nlm.nih.gov/15615711
https://pubmed.ncbi.nlm.nih.gov/15615711
Autor:
Alastair Binnie, Stephen P Watson, Andy T Merritt, Tom H Mander, Martin J. Valler, Jane C Denyer, Darren V. S. Green, Jane A Lewis, Brian Evans, Mary C Donnelly, Brian Cox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::337f3a83b8c17bd0bc2c77eab7b7613c
https://doi.org/10.1016/s0079-6468(08)70058-4
https://doi.org/10.1016/s0079-6468(08)70058-4
