Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andy Stocker"'
Autor:
Paul Robert Owen Whittamore, Nidhal Selmi, Andy Stocker, Peter W. Kenny, Stuart Norman Lile Bennett, Adrian Pickup, Andrew D. Campbell, Alleyn T. Plowright, Craig Johnstone, David Whalley, Iain Simpson, Andrew Hancock
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3511-3514
A series of carboxylic acid glycogen phosphorylase inhibitors, which have potential as oral antidiabetic agents, is described. Defining and applying simple physicochemical design criteria was used to assess the opportunity and to focus synthetic effo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f5c3c4f7593eea071ca91aef6a97e5
https://doi.org/10.1016/j.bmcl.2010.04.147
https://doi.org/10.1016/j.bmcl.2010.04.147
Autor:
Michael Butters, Alan Martin Birch, Peter W. Kenny, Pawel Siedlecki, Paul Robert Owen Whittamore, Jennifer Whitehouse, Ludovic Otterbein, Matthew S. Addie, Andrew Pannifer, Melvyn J. Taylor, Paul M. Murray, Linda Godfrey, David Whalley, Andy Stocker, Jeremy S. Parker, Andrew David Morley, Nikos G. Oikonomakos, Kristy Readman, Linda A. Townsend, Stuart Norman Lile Bennett, Paul Schofield
Publikováno v:
Bioorganic & Medicinal Chemistry Letters 16:21(Nov2006):5567-5571
Two series of novel thienopyrrole inhibitors of recombinant human liver glycogen phosphorylase a (GPa) which are effective in reducing glucose output from rat hepatocytes are described. Representative compounds have been shown to bind at the dimer in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a027fdd96a6fc9f365265c8ad7e44fb1
https://pubmed.ncbi.nlm.nih.gov/16945526
https://pubmed.ncbi.nlm.nih.gov/16945526