Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andy Shao"'
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 94-94 (2024)
OBJECTIVES/GOALS: The goal of this study is to reveal strong candidate genes for inherited retinal diseases (IRDs) in humans to better understand the mechanisms behind IRD development and reveal potential therapeutic targets. We hope these findings w
Externí odkaz:
https://doaj.org/article/daede4a950be406e9265850a83bd1d82
Autor:
Kendall Higgins, Bret A. Moore, Zorana Berberovic, Hibret A. Adissu, Mohammad Eskandarian, Ann M. Flenniken, Andy Shao, Denise M. Imai, Dave Clary, Louise Lanoue, Susan Newbigging, Lauryl M. J. Nutter, David J. Adams, Fatima Bosch, Robert E. Braun, Steve D. M. Brown, Mary E. Dickinson, Michael Dobbie, Paul Flicek, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D. Heaney, Yann Herault, Martin Hrabe de Angelis, Hsian-Jean Genie Chin, Fabio Mammano, Chuan Qin, Toshihiko Shiroishi, Radislav Sedlacek, J.-K. Seong, Ying Xu, The IMPC Consortium, K. C. Kent Lloyd, Colin McKerlie, Ala Moshiri
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract We searched a database of single-gene knockout (KO) mice produced by the International Mouse Phenotyping Consortium (IMPC) to identify candidate ciliopathy genes. We first screened for phenotypes in mouse lines with both ocular and renal or
Externí odkaz:
https://doaj.org/article/c0d5d5cc412449dba2430740f3a4e375
Autor:
Andy Shao, Antonio Jacobo Lopez, JiaJia Chen, Addy Tham, Seanne Javier, Alejandra Quiroz, Sonia Frick, Edward M. Levine, K. C. Kent Lloyd, Brian C. Leonard, Christopher J. Murphy, Thomas M. Glaser, Ala Moshiri
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 7 (2022)
Retinitis pigmentosa (RP), a retinal degenerative disease, is the leading cause of heritable blindness. Previously, we described that Arap1−/− mice develop a similar pattern of photoreceptor degeneration. Arap1 is an Arf-directed GTPase-activatin
Externí odkaz:
https://doaj.org/article/1e0ef4641f5c422b9cd28293ca0d8764
Autor:
Andy Shao, Antonio Jacobo Lopez, JiaJia Chen, Addy Tham, Seanne Javier, Alejandra Quiroz, Sonia Frick, Edward M. Levine, K. C. Kent Lloyd, Brian C. Leonard, Christopher J. Murphy, Thomas M. Glaser, Ala Moshiri
Publikováno v:
Disease modelsmechanisms. 15(7)
Retinitis pigmentosa (RP), a retinal degenerative disease, is the leading cause of heritable blindness. Previously, we described that Arap1−/− mice develop a similar pattern of photoreceptor degeneration. Arap1 is an Arf-directed GTPase-activatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c586f12628f1254acff9de635519878d
https://pubmed.ncbi.nlm.nih.gov/35758026
https://pubmed.ncbi.nlm.nih.gov/35758026
Autor:
Brian C. Leonard, Seanne Javier, Thomas M Glaser, Addy Tham, Andy Shao, Ala Moshiri, Sonia L. Frick, Alejandra Quiroz, Antonio Jacobo Lopez, Jiajia Chen, Edward M. Levine, Christopher J. Murphy, Kevin C K Lloyd
PurposeArap1 is an Arf-directed GTPase-activating protein (GAP) shown to modulate actin cytoskeletal dynamics by regulating Arf and Rho family members. We have previously shown that Arap1-/- mice develop photoreceptor degeneration similar to the huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f55ed14e2fd2a2cf5eb8b4d8f2e7f88a
https://doi.org/10.1101/2021.08.09.455745
https://doi.org/10.1101/2021.08.09.455745
Publikováno v:
Cancer Research. 79:1612-1612
Standard treatments for prostate cancer typically involve androgen deprivation therapy (ADT). In later stages of prostate cancer, the tumor typically evolves to become insensitive to ADT, otherwise known as castration-resistant prostate cancer (CRPC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89acdf06d3a34f076f0f8e92d8328380
https://doi.org/10.1158/1538-7445.am2019-1612
https://doi.org/10.1158/1538-7445.am2019-1612