Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Andy Rampersaud"'
Publikováno v:
eLife, Vol 12 (2023)
Sex differences in plasma growth hormone (GH) profiles, pulsatile in males and persistent in females, regulate sex differences in hepatic STAT5 activation linked to sex differences in gene expression and liver disease susceptibility, but little is un
Externí odkaz:
https://doaj.org/article/685a18209ee34a928afdad8a23570443
Publikováno v:
Toxicol Sci
Constitutive androstane receptor (CAR) (Nr1i3), a liver nuclear receptor and xenobiotic sensor, induces drug, steroid, and lipid metabolism and dysregulates genes linked to hepatocellular carcinogenesis, but its impact on the liver epigenome is poorl
Publikováno v:
Toxicological Sciences. 164:115-128
Activation of the nuclear receptor and transcription factor CAR (Nr1i3) by its specific agonist ligand TCPOBOP (1, 4-bis[2-(3, 5-dichloropyridyloxy)]benzene) dysregulates hundreds of genes in mouse liver and is linked to male-biased hepatocarcinogene
Publikováno v:
Toxicological Sciences. 159:25-41
Xenobiotic agonists of constitutive androstane receptor (CAR) induce many hepatic drug metabolizing enzymes, but following prolonged exposure, promote hepatocellular carcinoma, most notably in male mouse liver. Here, we used nuclear RNA-seq to charac
Publikováno v:
Endocrinology. 158:1386-1405
Sex differences in pituitary growth hormone (GH) secretion (pulsatile in males vs near continuous/persistent in females) impart sex-dependent expression to hundreds of genes in adult mouse liver. Signal transducer and activator of transcription (STAT
Publikováno v:
The FASEB Journal. 29
Publikováno v:
The FASEB Journal. 27
Autor:
Eriko Yamada, Geraldine M. O’Connor, Rasmi Thomas, Andy Rampersaud, Mary Carrington, Daniel W. McVicar
NK cell activity is regulated by the integration of positive and negative signals. One important source of these signals for human NK cells is the killer Ig-like receptor (KIR) family, which includes both members that transduce positive and those tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26500b6134d556458eb4e4ea88420e30
https://europepmc.org/articles/PMC3159812/
https://europepmc.org/articles/PMC3159812/
Publikováno v:
The Journal of Immunology. 184:89.55-89.55
The Killer cell Immunoglobulin-like Receptor (KIR) family of NK receptors contains both activating (e.g. 3DS1) and inhibitory (e.g. 3DL1) members. Unlike 3DL1, for which binding to HLA-Bw4 has been characterized, direct binding of HLA to 3DS1 has not