Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Andy Nam"'
Autor:
Chin Wee Tan, Jinjin Chen, Ning Liu, Dharmesh D. Bhuva, Tony Blick, James Monkman, Caroline Cooper, Malvika Kharbanda, Kristen Feher, Belinda Phipson, Emily E. Killingbeck, Liuliu Pan, Youngmi Kim, Yan Liang, Andy Nam, Michael Leon, Paulo Souza-Fonseca-Guimaraes, Seigo Nagashima, Ana Paula Camargo Martins, Cleber Machado-Souza, Lucia de Noronha, Benjamin Tang, Kirsty Short, John Fraser, Gabrielle T. Belz, Fernando Souza-Fonseca-Guimaraes, Arutha Kulasinghe, Melissa J. Davis
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105016- (2024)
Summary: The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages to have elevated expression of IFI27 in areas of infection.
Externí odkaz:
https://doaj.org/article/4f2fdb2f06f84144987d21c5de056820
Autor:
Wen Juan Tu, Michelle Melino, Jenny Dunn, Robert D. McCuaig, Helle Bielefeldt-Ohmann, Sofiya Tsimbalyuk, Jade K. Forwood, Taniya Ahuja, John Vandermeide, Xiao Tan, Minh Tran, Quan Nguyen, Liang Zhang, Andy Nam, Liuliu Pan, Yan Liang, Corey Smith, Katie Lineburg, Tam H. Nguyen, Julian D. J. Sng, Zhen Wei Marcus Tong, Keng Yih Chew, Kirsty R. Short, Roger Le Grand, Nabila Seddiki, Sudha Rao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract In vitro, ACE2 translocates to the nucleus to induce SARS-CoV-2 replication. Here, using digital spatial profiling of lung tissues from SARS-CoV-2-infected golden Syrian hamsters, we show that a specific and selective peptide inhibitor of nu
Externí odkaz:
https://doaj.org/article/c807331d48fd44e7b2a60c1357a9b798
Autor:
Deniz Bakkalci, Georgina Al-Badri, Wei Yang, Andy Nam, Yan Liang, Syed Ali Khurram, Susan Heavey, Stefano Fedele, Umber Cheema
Publikováno v:
Materials Today Bio, Vol 24, Iss , Pp 100923- (2024)
Stromal cells are key components of the tumour microenvironment (TME) and their incorporation into 3D engineered tumour-stroma models is essential for tumour mimicry. By engineering tumouroids with distinct tumour and stromal compartments, it has bee
Externí odkaz:
https://doaj.org/article/977c36513ebd473c84c94da9666fe446
Autor:
Nataly Stylianou, Ismail Sebina, Nicholas Matigian, James Monkman, Hadeel Doehler, Joan Röhl, Mark Allenby, Andy Nam, Liuliu Pan, Anja Rockstroh, Habib Sadeghirad, Kimberly Chung, Thais Sobanski, Ken O'Byrne, Ana Clara Simoes Florido Almeida, Patricia Zadorosnei Rebutini, Cleber Machado‐Souza, Emanuele Therezinha Schueda Stonoga, Majid E Warkiani, Carlos Salomon, Kirsty Short, Lana McClements, Lucia deNoronha, Ruby Huang, Gabrielle T Belz, Fernando Souza‐Fonseca‐Guimaraes, Vicki Clifton, Arutha Kulasinghe
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 2, Pp n/a-n/a (2024)
Abstract Objectives Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus infection in pregnancy is associated with higher incidence of placental dysfunction, referred to by a few studies as a ‘preeclampsia‐like syndrome’. Howe
Externí odkaz:
https://doaj.org/article/c26444dbfdab4c58aeeef3df629fe26a
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Maize shoot development progresses from non-pigmented meristematic cells at the base of the leaf to expanded and non-dividing green cells of the leaf blade. This transition is accompanied by the conversion of promitochondria and proplastids to their
Externí odkaz:
https://doaj.org/article/572aae4f909649d281185ff20a0cf2f6
Autor:
Arutha Kulasinghe, Ning Liu, Chin Wee Tan, James Monkman, Jane E Sinclair, Dharmesh D Bhuva, David Godbolt, Liuliu Pan, Andy Nam, Habib Sadeghirad, Kei Sato, Gianluigi Li Bassi, Ken O’Byrne, Camila Hartmann, Anna Flavia Ribeiro dos Santo Miggiolaro, Gustavo Lenci Marques, Lidia Zytynski Moura, Derek Richard, Mark Adams, Lucia de Noronha, Cristina Pellegrino Baena, Jacky Y Suen, Rakesh Arora, Gabrielle T. Belz, Kirsty R Short, Melissa J Davis, Fernando Souza-FonsecaGuimaraes, John F Fraser
Publikováno v:
Immunology. 168:403-419
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to present with pulmonary and extra-pulmonary organ complications. In comparison with the 2009 pandemic (pH1N1), SARS-CoV-2 infection is likely to lead to more severe disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8982c7d44ce79d34ae0e26f17b0318
https://doi.org/10.1111/imm.13577
https://doi.org/10.1111/imm.13577
Autor:
Nataly Stylianou, Ismail Sebina, Nicholas Matigian, James Monkman, Hadeel Doehler, Joan Röhl, Mark Allenby, Andy Nam, Liuliu Pan, Anja Rockstroh, Habib Sadeghirad, Kimberly Chung, Thais Sobanski, Ken O’Byrne, Patricia Zadorosnei Rebutini, Cleber Machado-Souza, Emanuele Therezinha Schueda Stonoga, Majid E Warkiani, Carlos Salomon, Kirsty Short, Lana McClements, Lucia de Noronha, Ruby Huang, Gabrielle T. Belz, Fernando Souza-Fonseca-Guimaraes, Vicki Clifton, Arutha Kulasinghe
In recent years, pregnant people infected with the SARS-CoV-2 virus have shown a higher incidence of “preeclampsia-like syndrome”. Preeclampsia is a systematic syndrome that affects 5-8 % of pregnant people worldwide and is the leading cause of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9b636d00468dd3f0a67ccf847e74772
https://doi.org/10.1101/2023.01.20.524893
https://doi.org/10.1101/2023.01.20.524893
Autor:
Deniz Bakkalci, Georgina Al-Badri, Wei Yang, Andy Nam, Yan Liang, Syed Ali Khurram, Susan Heavey, Stefano Fedele, Umber Cheema
Bioengineering facets of the tumour microenvironment (TME) are essential in 3D tissue models to accurately recapitulate tumour progression. Stromal cells are key components of the TME and their incorporation into 3D biomimetic bioengineered tumour-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::383ae06d35d0493f194b4b85913d9c5c
https://doi.org/10.1101/2022.12.13.520130
https://doi.org/10.1101/2022.12.13.520130
Neuregulin-1 (NRG-1) has been shown to be neuroprotective and anti-inflammatory in rodent models following focal brain ischemia. However, the spatial transcriptional mechanisms involved in the effects of NRG-1 have not been investigated. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4787678ffa82232030ca229702fb3ecf
https://doi.org/10.21203/rs.3.rs-2256390/v1
https://doi.org/10.21203/rs.3.rs-2256390/v1
Autor:
Yered Pita-Juarez, Dimitra Karagkouni, Nikolaos Kalavros, Johannes C. Melms, Sebastian Niezen, Toni M. Delorey, Adam L Essene, Olga R. Brook, Deepti Pant, Disha Skelton-Badlani, Pourya Naderi, Pinzhu Huang, Liuliu Pan, Tyler Hether, Tallulah S. Andrews, Carly G.K. Ziegler, Jason Reeves, Andriy Myloserdnyy, Rachel Chen, Andy Nam, Stefan Phelan, Yan Liang, Amit Dipak Amin, Jana Biermann, Hanina Hibshoosh, Molly Veregge, Zachary Kramer, Christopher Jacobs, Yusuf Yalcin, Devan Phillips, Michal Slyper, Ayshwarya Subramanian, Orr Ashenberg, Zohar Bloom-Ackermann, Victoria M. Tran, James Gomez, Alexander Sturm, Shuting Zhang, Stephen J. Fleming, Sarah Warren, Joseph Beechem, Deborah Hung, Mehrtash Babadi, Robert F. Padera, Sonya A. MacParland, Gary D. Bader, Nasser Imad, Isaac H. Solomon, Eric Miller, Stefan Riedel, Caroline B.M. Porter, Alexandra-Chloé Villani, Linus T.-Y. Tsai, Winston Hide, Gyongyi Szabo, Jonathan Hecht, Orit Rozenblatt-Rosen, Alex K. Shalek, Benjamin Izar, Aviv Regev, Yury Popov, Z. Gordon Jiang, Ioannis S. Vlachos
Publikováno v:
bioRxiv : the preprint server for biology.
The molecular underpinnings of organ dysfunction in acute COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we performed single-nucleus RNA-seq and spatial transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd10833ef100648eb315ed90fe2285a
https://pubmed.ncbi.nlm.nih.gov/36324805
https://pubmed.ncbi.nlm.nih.gov/36324805