Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andy M. Zuniga"'
Autor:
Philip Jones, Nancy E. Kohl, Timothy P. Heffernan, Joseph R. Marszalek, Giulio F. Draetta, Andy M. Zuniga, Simon S. Yu, Christopher C. Williams, Erika Suzuki, Nakia D. Spencer, Sahil Seth, Vandhana Ramamoorthy, Michael Peoples, Robert A. Mullinax, Meredith A. Miller, Timothy McAfoos, Pijus K. Mandal, Xiaoyan Ma, Anastasia M. Lopez, Chiu-Yi Liu, Jeffrey J. Kovacs, Zhijun Kang, Yongying Jiang, Justin K. Huang, Virginia Giuliani, Sonal Gera, Guang Gao, Ningping Feng, Qing Chang, Christopher L. Carroll, Caroline C. Carrillo, Jason P. Burke, Christopher A. Bristow, Benjamin J. Bivona, Maria Emilia Di Francesco, Jason B. Cross, Connor A. Parker, Sarah Johnson, Qi Wu, Angela L. Harris, Faika Mseeh, Paul Leonard, Barbara Czako, Brooke A. Meyers, Yuting Sun
Src homology 2 domain-containing phosphatase (SHP2) is a phosphatase that mediates signaling downstream of multiple receptor tyrosine kinases (RTK) and is required for full activation of the MAPK pathway. SHP2 inhibition has demonstrated tumor growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679aa5c2787960118aa25b0d20d0a771
https://doi.org/10.1158/0008-5472.c.6512119.v1
https://doi.org/10.1158/0008-5472.c.6512119.v1
Autor:
Philip Jones, Nancy E. Kohl, Timothy P. Heffernan, Joseph R. Marszalek, Giulio F. Draetta, Andy M. Zuniga, Simon S. Yu, Christopher C. Williams, Erika Suzuki, Nakia D. Spencer, Sahil Seth, Vandhana Ramamoorthy, Michael Peoples, Robert A. Mullinax, Meredith A. Miller, Timothy McAfoos, Pijus K. Mandal, Xiaoyan Ma, Anastasia M. Lopez, Chiu-Yi Liu, Jeffrey J. Kovacs, Zhijun Kang, Yongying Jiang, Justin K. Huang, Virginia Giuliani, Sonal Gera, Guang Gao, Ningping Feng, Qing Chang, Christopher L. Carroll, Caroline C. Carrillo, Jason P. Burke, Christopher A. Bristow, Benjamin J. Bivona, Maria Emilia Di Francesco, Jason B. Cross, Connor A. Parker, Sarah Johnson, Qi Wu, Angela L. Harris, Faika Mseeh, Paul Leonard, Barbara Czako, Brooke A. Meyers, Yuting Sun
Supplementary Materials and Methods Supplementary References Tables S1 to S3 and legends Figures S1 to S4 and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb5082d82bd02f09e6060ee7ba89279
https://doi.org/10.1158/0008-5472.22425706.v1
https://doi.org/10.1158/0008-5472.22425706.v1
Autor:
Akira Inoue, Takashi Shingu, Johnathon L. Rose, Xiaoyan Ma, Christopher A. Bristow, Takahiro Kodama, Alessandro Carugo, Andy M. Zuniga, Angela K. Deem, Giannicola Genovese, Timothy P. Heffernan, Bahar Salimian Rizi, Frederick S. Robinson, Joseph R. Daniele, Ningping Feng, Scott Kopetz, Rosalba Minelli, Mary Sobieski, Kadir C. Akdemir, Jason Roszik, Robert A. Mullinax, Sahil Seth, Michael Peoples, Hideo Tomihara, David G. Menter, Clifford Stephan, Sanjana Srinivasan, Giulio Draetta, Sara Loponte, Yonathan Lissanu Deribe, David Brunell, Virginia Giuliani, Tin Oo Khor, Angela L. Harris, Andrea Viale
Publikováno v:
Gastroenterology. 161(1)
Background & Aims Understanding the mechanisms by which tumors adapt to therapy is critical for developing effective combination therapeutic approaches to improve clinical outcomes for patients with cancer. Methods To identify promising and clinicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f698b264050723f59e7b5f4cf101237
https://pubmed.ncbi.nlm.nih.gov/33798528
https://pubmed.ncbi.nlm.nih.gov/33798528
Autor:
Qing Chang, Simon S. Yu, Christopher A. Bristow, Meredith A. Miller, Pijus K. Mandal, Yongying Jiang, Maria Emilia Di Francesco, Angela L. Harris, Christopher Carroll, Jason P Burke, Brooke A. Meyers, Zhijun Kang, Erika Suzuki, Cross Jason, Qi Wu, Connor A. Parker, Timothy McAfoos, Guang Gao, Sarah B. Johnson, Nancy E. Kohl, Ningping Feng, Yuting Sun, Chiu Yi Liu, Caroline C. Carrillo, Andy M. Zuniga, Paul G. Leonard, Sahil Seth, Virginia Giuliani, Faika Mseeh, Timothy P. Heffernan, Jeffrey J. Kovacs, Joseph R. Marszalek, Barbara Czako, Justin K. Huang, Giulio Draetta, Christopher C. Williams, Xiaoyan Ma, Anastasia M. Lopez, Nakia D. Spencer, Robert A. Mullinax, Vandhana Ramamoorthy, Philip Jones, Sonal Gera, Benjamin J. Bivona, Michael Peoples
Publikováno v:
Cancer research. 80(21)
Src homology 2 domain-containing phosphatase (SHP2) is a phosphatase that mediates signaling downstream of multiple receptor tyrosine kinases (RTK) and is required for full activation of the MAPK pathway. SHP2 inhibition has demonstrated tumor growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614d2e4bc8f9b4ddee8a36ce57a0dcd4
https://pubmed.ncbi.nlm.nih.gov/32928921
https://pubmed.ncbi.nlm.nih.gov/32928921
Autor:
Barbara Czako, Angela L. Harris, Sonal Sonal, Sarah B. Johnson, Mikhila Mahendra, Faika Mseeh, Erika Suzuki, Nakia D. Spencer, Ningping Feng, Andy M. Zuniga, Jason P Burke, Martin Tremblay, Zhen Liu, Tin Oo Khor, Joseph R. Marszalek, Jeffrey J. Kovacs, Timothy P. Heffernan, Robert A. Mullinax, Philip Jones, Keith Mikule
Publikováno v:
Cancer Research. 78:LB-124
Tumor-associated macrophages (TAMs) are critical drivers of tumor progression and immunosuppression within the tumor microenvironment. The dominant TAM phenotype is broadly characterized as harboring M2-like macrophage properties, which are anti-infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c359b7fff872a86a15857010577854
https://doi.org/10.1158/1538-7445.am2018-lb-124
https://doi.org/10.1158/1538-7445.am2018-lb-124
Autor:
Alessia Petrocchi, Naphtali J. Reyna, Faika Mseeh, Connor A. Parker, Simon Yu, Quanyun Xu, Ningping Feng, Paul Leonard, Norma Rogers, Jason B. Cross, Angela L. Harris, Yongying Jiang, Tin Oo Khor, Mikhila G. Mahendra, Jihai Pang, Qi Wu, Andy M. Zuniga, Timothy McAfoos, Matthew M. Hamilton, Joe R. Marszalek, Keith Mikule, Paul Vancutsem, Keith Wilcoxen, Martin Tremblay, Philip Jones, Richard T. Lewis
Publikováno v:
Cancer Research. 78:LB-071
Indoleamine 2,3-dioxygenase (IDO1 and IDO2) and tryptophan dioxygenase (TDO) are heme-containing enzymes that mediate the rate limiting step in the oxidative degradation of L-tryptophan (L-TRP) to kynurenine (KYN) metabolites. Tryptophan catabolism t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0efdf3558a82bc49107b3bec62cbd8
https://doi.org/10.1158/1538-7445.am2018-lb-071
https://doi.org/10.1158/1538-7445.am2018-lb-071