Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Andy Kuo"'
Publikováno v:
F1000Research, Vol 9 (2020)
Strong opioid analgesics are the mainstay of therapy for the relief of moderate to severe acute nociceptive pain that may occur post-operatively or following major trauma, as well as for the management of chronic cancer-related pain. Opioid-related a
Externí odkaz:
https://doaj.org/article/86ec94bc838042ecb383667d04156457
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 940 (2021)
Cisplatin, which is a chemotherapy drug listed on the World Health Organisation’s List of Essential Medicines, commonly induces dose-limiting side effects including chemotherapy-induced peripheral neuropathy (CIPN) that has a major negative impact
Externí odkaz:
https://doaj.org/article/ca7592ca24da4ac08200bdf88de3be31
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss , Pp - (2019)
Chronic low back pain (LBP) ranks among the most common reasons for patient visits to healthcare providers. Drug treatments often provide only partial pain relief and are associated with considerable side-effects. J-2156 [(1’S,2S)-4amino-N-(1’-ca
Externí odkaz:
https://doaj.org/article/63cac63af2264a3bab7a199ebf6643f0
Autor:
Priyank A. Shenoy, Andy Kuo, Nemat Khan, Louise Gorham, Janet R. Nicholson, Laura Corradini, Irina Vetter, Maree T. Smith
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
In the majority of patients with breast cancer in the advanced stages, skeletal metastases are common, which may cause excruciating pain. Currently available drug treatments for relief of breast cancer-induced bone pain (BCIBP) include non-steroidal
Externí odkaz:
https://doaj.org/article/eaa4d15ce2c74745bd145a32e74f7e41
Autor:
Arjun Muralidharan, Thomas S. W. Park, John T. Mackie, Luiz G. S. Gimenez, Andy Kuo, Janet R. Nicholson, Laura Corradini, Maree T. Smith
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Chronic low back pain (LBP), the leading cause of disability globally, is notoriously difficult to treat. Most rodent models of LBP mimic lumbar radicular pain rather than mechanical LBP. Here, we describe establishment of a new rat model of mechanic
Externí odkaz:
https://doaj.org/article/9e21855d3665473b9cd68516c18dcdf6
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
In the majority of patients with advanced breast cancer, there is metastatic spread to bones resulting in pain. Clinically available drug treatments for alleviation of breast cancer-induced bone pain (BCIBP) often produce inadequate pain relief due t
Externí odkaz:
https://doaj.org/article/ddd37afce3784044886d4ce78ce0f672
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
The majority of patients with terminal breast cancer show signs of bone metastasis, the most common cause of pain in cancer. Clinically available drug treatment options for the relief of cancer-associated bone pain are limited due to either inadequat
Externí odkaz:
https://doaj.org/article/26a5989ea92c464db7d2b332cbb52633
Publikováno v:
Journal of Medicinal Chemistry. 66:3746-3784
Autor:
Mohammad Zafar Imam, Andy Kuo, Sussan Ghassabian, Yunxin Cai, Yajuan Qin, Tingyou Li, Maree T. Smith
Publikováno v:
Pharmacological Reports. 75:634-646
Background Strong opioid analgesics such as morphine alleviate moderate to severe acute nociceptive pain (e.g. post-surgical or post-trauma pain) as well as chronic cancer pain. However, they evoke many adverse effects and so there is an unmet need f
Publikováno v:
Spinal Cord Series and Cases. 9