Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Andy Kokaji"'
Publikováno v:
The Journal of Immunology. 206:55.11-55.11
Macrophages are important and also have critical roles in the development and homeostasis of tissues and organs. Our understanding of macrophages is constantly evolving and expanding, as they are actively studied in many areas of research, including
Autor:
Yanet Valdez, Stephen K. Kyei, Grace F.T. Poon, Andy Kokaji, Steven M. Woodside, Allen C. Eaves, Terry E. Thomas
Publikováno v:
The Journal of Immunology. 200:51.13-51.13
Innate lymphoid cells (ILCs) are exceedingly rare but important regulators of homeostatic and disease-associated immune processes. The frequency of ILCs in peripheral blood of healthy humans is ~0.07% of CD45+ leukocytes. ILCs lack specific cell surf
Human regulatory T cell isolation in 55 minutes using EasySep™ Releasable RapidSpheres™ (TECH2P.912)
Autor:
Andy Kokaji, C. Sun, G. MacDonald, Samuel Clarke, Maureen Fairhurst, Allen Eaves, Terry Thomas
Publikováno v:
The Journal of Immunology. 194:206.22-206.22
The preferred marker for identifying regulatory T cells (Tregs) is FOXP3 but its intracellular localization currently precludes it from being used for isolating viable cells. Human FOXP3+ Tregs are characterized as CD4+ T cells expressing high levels
Autor:
Andy Kokaji, G. MacDonald, C. Sun, Drew Kellerman, Tim Le Fevre, Nathan Leung, Victoria Ng, Nooshin Tabatabaei-Zavareh, Karina McQueen, Maureen Fairhurst, Terry Thomas, Allen Eaves
Publikováno v:
The Journal of Immunology. 192:135.2-135.2
Human whole blood is made up of 93-96% red blood cells (RBCs), 4-7% platelets and 0.1-0.2% leukocytes consisting mainly of granulocytes, lymphocytes and monocytes. Due to the low frequency of lymphocyte subsets within whole blood, their isolation typ
Autor:
Nooshin Tabatabaei-Zavareh, Tim Le Fevre, Andy Kokaji, Karina McQueen, Maureen Fairhurst, Terry Thomas, Allen Eaves
Publikováno v:
The Journal of Immunology. 192:135.1-135.1
Neutrophils are the first line of defense against microbial infections. They sense pathogen-associated molecular patterns through a wide range of receptors including toll-like receptors. Once activated, neutrophils eliminate infection via the phagocy
Publikováno v:
The Journal of Immunology. 192:60.3-60.3
Regulatory T cells (Tregs), a subset of lymphocytes, play a key role in maintaining peripheral tolerance, preventing autoimmune diseases and limiting chronic inflammatory diseases. They can be broadly classified into natural or adaptive (induced) Tre
Autor:
Andy Kokaji, Vesna Posarac, Luciana Tonelli, Jeong Hun Sun, Armon Molavi, Maureen Fairhurst, Karina McQueen, Terry Thomas
Publikováno v:
The Journal of Immunology. 190:135.23-135.23
Effective cellular immunity requires naïve CD4+ and CD8+ T cells to undergo activation, proliferation and differentiation into various effector cell populations following antigen exposure. CD4+ and CD8+ T cell activation induces the production of c
Column-free isolation of untouched CD4+CD127lowCD49d- human regulatory T cells in 45 minutes (168.4)
Publikováno v:
The Journal of Immunology. 186:168.4-168.4
Regulatory T cells (Tregs) are a subset of lymphocytes that play a key role in maintaining immune homeostasis. The isolation of highly purified Tregs is essential for advancing this exciting field of research. FOXP3 remains the best marker for the id
Publikováno v:
The Journal of Immunology. 184:143.41-143.41
Regulatory T cells (Tregs) are a specialized subset of T cells that play a key role in immune regulation. Harnessing the suppressive function of Tregs is a major area of interest as they hold great potential for the treatment of autoimmune disorders.