Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Andy G X Zeng"'
Autor:
Andy G. X. Zeng, Suraj Bansal, Liqing Jin, Amanda Mitchell, Weihsu Claire Chen, Hussein A. Abbas, Michelle Chan-Seng-Yue, Veronique Voisin, Peter van Galen, Anne Tierens, Meyling Cheok, Claude Preudhomme, Hervé Dombret, Naval Daver, P. Andrew Futreal, Mark D. Minden, James A. Kennedy, Jean C. Y. Wang, John E. Dick
Publikováno v:
Nature Medicine. 28:1212-1223
The treatment landscape of acute myeloid leukemia (AML) is evolving, with promising therapies entering clinical translation, yet patient responses remain heterogeneous, and biomarkers for tailoring treatment are lacking. To understand how disease het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d9637cf0aa188862b6f4599d53fd65
https://doi.org/10.1038/s41591-022-01819-x
https://doi.org/10.1038/s41591-022-01819-x
Autor:
Liberalis Debraj Boila, Subhadeep Ghosh, Subham K. Bandyopadhyay, Liqing Jin, Alex Murison, Andy G. X. Zeng, Wasim Shaikh, Satyaki Bhowmik, Siva Sai Naga Anurag Muddineni, Mayukh Biswas, Sayantani Sinha, Shankha Subhra Chatterjee, Nathan Mbong, Olga I. Gan, Anwesha Bose, Sayan Chakraborty, Andrea Arruda, James A. Kennedy, Amanda Mitchell, Eric R. Lechman, Debasis Banerjee, Michael Milyavsky, Mark D. Minden, John E. Dick, Amitava Sengupta
Acute myeloid leukemia (AML) is a heterogeneous, aggressive malignancy with dismal prognosis and with limited availability of targeted therapies. Epigenetic deregulation contributes to AML pathogenesis. KDM6 proteins are histone-3-lysine-27-demethyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7be9e8d5a34e0c1351af4705016a39e
https://doi.org/10.21203/rs.3.rs-2064697/v1
https://doi.org/10.21203/rs.3.rs-2064697/v1
Autor:
James L C Che, Daniel Bode, Iwo Kucinski, Alyssa H Cull, Fiona Bain, Hans J Becker, Maria Jassinskaja, Melania Barile, Grace Boyd, Miriam Belmonte, Andy G X Zeng, Kyomi J Igarashi, Juan Rubio‐Lara, Mairi S Shepherd, Anna Clay, John E Dick, Adam C Wilkinson, Hiromitsu Nakauchi, Satoshi Yamazaki, Berthold Göttgens, David G Kent
Publikováno v:
EMBO reports. 23(10)
Hematopoietic stem cells (HSCs) cultured outside the body are the fundamental component of a wide range of cellular and gene therapies. Recent efforts have achieved > 200-fold expansion of functional HSCs, but their molecular characterization has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ac877a09594920e6043861938f91ea
https://pubmed.ncbi.nlm.nih.gov/35971894
https://pubmed.ncbi.nlm.nih.gov/35971894
Autor:
Liberalis Debraj Boila, Subhadeep Ghosh, Subham K. Bandyopadhyay, Liqing Jin, Alex Murison, Andy G. X. Zeng, Wasim Shaikh, Satyaki Bhowmik, Siva Sai Naga Anurag Muddineni, Mayukh Biswas, Sayantani Sinha, Shankha Subhra Chatterjee, Nathan Mbong, Olga I. Gan, Anwesha Bose, Sayan Chakraborty, Andrea Arruda, James A. Kennedy, Amanda Mitchell, Eric R. Lechman, Debasis Banerjee, Michael Milyavsky, Mark D. Minden, John E. Dick, Amitava Sengupta
Acute myeloid leukemia (AML) is a heterogeneous, aggressive malignancy with dismal prognosis and with limited availability of targeted therapies. AML exhibits epigenetic deregulation and transcriptional plasticity that contributes to pathogenesis. KD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8671514962a0aa21f6843bb9eeab906
https://doi.org/10.1101/2022.07.12.498585
https://doi.org/10.1101/2022.07.12.498585
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Diffuse Large B-Cell Lymphoma (DLBCL) is an aggressive hematological cancer for which mitochondrial metabolism may play an important role. Mitochondrial DNA (mtDNA) encodes crucial mitochondrial proteins, yet the relationship between mtDNA and DLBCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688726ce5c15588697aeed71290f78c0
https://doi.org/10.1038/s41598-018-21844-6
https://doi.org/10.1038/s41598-018-21844-6
Autor:
Andy G. X. Zeng, Karla L. Bretherick, Nina Thiessen, Lauren C. Tindale, Angela Brooks-Wilson, Stephen Leach
Publikováno v:
Gerontology. 62:58-62
Background: It is not understood whether long-term good health is promoted by the absence of disease risk variants, the presence of protective variants, or both. We characterized the exomes of two exceptionally healthy centenarian brothers aged 106 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932a93d41ce575085ed8050fb76f71d1
https://doi.org/10.1159/000430462
https://doi.org/10.1159/000430462