Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Andy C. Lee"'
Autor:
Michelle M. Hill, Debottam Sinha, Keshava K Datta, Xue Lu, Jiri Neuzil, Mriga Dutt, Murugan Kalimutho, Priyakshi Kalita-de Croft, Normand Pouliot, Prahlad V. Raninga, Harsha Gowda, Kum Kum Khanna, Lan-Feng Dong, Andy C Lee
Publikováno v:
Theranostics
Purpose: Lacking effective targeted therapies, triple-negative breast cancer (TNBCs) is highly aggressive and metastatic disease, and remains clinically challenging breast cancer subtype to treat. Despite the survival dependency on the proteasome pat
Autor:
Philip A. Erwin, Andy C. Lee, Usman Ahmad, Mara Antonoff, Andrew Arndt, Leah Backhus, Mark Berry, Thomas Birdas, Stephen D. Cassivi, Andrew C. Chang, David T. Cooke, Traves Crabtree, Malcolm DeCamp, Jessica Donington, Felix Fernandez, Seth Force, Henning Gaissert, Wayne Hofstetter, James Huang, Michael Kent, Anthony W. Kim, Jules Lin, Linda W. Martin, Shari Meyerson, John D. Mitchell, Daniela Molena, David Odell, Mark Onaitis, Varun Puri, Joe B. Putnam, Rishindra Reddy, Paul Schipper, Christopher W. Seder, Joseph Shrager, Betty Tong, Nirmal Veeramachaneni, Thomas Watson, Richard Whyte, Mark K. Ferguson
Publikováno v:
The Annals of thoracic surgery. 114(5)
Despite demonstration of its clear benefits relative to open approaches, a video-assisted thoracic surgery technique for pulmonary lobectomy has not been universally adopted. This study aims to overcome potential barriers by establishing the essentia
Autor:
Yu-Yin Shih, Wen-Ming Hsu, Ji-Hong Hong, Yung-Feng Liao, Fanfan Zhou, Andy C Lee, Tsi-Chian Chao, Hsinyu Lee
Publikováno v:
Journal of Molecular Medicine. 97:325-339
Oncogenic N-MYC (MYCN) is widely used as a biomarker in clinics for neuroblastoma (NB) patients; nevertheless, mechanism that underlines MYCN regulation remains elusive. In the present study, we identified calreticulin (CRT) as a novel MYCN suppresso
Autor:
Jen-Chine Wu, Hui-Ling Yeo, Ruey-Jen Lin, Tai-Yu Lai, Nai-Chuan Chang, Guo-Shiou Liao, Ching-Liang Ho, I-Ju Chen, Alice L. Yu, Andy C Lee
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-12 (2019)
Cell death discovery, vol 5, iss 1
Cell Death Discovery
Cell death discovery, vol 5, iss 1
Cell Death Discovery
FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer.
Autor:
Kathryn F. Tonissen, Debottam Sinha, Ashwini Makhale, Prahlad V. Raninga, Amanda L. Bain, Devathri Nanayakarra, Kum Kum Khanna, Murugan Kalimutho, Andy C Lee, Deepak Mittal, Yu-Yin Shih
Publikováno v:
International journal of cancerReferences. 146(1)
Triple-negative breast cancer (TNBCs) is a very aggressive and lethal form of breast cancer with no effective targeted therapy. Neoadjuvant chemotherapies and radiotherapy remains a mainstay of treatment with only 25-30% of TNBC patients responding.
Autor:
Nai-Chuan Chang, Andy C Lee, I-Ju Chen, Hui Ming Yu, John Yu, Te-Wei Lee, Alice L. Yu, Han-Chung Wu, Sheng-Hung Wang, Ya-Jen Chang, Jyh-Cherng Yu
Publikováno v:
Biomaterials. 94:31-44
It is more challenging to design peptide drugs than small molecules through molecular docking and in silico analysis. Here, we developed a structure-based approach with various computational and analytical techniques to optimize cancer-targeting pept
Autor:
Fang-Hsin Chen, Ching-Fang Yu, Chi-Dung Yang, Hsien Da Huang, Andy C Lee, Wei-Hsiang Kung, Yu-Chen Liu
Publikováno v:
Computational biology and chemistry. 69
Radiotherapy (RT) is a common cancer treatment approach that accounts for nearly 50% of patient treatment; however, tumor relapse after radiotherapy is still a major issue. To study the crucial role of tumor-associated macrophages (TAMs) in the regul
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 102:e190-e191
Autor:
K. K. Khanna, Y.-Y. Shin, Debottam Sinha, Prahlad V. Raninga, Andy C Lee, Deepak Mittal, Murugan Kalimutho
Publikováno v:
Annals of Oncology. 30:v3
Background Triple-negative breast cancers (TNBCs) are very aggressive and lethal forms of breast cancer with no effective targeted therapy. TNBCs spontaneously metastasize to distant organs including lungs, bone, and brain. Neo-adjuvant chemotherapie
Publikováno v:
British Journal of Pharmacology. 162:1380-1388
BACKGROUND AND PURPOSE The human organic anion transporting polypeptide 1A2 (OATP1A2) is expressed in cells from several regions of the human body, including the kidney, cholangiocytes and the blood-brain barrier, and mediates the cellular flux of va