Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Andy, Wullaert"'
Autor:
Hannah Stocks, Elisabeth De Leeuw, Bart N. Lambrecht, Linos Vandekerckhove, Geert van Loo, Andy Wullaert
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundDysregulated innate immune responses underlie multiple inflammatory diseases, but clinical translation of preclinical innate immunity research in mice is hampered by the difficulty of studying human inflammatory reactions in an in vivo cont
Externí odkaz:
https://doaj.org/article/cc23fd94c5e84069976b292763983fed
Autor:
Ioanna Petta, Marie Thorp, Maarten Ciers, Gillian Blancke, Louis Boon, Tim Meese, Filip Van Nieuwerburgh, Andy Wullaert, Richard Grencis, Dirk Elewaut, Geert van Loo, Lars Vereecke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundProtective immunity against intestinal helminths requires induction of robust type-2 immunity orchestrated by various cellular and soluble effectors which promote goblet cell hyperplasia, mucus production, epithelial proliferation, and smoo
Externí odkaz:
https://doaj.org/article/4430a9dec9a04b37b1e9e9b55eb09f9c
Autor:
Karel F. A. Van Damme, Pieter Hertens, Arne Martens, Elisabeth Gilis, Dario Priem, Inge Bruggeman, Amelie Fossoul, Jozefien Declercq, Helena Aegerter, Andy Wullaert, Tino Hochepied, Esther Hoste, Lieselotte Vande Walle, Mohamed Lamkanfi, Savvas N. Savvides, Dirk Elewaut, Bart N. Lambrecht, Geert van Loo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract A20 serves as a critical brake on NF-κB-dependent inflammation. In humans, polymorphisms in or near the TNFAIP3/A20 gene have been linked to various inflammatory disorders, including systemic lupus erythematosus (SLE) and rheumatoid arthrit
Externí odkaz:
https://doaj.org/article/0bf2e4c99bae45e2afbc4924a4035aa2
Autor:
Elien Eeckhout, Tomoko Asaoka, Hanne Van Gorp, Dieter Demon, Charlotte Girard-Guyonvarc’h, Vanessa Andries, Lars Vereecke, Cem Gabay, Mohamed Lamkanfi, Geert van Loo, Andy Wullaert
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundAutoinflammation with infantile enterocolitis (AIFEC) is an often fatal disease caused by gain-of-function mutations in the NLRC4 inflammasome. This inflammasomopathy is characterized by macrophage activation syndrome (MAS)-like episodes as
Externí odkaz:
https://doaj.org/article/22257ef24119463f84ae7fbc3bf11db2
Autor:
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)
Abstract Citrobacter rodentium is an enteropathogen that causes intestinal inflammatory responses in mice reminiscent of the pathology provoked by enteropathogenic and enterohemorrhagic Escherichia coli infections in humans. C. rodentium expresses va
Externí odkaz:
https://doaj.org/article/5979f518de434555b00d37dbbe8ecd50
Autor:
Karolina Slowicka, Inmaculada Serramito-Gómez, Emilio Boada-Romero, Arne Martens, Mozes Sze, Ioanna Petta, Hanna K. Vikkula, Riet De Rycke, Eef Parthoens, Saskia Lippens, Savvas N. Savvides, Andy Wullaert, Lars Vereecke, Felipe X. Pimentel-Muiños, Geert van Loo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Maintaining the intestinal barrier function requires a balance of multiple signalling pathways. Here the authors show that A20, an anti-inflammatory and anti-apoptotic protein, and Atg1611, an autophagy regulator, cross-regulate their respective prot
Externí odkaz:
https://doaj.org/article/66f4ba80a7fd4950b7b10906aec986dc
Autor:
Michail Mamantopoulos, Ulrika C. Frising, Tomoko Asaoka, Geert van Loo, Mohamed Lamkanfi, Andy Wullaert
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Vibrio cholerae is a Gram-negative enteropathogen causing potentially life-threatening cholera disease outbreaks, for which the World Health Organization currently registers 2–4 million cases and ~100.000 cholera-associated deaths annually worldwid
Externí odkaz:
https://doaj.org/article/fac12d995d5d42a0b4f5da1796ea0973
Autor:
Hanne Dubois, Frederic Sorgeloos, Soroush T Sarvestani, Liesbet Martens, Yvan Saeys, Jason M Mackenzie, Mohamed Lamkanfi, Geert van Loo, Ian Goodfellow, Andy Wullaert
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007709 (2019)
Norovirus infection is the leading cause of food-borne gastroenteritis worldwide, being responsible for over 200,000 deaths annually. Studies with murine norovirus (MNV) showed that protective STAT1 signaling controls viral replication and pathogenes
Externí odkaz:
https://doaj.org/article/a5e5350e08ed4b97b673e9f53edd4c1b
Autor:
Ona Rogiers, Ulrika C. Frising, Soňa Kucharíková, Mary Ann Jabra-Rizk, Geert van Loo, Patrick Van Dijck, Andy Wullaert
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Candida albicans is an opportunistic fungal pathogen that can cause life-threatening infections, particularly in immunocompromised patients. C. albicans induced activation of the Nlrp3 inflammasome, leading to secretion of bioactive interleu
Externí odkaz:
https://doaj.org/article/91d7d7e56ef642aeae005f9ab147cfa5
Autor:
Damya Laoui, Jo A. Van Ginderachter, Mohamed Lamkanfi, Andy Wullaert, Alain Beschin, Massimiliano Mazzone, Diether Lambrechts, Geert van Loo, Geert Raes, Louis Boon, Amelie Fossoul, Ayla Debraekeleer, Jan Brughmans, Maryse Schmoetten, Yvon Elkrim, Sana M. Arnouk, Pauline M.R. Bardet, Jiri Keirsse, Evangelia Bolli, Samantha Pretto, Manuel Ehling, Junbin Qian, Aleksandar Murgaski, Helena Van Damme, Els Lebegge, Pedro H.V. Saavedra, Lieselotte Vande Walle, Máté Kiss
Supplementary Figures 1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac555aa6d9d63833368748b3be0a555
https://doi.org/10.1158/2326-6066.22543494
https://doi.org/10.1158/2326-6066.22543494