Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Andy, McShea"'
Autor:
Karl Maurer, John Cooper, Marcelo Caraballo, James Crye, Dominic Suciu, Andrey Ghindilis, Joseph A Leonetti, Wei Wang, Francis M Rossi, Axel G Stöver, Christopher Larson, Hetian Gao, Kilian Dill, Andy McShea
Publikováno v:
PLoS ONE, Vol 1, p e34 (2006)
An addressable electrode array was used for the production of acid at sufficient concentration to allow deprotection of the dimethoxytrityl (DMT) protecting group from an overlaying substrate bound to a porous reaction layer. Containment of the gener
Externí odkaz:
https://doaj.org/article/d3e37e3c59a54ee48e1a263a72d01e3b
Autor:
Karen Bernards, Axel G. Stöver, Kevin R. Schwarzkopf, Kristian M. Roth, Andy McShea, Sandra B. Munro, Michael J. Lodes, Kia Peyvan, Maria W. Smith, Kilian Dill, Andrey L. Ghindilis
Publikováno v:
Biosensors and Bioelectronics. 22:1853-1860
Electrochemical detection has been developed and assay performances studied for the CombiMatrix oligonucleotide microarray platform that contains 12,544 individually addressable microelectrodes (features) in a semiconductor matrix. The approach is ba
Autor:
Andy McShea, Robin Hui Liu, Michael Bizak, David Danley, Sandra B. Munro, Tony Siuda, Tai Nguyen, Dominic Suciu, Mike Slota, H. Sho Fuji
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 11:360-367
The ongoing threat of the potential use of biothreat agents (such as Bacillus anthracis) as a biochemical weapon emphasizes the need for a rapid, miniature, fully automated, and highly specific detection assay. An integrated and self-contained microf
Autor:
Mark Elliot, Shane T. Grey, Andrew O. Yam, Eliana Mariño, Mariya W. Smith, Stacy N. Walters, David Liuwantara, Andy McShea
Publikováno v:
Diabetes. 55:2491-2501
Apoptotic β-cell death is central to the pathogenesis of type 1 diabetes and may be important in islet graft rejection. Despite this, genetic control of β-cell apoptosis is only poorly understood. We report that inhibition of gene transcription sen
Autor:
Michael J. Lodes, Robin Hui Liu, Mike Slota, H. Sho Fuji, Tony Siuda, Tai Nguyen, Andy McShea
Publikováno v:
Analytical Chemistry. 78:4184-4193
Rapid detection and identification of influenza virus is becoming increasingly important in the face of concerns over an influenza pandemic. A fully integrated and self-contained microfluidic device has been developed to rapidly identify influenza A
Autor:
Robin Hui Liu, Kevin R. Schwarzkopf, Michael Bizak, Alla Petrova, H. Sho Fuji, Andy McShea, Tony Siuda, Tai Nguyen, Kia Peyvan, David Danley
Publikováno v:
Analytical Chemistry. 78:1980-1986
A DNA microarray with 12,000 features was integrated with a microfluidic cartridge to automate the fluidic handling steps required to carry out a gene expression study of the human leukemia cell line (K562). The fully integrated microfluidic device c
Autor:
Andy McShea, Kilian Dill
Publikováno v:
Drug Discovery Today: Technologies. 2:261-266
An overview is presented for the current DNA-based microarray market, including applications for microarrays in areas such as gene expression, single-nucleotide polymorphism, strain differentiation, de novo DNA synthesis, aptamers and advances in 'in
Publikováno v:
Journal of Combinatorial Chemistry. 7:637-640
Publikováno v:
Journal of the American Chemical Society. 128(50)
Time-of-flight secondary ion mass spectrometry (TOF SIMS) has been used in conjunction with a mass spectrometry cleavable linker to determine the percent conversion of reactions that were conducted site-selectively on an addressable microelectrode ar
Autor:
David, Liuwantara, Mark, Elliot, Mariya W, Smith, Andrew O, Yam, Stacy N, Walters, Eliana, Marino, Andy, McShea, Shane T, Grey
Publikováno v:
Diabetes. 55(9)
Apoptotic beta-cell death is central to the pathogenesis of type 1 diabetes and may be important in islet graft rejection. Despite this, genetic control of beta-cell apoptosis is only poorly understood. We report that inhibition of gene transcription