Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Andrzej Z. Wasilczuk"'
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2022)
Previous studies have demonstrated that the brain has an intrinsic resistance to changes in arousal state. This resistance is most easily measured at the population level in the setting of general anesthesia and has been termed neural inertia. To dat
Externí odkaz:
https://doaj.org/article/dfe8a02973d54106aca0b6c7b196b717
Autor:
Andrew R. McKinstry-Wu, Andrzej Z. Wasilczuk, William P. Dailey, Roderic G. Eckenhoff, Max B. Kelz
Publikováno v:
The Journal of Neuroscience. 43:2338-2348
Photoaffinity ligands are best known as tools used to identify the specific binding sites of drugs to their molecular targets. However, photoaffinity ligands have the potential to further define critical neuroanatomic targets of drug action. In the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eeabb00f96dbaf20c8b591ada6b2f8c
https://doi.org/10.1523/jneurosci.1884-22.2023
https://doi.org/10.1523/jneurosci.1884-22.2023
Autor:
Andrew R McKinstry-Wu, Andrzej Z Wasilczuk, Benjamin A Harrison, Victoria M Bedell, Mathangi J Sridharan, Jayce J Breig, Michael Pack, Max B Kelz, Alexander Proekt
Publikováno v:
eLife, Vol 8 (2019)
Traditionally, drug dosing is based on a concentration-response relationship estimated in a population. Yet, in specific individuals, decisions based on the population-level effects frequently result in over or under-dosing. Here, we interrogate the
Externí odkaz:
https://doaj.org/article/4213c79618d14c70a26b18d0e1174344
Autor:
Joseph Cichon, Andrzej Z. Wasilczuk, Loren L. Looger, Diego Contreras, Max B. Kelz, Alex Proekt
Publikováno v:
Nature Neuroscience. 26:39-52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f23ec54301ac37121bf908bcd8b0944b
https://doi.org/10.1038/s41593-022-01203-5
https://doi.org/10.1038/s41593-022-01203-5
Autor:
Joseph, Cichon, Andrzej Z, Wasilczuk, Loren L, Looger, Diego, Contreras, Max B, Kelz, Alex, Proekt
Publikováno v:
Nature neuroscience.
The brain can become transiently disconnected from the environment while maintaining vivid, internally generated experiences. This so-called 'dissociated state' can occur in pathological conditions and under the influence of psychedelics or the anest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca07c8d8589d83b6261bb2218d84212e
https://pubmed.ncbi.nlm.nih.gov/36424433
https://pubmed.ncbi.nlm.nih.gov/36424433
Autor:
Bo Ku, Max B. Kelz, Andrzej Z. Wasilczuk, Paula Kwasniewska, Andrew R. McKinstry-Wu, Benjamin A Harrison, Alex Proekt
Publikováno v:
British journal of anaesthesia. 125(3)
Background Recent studies point to a fundamental distinction between population-based and individual-based anaesthetic pharmacology. At the population level, anaesthetic potency is defined as the relationship between drug concentration and the likeli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4f7c1f3642c9f86e4d19832ba2b4a8
https://pubmed.ncbi.nlm.nih.gov/32654746
https://pubmed.ncbi.nlm.nih.gov/32654746
Autor:
Max B. Kelz, Jayce J Breig, Mathangi Sridharan, Victoria M Bedell, Andrew R. McKinstry-Wu, Andrzej Z. Wasilczuk, Michael Pack, Alex Proekt, Benjamin A Harrison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0097f29b67523cb7430d5be3f781c5a2
https://doi.org/10.7554/elife.50143.sa2
https://doi.org/10.7554/elife.50143.sa2
Publikováno v:
Curr Biol
Summary Endogenous sleep and general anesthesia are distinct states that share similar traits. Of particular interest to neuroscience is the loss of consciousness that accompanies both states. Multiple lines of evidence demonstrate that general anest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930cbc3249cab6360dd7fa3b6379e01b
https://doi.org/10.1016/j.cub.2020.10.050
https://doi.org/10.1016/j.cub.2020.10.050
Publikováno v:
Sleep. 43:A63-A63
Introduction The hypothalamic preoptic area (POA) is a heterogeneous region of the brain, containing intermingled populations of excitatory and inhibitory neurons expressing a wide variety of molecular markers. Of its many important homeostatic roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea39ad7793d0af71bb649c7e84d8f568
https://doi.org/10.1093/sleep/zsaa056.158
https://doi.org/10.1093/sleep/zsaa056.158
The mouse has been used in many medical fields as a powerful model to reveal the genetic basis of human physiology and disease. The past two decades have witnessed an enormous wealth of genetic and informatic resources dedicated to this humble organi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a2f024dbf99c322a8039827cb2f3da
https://doi.org/10.1016/bs.mie.2018.01.008
https://doi.org/10.1016/bs.mie.2018.01.008