Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Andrzej W Cwetsch"'
Autor:
Andrzej W Cwetsch, Javier Gilabert-Juan, Sofia Ferreira, Matthieu Moreau, Yoann Saillour, Elodie Delberghe, Jose González Martínez, Stephen Nedelec, Ugo Borello, Sophie Thomas, Frederic Causeret, Alessandra Pierani
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S85- (2023)
Externí odkaz:
https://doaj.org/article/5df3f6d6258b438c9fe35502cc08bfdd
Autor:
Francesco Trovato, Riccardo Parra, Enrico Pracucci, Silvia Landi, Olga Cozzolino, Gabriele Nardi, Federica Cruciani, Vinoshene Pillai, Laura Mosti, Andrzej W. Cwetsch, Laura Cancedda, Laura Gritti, Carlo Sala, Chiara Verpelli, Andrea Maset, Claudia Lodovichi, Gian Michele Ratto
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Genetic mosaicism is frequently present in monogenic diseases of the central nervous system. Here the authors design a dual-colour reporter system that can be used to tune the degree of mosaicism in mouse models.
Externí odkaz:
https://doaj.org/article/1c4e916eb6864c37acafbefd423dd53f
Autor:
José González-Martínez, Andrzej W. Cwetsch, Diego Martínez-Alonso, Luis R. López-Sainz, Jorge Almagro, Anna Melati, Jesús Gómez, Manuel Pérez-Martínez, Diego Megías, Jasminka Boskovic, Javier Gilabert-Juan, Osvaldo Graña-Castro, Alessandra Pierani, Axel Behrens, Sagrario Ortega, Marcos Malumbres
Publikováno v:
JCI Insight, Vol 6, Iss 16 (2021)
Congenital microcephaly (MCPH) is a neurodevelopmental disease associated with mutations in genes encoding proteins involved in centrosomal and chromosomal dynamics during mitosis. Detailed MCPH pathogenesis at the cellular level is still elusive, gi
Externí odkaz:
https://doaj.org/article/35053144b6b7492e9888936049f5061b
Autor:
Shovan Naskar, Roberto Narducci, Edoardo Balzani, Andrzej W. Cwetsch, Valter Tucci, Laura Cancedda
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The development of functional synapses is a key milestone in neurodevelopment. Here, the authors show how serotonin signalling coordinates development of glutamatergic and GABAergic currents and triggers the emergence of integrative behavior (huddlin
Externí odkaz:
https://doaj.org/article/3d0fe1f30a8a4aec868747c155d9b87e
Autor:
Yoko Arai, Andrzej W. Cwetsch, Eva Coppola, Sara Cipriani, Hidenori Nishihara, Hiroaki Kanki, Yoann Saillour, Betty Freret-Hodara, Annie Dutriaux, Norihiro Okada, Hideyuki Okano, Colette Dehay, Jeannette Nardelli, Pierre Gressens, Tomomi Shimogori, Giuseppe D’Onofrio, Alessandra Pierani
Publikováno v:
Cell Reports, Vol 29, Iss 3, Pp 645-658.e5 (2019)
Summary: Changes in transcriptional regulation through cis-regulatory elements are thought to drive brain evolution. However, how this impacts the identity of primate cortical neurons is still unresolved. Here, we show that primate-specific cis-regul
Externí odkaz:
https://doaj.org/article/353a94f555f14560af0800ea6cb2f9cc
Autor:
Federica Cruciani, Enrico Pracucci, Laura Gritti, Laura Cancedda, Laura Mosti, Silvia Landi, Olga Cozzolino, Claudia Lodovichi, Riccardo Parra, Carlo Sala, Chiara Verpelli, Francesco Trovato, Gabriele Nardi, Vinoshene Pillai, Andrzej W. Cwetsch, Andrea Maset, Gian Michele Ratto
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature communications 11 (2020). doi:10.1038/s41467-020-19864-w
info:cnr-pdr/source/autori:Trovato F.; Parra R.; Pracucci E.; Landi S.; Cozzolino O.; Nardi G.; Cruciani F.; Pillai V.; Mosti L.; Cwetsch A.W.; Cancedda L.; Gritti L.; Sala C.; Verpelli C.; Maset A.; Lodovichi C.; Ratto G.M./titolo:Modelling genetic mosaicism of neurodevelopmental disorders in vivo by a Cre-amplifying fluorescent reporter/doi:10.1038%2Fs41467-020-19864-w/rivista:Nature communications/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Nature Communications
Nature communications 11 (2020). doi:10.1038/s41467-020-19864-w
info:cnr-pdr/source/autori:Trovato F.; Parra R.; Pracucci E.; Landi S.; Cozzolino O.; Nardi G.; Cruciani F.; Pillai V.; Mosti L.; Cwetsch A.W.; Cancedda L.; Gritti L.; Sala C.; Verpelli C.; Maset A.; Lodovichi C.; Ratto G.M./titolo:Modelling genetic mosaicism of neurodevelopmental disorders in vivo by a Cre-amplifying fluorescent reporter/doi:10.1038%2Fs41467-020-19864-w/rivista:Nature communications/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Genetic mosaicism, a condition in which an organ includes cells with different genotypes, is frequently present in monogenic diseases of the central nervous system caused by the random inactivation of the X-chromosome, in the case of X-linked patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0872dbe5de270bc2a8827c2bfb7ef27
https://doaj.org/article/1c4e916eb6864c37acafbefd423dd53f
https://doaj.org/article/1c4e916eb6864c37acafbefd423dd53f
Autor:
Andrzej W. Cwetsch, Ilias Ziogas, Roberto Narducci, Annalisa Savardi, Maria Bolla, Bruno Pinto, Laura E. Perlini, Silvia Bassani, Maria Passafaro, Laura Cancedda
Publikováno v:
Brain communications. 4(3)
Protocadherin 19 gene-related epilepsy or protocadherin 19 clustering epilepsy is an infantile-onset epilepsy syndrome characterized by psychiatric (including autism-related), sensory, and cognitive impairment of varying degrees. Protocadherin 19 clu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6009f046d26f5b72fea6a6cdc4ddd5ae
https://pubmed.ncbi.nlm.nih.gov/35528232
https://pubmed.ncbi.nlm.nih.gov/35528232
Autor:
José González-Martínez, Andrzej W. Cwetsch, Javier Gilabert-Juan, Jesús Gómez, Guillermo Garaulet, Paulina Schneider, Guillermo de Cárcer, Francisca Mulero, Eduardo Caleiras, Diego Megías, Eva Porlan, Marcos Malumbres
Publikováno v:
Cell Death and Differentiation 29: 1474-1485 (2022).
Alteration of centrosome function and dynamics results in major defects during chromosome segregation and is associated with primary autosomal microcephaly (MCPH). Despite the knowledge accumulated in the last few years, why some centrosomal defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728a0b0363e13c123b6e0e84a64146d5
http://hdl.handle.net/10261/283827
http://hdl.handle.net/10261/283827
Autor:
Alessandra Pierani, Sagrario Ortega, Andrzej W. Cwetsch, Jorge Almagro, Diego Martínez-Alonso, Osvaldo Graña-Castro, Jesús Gómez, Axel Behrens, Marcos Malumbres, Diego Megías, Manuel Pérez-Martínez, Anna Melati, José González-Martínez, Luis R. López-Sainz, Jasminka Boskovic, Javier Gilabert-Juan
Publikováno v:
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2021, 6 (16), pp.e146364. ⟨10.1172/jci.insight.146364⟩
JCI Insight, American Society for Clinical Investigation, 2021, 6 (16), pp.e146364. ⟨10.1172/jci.insight.146364⟩
Congenital microcephaly (MCPH) is a neurodevelopmental disease associated to mutations in genes encoding proteins involved in centrosomal and chromosomal dynamics during mitosis. Detailed MCPH pathogenesis at the cellular level is still elusive given
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b67f9b885e753a0d5c1b965fc0d0f7a
Autor:
Laura E. Perlini, Bruno Pinto, Laura Cancedda, Andrzej W. Cwetsch, Roberto Narducci, Maria Bolla, Silvia Bassani, Maria Passafaro
PCDH19 gene-related epilepsy or epileptic encephalopathy, early infantile, 9 (EIEE9) is an infantile onset epilepsy syndrome characterized by psychiatric (including autistic) sensory and cognitive impairment of varying degrees. EIEE9 is caused by X-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c67da3438ed848d41a3742a25b497226
https://doi.org/10.1101/2020.06.12.145508
https://doi.org/10.1101/2020.06.12.145508