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Autor:
Elizabeth Alice Mathews, M. Szelke, Andrzej R Batt, David P Rooker, Hamish Ryder, David A Kendrick, Graeme Semple
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:867-872
Replacement of the C-terminal dipeptide amide of Boc-CCK-4 (1) with oxopiperazines yields a series of weak CCK-receptor ligands. Further modifications result in more potent and receptor subtype selective compounds.