Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Andrzej Pankowski"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Substitution of lysine 27 with methionine in histone H3.3 (H3.3K27M) is a driver mutation of pediatric high-grade gliomas. Here the authors show that H3.3K27M-mediated alterations in H3K27me3 distribution result in ectopic DNA replication and cell cy
Externí odkaz:
https://doaj.org/article/15ff841362f0489ca570360241b3e7f6
Substitution of lysine 27 with methionine in histone H3.3 is a recently discovered driver mutation of pediatric high-grade gliomas. Mutant tumor cells show decreased levels and altered distribution of H3K27me3. How these chromatin changes are establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9d5ed2b87747cdd626d21872144b74