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pro vyhledávání: '"Andrzej M. Trocha"'
Autor:
Irina S. Zemtseva, Michael E. Augustyniak, Allison M. Martino, Richard A. Earl, Delano V. Young, L. Gordon Letts, Madhavi G. Murty, Matthew J. Shumway, David S. Garvey, David J. Schwalb, Subhash P. Khanapure, Andrzej M. Trocha, David R. Janero
Publikováno v:
Journal of Medicinal Chemistry. 48:3930-3934
Incorporation of a spacer group between the central scaffold and the aryl ring resulted in a new cyclooxygenase-2 (COX-2) selective inhibitor core structure, 3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) phenyl ketone (20), with COX-2 I