Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Andrzej M Janczewski"'
Autor:
Ferhaan Ahmad, Sanjay K Banerjee, Michele L Lage, Xueyin N Huang, Stephen H Smith, Samir Saba, Jennifer Rager, David A Conner, Andrzej M Janczewski, Kimimasa Tobita, Joseph P Tinney, Ivan P Moskowitz, Antonio R Perez-Atayde, Bradley B Keller, Michael A Mathier, Sanjeev G Shroff, Christine E Seidman, J G Seidman
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2642 (2008)
Hypertrophic (HCM) and dilated (DCM) cardiomyopathies result from sarcomeric protein mutations, including cardiac troponin T (cTnT, TNNT2). We determined whether TNNT2 mutations cause cardiomyopathies by altering cTnT function or quantity; whether th
Externí odkaz:
https://doaj.org/article/cd3d3ebeca6e44d79a325dd4ab1ab7e6
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2449 (2017)
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2449 (2017)
Chronic obstructive pulmonary disease (COPD) is a major global cause of morbidity and mortality, projected to become the 3rd cause of disease mortality worldwide by 2020. COPD is characterized by persistent and not fully reversible airflow limitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca9a512154fa9627509ac0a35baf210
https://pubmed.ncbi.nlm.nih.gov/29156550
https://pubmed.ncbi.nlm.nih.gov/29156550
Publikováno v:
Heart Failure Reviews. 15:431-445
Hypertension, atherosclerosis, and resultant chronic heart failure (HF) reach epidemic proportions among older persons, and the clinical manifestations and the prognoses of these worsen with increasing age. Thus, age per se is the major risk factor f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a99629ee55401443dde053e7bc5a49
https://doi.org/10.1007/s10741-010-9167-5
https://doi.org/10.1007/s10741-010-9167-5
Autor:
Donna B. Stolz, Joseph P. Tinney, Jill M. Nonemaker, Kimimasa Tobita, Andrzej M. Janczewski, Serena Augustine, Li J. Liu, Sanjeev G. Shroff, Bradley B. Keller
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H1829-H1837
Embryonic myocardium has a high rate of cell proliferation and regulates cellular proliferation, contractile function, and myocardial architecture in response to changes in external mechanical loads. However, the small and complex three-dimensional (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7281f62112354497ab6e083f1cb4b7ec
https://doi.org/10.1152/ajpheart.00205.2006
https://doi.org/10.1152/ajpheart.00205.2006
Autor:
Barry London, Guy Salama, Andrzej M. Janczewski, Samir Saba, Linda C. Baker, Vladimir Shusterman, Erdal Gursoy, Charles F. McTiernan, Arthur M. Feldman
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 289:H1456-H1467
Transgenic mice overexpressing the inflammatory cytokine TNF-α in the heart develop a progressive heart failure syndrome characterized by biventricular dilatation, decreased ejection fraction, decreased survival compared with non-transgenic litterma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003b78aa34e351385a2d428ab44a68e1
https://doi.org/10.1152/ajpheart.00733.2004
https://doi.org/10.1152/ajpheart.00733.2004
Publikováno v:
Journal of Molecular and Cellular Cardiology. 34:641-648
A. M. Janczewski, H. A. Spurgeon and E. G. Lakatta. Action Potential Prolongation in Cardiac Myocytes of Old Rats is an Adaptation to Sustain Youthful Intracellular Ca2+ Regulation. Journal of Molecular and Cellular Cardiology (2002) 34, 641–648. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70eb996e01e89fa48d1a577cd41e1c2a
https://doi.org/10.1006/jmcc.2002.2004
https://doi.org/10.1006/jmcc.2002.2004
Autor:
Chahrzad Montrose-Rafizadeh, Andrzej M. Janczewski, Steven J. Sollott, Marco A. Pineyro, Yihong Wang, Jie Zhou, Josephine M. Egan
Publikováno v:
Journal of Cellular Physiology. 181:470-478
In this study, AR42J pancreatic acinar cells were used to investigate if glucagon-like peptide-1 (GLP-1) or glucagon might influence amylase release and acinar cell function. We first confirmed the presence of GLP-1 receptors on AR42J cells by revers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef6399d77139d859e410d527f9c11dc7
https://doi.org/10.1002/(sici)1097-4652(199912)181:3<470::aid-jcp11>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199912)181:3<470::aid-jcp11>3.0.co
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 265:H517-H522
We examined the effects of thapsigargin on Ca2+ accumulation by the sarcoplasmic reticulum (SR) and on electrically stimulated beats in single adult rat ventricular myocytes loaded with indo 1 and bathed in N-2-hydroxyethylpiperazine-N'-2-ethanesulfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae9ea885053e0f893d992c64f05961d
https://doi.org/10.1152/ajpheart.1993.265.2.h517
https://doi.org/10.1152/ajpheart.1993.265.2.h517
Autor:
Charles F. McTiernan, Maliha Zahid, Evangelia G. Kranias, Carol S. Frye, Bonnie Lemster, Gregory A. Gibson, Yoshihiro Higuchi, Arthur M. Feldman, Andrzej M. Janczewski
Publikováno v:
Cardiovascular research. 62(3)
Decreased amplitude and slower kinetics of cardiomyocyte intracellular calcium (Cai2+) transients may underlie the diminished cardiac function observed in heart failure. These alterations occur in humans and animals with heart failure, including the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ff1689c6a84c84f3767c3a94ea20df
https://pubmed.ncbi.nlm.nih.gov/15158133
https://pubmed.ncbi.nlm.nih.gov/15158133
Publikováno v:
Europe PubMed Central
To determine the effect of voltage-independent alterations of L-type Ca2+ current ( I Ca) on the sarcoplasmic reticular (SR) Ca2+ release in cardiac myocytes, we measured I Ca and cytosolic Ca2+ transients (Cai 2+; intracellular Ca2+ concentration) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5adbb582a46b9d79fbdc3a2e69fb343
https://pubmed.ncbi.nlm.nih.gov/11009494
https://pubmed.ncbi.nlm.nih.gov/11009494