Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Andrzej Gardas"'
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 92:77-84
Autoantibodies to different thyroid cell components in serum of patients with thyroid disease have been estimated by several methods. The TSH receptor antibodies (TRAb) have been detected in 77% of untreated Graves-Basedow, in 70% of thionamide drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545aa44110bb2613fb23836b29e57005
https://doi.org/10.1055/s-0029-1210784
https://doi.org/10.1055/s-0029-1210784
Autor:
Brigitte Nguyen, Damien Bresson, J. Paul Banga, Sandra A. Rebuffat, Andrzej Gardas, Sylvie Peraldi-Roux
Publikováno v:
Endocrinology. 146:2834-2844
Human anti-thyroperoxidase (TPO) autoantibodies (aAbs) are a major hallmark of autoimmune thyroid diseases. Their epitopes are discontinuous and mainly restricted to an immunodominant region (IDR) consisting of two overlapping regions (IDR/A and B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdfe7ab06e118eb0ba791827965bba90
https://doi.org/10.1210/en.2005-0038
https://doi.org/10.1210/en.2005-0038
Autor:
Yi-chi M. Kong, Qiang Wan, J. P. Banga, Monika Gora, Chella S. David, G. Alsharabi, Wei Zen Wei, Alvaro A. Giraldo, Andrzej Gardas, Jeffrey C. Flynn
Publikováno v:
Clinical and Experimental Immunology. 137:503-512
SUMMARYMurine experimental autoimmune thyroiditis (EAT), characterized by thyroid destruction after immunization with thyroglobulin (Tg), has long been a useful model of organ-specific autoimmune disease. More recently, porcine thyroid peroxidase (pT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e031d49b04c3b92d5a6b2055cdc3af6a
https://doi.org/10.1111/j.1365-2249.2004.02553.x
https://doi.org/10.1111/j.1365-2249.2004.02553.x
Autor:
Philip F. Watson, Brian J. Sutton, Anthony P. Weetman, Andrzej Gardas, Paul Hobby, Monika Gora, J. Paul Banga
Publikováno v:
Biochemical and Biophysical Research Communications. 320:795-801
Thyroid peroxidase (TPO) is a major autoantigen in thyroid autoimmune disease where pathogenic autoantibodies recognise conformational epitopes restricted to two overlapping immunodominant regions (IDR) termed IDR-A and -B. Based upon our structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875aee0974743501fa316c0d74f1869a
https://doi.org/10.1016/j.bbrc.2004.06.028
https://doi.org/10.1016/j.bbrc.2004.06.028
Publikováno v:
Autoimmunity. 37:211-216
Autoantibodies to thyroid peroxidase (TPO) predominately recognise conformational epitopes, restricted to two immunodominant regions (IDR) -A and -B. We have estimated the proportion of IDR-A and -B autoantibodies in 75 Hashimoto and 68 Graves patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fd3dab7ebd6df53aca1a29634aea34
https://doi.org/10.1080/0891693042000193339
https://doi.org/10.1080/0891693042000193339
Autor:
J. Paul Banga, Grażyna Adler, Urszula Piotrowska, Marek Kaniewski, Andrzej Gardas, Małgorzata Gietka-Czernel
Publikováno v:
Thyroid. 12:563-570
In a study designed to detect the presence of soluble, secreted A subunit of thyrotropin hormone receptor (TSHR) in serum, using anti-TSHR murine antibodies (mAbs) and peptide specific antiserum for Western blotting of human serum proteins fractionat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6029fec11a0593632dc4facee2ee036c
https://doi.org/10.1089/105072502320288401
https://doi.org/10.1089/105072502320288401
Publikováno v:
Endocrinology. 141:2018-2026
Autoimmune thyroid diseases (AITD) are characterized by the presence of autoantibodies to thyroid peroxidase (TPO). This response is dominated by autoantibodies to two conformational determinants, termed A and B, that have been defined by monoclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d6fda9cc696ec95fee8d53430113f2
https://doi.org/10.1210/endo.141.6.7506
https://doi.org/10.1210/endo.141.6.7506
Autor:
Philip F. Watson, R S McIntosh, Andrzej Gardas, J. Paul Banga, E. Helen Kemp, Anthony P. Weetman, M. Suhail Asghar
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:3818-3825
Antibodies (Ab) to thyroid peroxidase (TPO) are common in patients with autoimmune thyroid disease and may play a role in disease pathogenesis. We have prepared immunoglobulin G kappa (IgG kappa) and IgG lambda phage display combinatorial libraries f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::757bd18daefa5e26ba598fda76938c70
https://doi.org/10.1210/jcem.82.11.4348
https://doi.org/10.1210/jcem.82.11.4348
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:3752-3757
Thyroid peroxidase (TPO) is the key enzyme involved in the biosynthesis of thyroid hormones and is an important autoantigen in autoimmune thyroid disease. Different messenger RNA species coding for TPO are present in thyroid tissue, including the spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc75b07e2b0b0380a44234a119043a60
https://doi.org/10.1210/jcem.82.11.4335
https://doi.org/10.1210/jcem.82.11.4335
Autor:
Hanna Domek, Andrzej Gardas
Publikováno v:
Acta Biochimica Polonica. 40:237-240
The influence of iodine-iodide solution on the biochemical and immunological properties of human thyroglobulin (hTg) were studied. Human Tg preincubated with the iodine-iodide solution is split to small molecular mass fragments after disulphide bridg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc56084d9124bb2861da8ce4fc179c0
https://doi.org/10.18388/abp.1993_4824
https://doi.org/10.18388/abp.1993_4824