Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Andrzej Ejchart"'
Publikováno v:
Physical chemistry chemical physics : PCCP. 24(22)
Inclusion complexes of naphthalene (NP) with cyclodextrins (CD) have been investigated so far using non-NMR techniques resulting in inconsistent data. Here, the first application of high-field NMR spectroscopy in combination with a precise analysis o
Publikováno v:
Journal of Biomolecular NMR. 70:219-228
Simple and convenient method of protein dynamics evaluation from the insufficient experimental 15N relaxation data is presented basing on the ratios, products, and differences of longitudinal and transverse 15N relaxation rates obtained at a single m
Publikováno v:
Physical chemistry chemical physics : PCCP. 21(13)
Complex formation between quinine and natural cyclodextrins (CD) was studied using NMR spectroscopy. The strongest association was observed for complexes of neutral quinine molecules with βCD. Association constants for monocationic quinine were one
Autor:
Andrzej Ejchart, Anika Lasota, Aleksandra Misicka, Oliwia Frączak, Maciej Maciejczyk, Aleksandra Olma, Piotr Kosson, Michał Nowakowski
Publikováno v:
Journal of Peptide Science. 22:545-551
The synthesis of new dermorphin analogues is described. The (R)-alanine or phenylalanine residues of natural dermorphin were substituted by the corresponding α-methyl-β-azidoalanine or α-benzyl-β-azido(1-piperidinyl)alanine residues. The potency
Autor:
Oliwia Frączak, Michał Nowakowski, Aleksandra Olma, Anika Lasota, Maciej Maciejczyk, Andrzej Ejchart, Adriana Muchowska
Publikováno v:
Chemical Biology & Drug Design. 87:824-832
This article describes new deltorphin I analogs in which phenylalanine residues were replaced by the corresponding (R) or (S)-α-benzyl-β-azidoalanine, α-benzyl-β-(1-pyrrolidinyl)alanine, α-benzyl-β-(1-piperidinyl)alanine, and α-benzyl-β-(4-mo
Publikováno v:
The journal of physical chemistry / B 119(36), 11978-11987 (2015). doi:10.1021/acs.jpcb.5b07181
Journal of Physical Chemistry B
Journal of Physical Chemistry B
Nuclear magnetic relaxation provides a powerful method giving insight into molecular motions at atomic resolution on a broad time scale. Dynamics of biological macromolecules has been widely exploited by measuring (15)N and (13)C relaxation data. Int
Autor:
Benedykt Wladyka, Łukasz Jaremko, Andrzej Ejchart, Michał Nowakowski, Grzegorz Dubin, Paweł Mak
Publikováno v:
International journal of biological macromolecules. 107
BacSp222 is a multifunctional bacteriocin produced by Staphylococcus pseudintermedius strain 222, an opportunistic pathogen of domestic animals. At micromolar concentrations, BacSp222 kills Gram-positive bacteria and is cytotoxic toward mammalian cel
Publikováno v:
Chirality. 29(11)
Gibbs energies of complex formation between enantiomers of bicyclic terpenoid, fenchone, and naturally occurring cyclodextrins, βCD and γCD, were determined by means of 13 C and 1 H nuclear magnetic resonance (NMR) titration data. These results wer
Autor:
Aleksandra Olma, Anika Lasota, Andrzej Ejchart, Oliwia Frączak, Michał Nowakowski, Andrzej W. Lipkowski, Anna Leśniak, Adriana Muchowska
Publikováno v:
Journal of Peptide Science. 21:120-125
New analogues of deltorphin I (DT I, Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2 ), with the D-Ala residue in position 2 replaced by α-methyl-β-azido(amino, 1-pyrrolidinyl, 1-piperidinyl or 4-morpholinyl)alanine, were synthesized by a combination of solid-ph
Autor:
Łukasz Jaremko, Matthias Bochtler, Andrzej Ejchart, Michał Nowakowski, Mariusz Jaremko, Roman H. Szczepanowski, Marek Wojciechowski, Igor Zhukov, Renata Panecka
Publikováno v:
Journal of Structural Biology
Journal of structural biology 185(1), 69-78 (2014). doi:10.1016/j.jsb.2013.10.020
Journal of structural biology 185(1), 69-78 (2014). doi:10.1016/j.jsb.2013.10.020
We report a high resolution NMR structure and N-15 relaxation studies of the first catalytic cysteine halfdomain (FCCH) of the mouse ubiquitin-activating enzyme El, together with interaction studies of FCCH and the other catalytic El subdomain - SCCH