Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Andrzej E. Wróblewski"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1722-1757 (2019)
Since Garner’s aldehyde has several drawbacks, first of all is prone to racemization, alternative three-carbon chirons would be of great value in enantioselective syntheses of natural compounds and/or drugs. This review article summarizes applicati
Externí odkaz:
https://doaj.org/article/e3f96b7f57b44000abda0281f4c8d9c3
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 236-255 (2019)
Glutamic acid is involved in several cellular processes though its role as the neurotransmitter is best recognized. For detailed studies of interactions with receptors a number of structural analogues of glutamic acid are required to map their active
Externí odkaz:
https://doaj.org/article/435fe3d229be48a995a336981df800b5
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1722-1757 (2019)
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1722-1757 (2019)
Since Garner’s aldehyde has several drawbacks, first of all is prone to racemization, alternative three-carbon chirons would be of great value in enantioselective syntheses of natural compounds and/or drugs. This review article summarizes applicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946c422bf73fc9491d0987f25af9851b
http://europepmc.org/articles/PMC6664392
http://europepmc.org/articles/PMC6664392
Autor:
Graciela Andrei, Robert Snoeck, Dominique Schols, Andrzej E. Wróblewski, Dorota G. Piotrowska, Iwona E. Głowacka
Publikováno v:
Monatshefte Fur Chemie
To study the influence of a linker rigidity and changes in donor-acceptor properties, three series of nucleotide analogs containing a P-X-HN-C(O)- residue (X=CH(OH)CH2, CH(OH)CH2CH2, CH2CH(OH)CH2) as a replacement for the P-CH2-O-CHR- fragment in acy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fba27eeb330f3ac9fbab1a41afdc40
http://europepmc.org/articles/PMC7087949
http://europepmc.org/articles/PMC7087949
Autor:
Dominique Schols, Jan Balzarini, Robert Snoeck, Dorota G. Piotrowska, Joanna Gotkowska, Andrzej E. Wróblewski, Graciela Andrei
Publikováno v:
Tetrahedron
Isoxazolidine analogues of homonucleos(t)ides were synthesized from nucleobase-derived nitrones 20a-20e (uracil, 5-fluorouracil, 5-bromouracil, thymine, adenine) employing 1,3-dipolar cycloadditions with allyl alcohol as well as with alkenylphosphona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be94784f30ec9422cbbff5be8488d27e
https://doi.org/10.1016/j.tet.2016.10.073
https://doi.org/10.1016/j.tet.2016.10.073
Publikováno v:
Synlett. 26:375-379
The general and efficient method for the synthesis of 4-phosphonylated β-lactams from N-methyl-C-(diethoxyphosphonyl)nitrone and selected terminal alkynes via Kinugasa reaction was reported. Application of microwave irradiation significantly shorten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e684422576c227cdeb1fedbb699ea83
https://doi.org/10.1055/s-0034-1379506
https://doi.org/10.1055/s-0034-1379506
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 189:1237-1253
Enantiomerically pure orthogonally protected dimethyl 1-aminophosphonates (2R,5R,6R,1′R)- and (2R,5R,6R,1′S)-10, phosphonate analogs of 4-hydroxythreonine, were prepared employing the three-component reaction between trimethyl phosphite, (2R,5R,6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5b97ca1bb1ebd2d53956cc1dec989ef
https://doi.org/10.1080/10426507.2014.883624
https://doi.org/10.1080/10426507.2014.883624
Publikováno v:
Archiv der Pharmazie. 347:506-514
A new series of 4-substituted [(1,2,3-triazol-1-yl)acetamido]methylphosphonates as acyclic nucleotide analogs were synthesized from diethyl (2-chloroacetamido)methylphosphonate via azidation followed by 1,3-dipolar cycloaddition with selected alkynes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e162c2a196c76a366962614d1d99f82
https://doi.org/10.1002/ardp.201300468
https://doi.org/10.1002/ardp.201300468
Publikováno v:
Archiv der Pharmazie. 346:677-687
A novel series of phosphonylated 1,2,3-triazoles as structural acyclic analogs of ribavirin, in which the 1,2,3-triazole ring was substituted at C4' with COOMe, CONH2, CONHOH, and CH2 NHBoc groups, were synthesized from diethyl azidomethyl-, 2-azidoe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49dbbf1fb363cfda84fc04d5f55d8a6
https://doi.org/10.1002/ardp.201300156
https://doi.org/10.1002/ardp.201300156
Publikováno v:
Archiv der Pharmazie. 346:278-291
A general procedure for the preparation of 1,2,3-triazole analogs of nucleosides from diethyl 2-azidoethoxymethyl- and 2-azidoethoxyethylphosphonates was elaborated. The application of microwave irradiation shortened the reaction time to 10 min in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd4c6fb1da823f56dd968e9f1f68fb5
https://doi.org/10.1002/ardp.201200421
https://doi.org/10.1002/ardp.201200421