Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Andrzej Czyrski"'
Autor:
Konrad Lewandowski, Agnieszka Karbownik, Andrzej Czyrski, Hanna Urjasz, Joanna Stanisławiak-Rudowicz, Edmund Grześkowiak, Edyta Szałek
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 81, Iss 2, Pp 263-278 (2024)
Olaparib, an oral poly-ADP ribose polymerase (PARP) inhibitor, is a relatively new anticancer drug. It is essential to find TDM-guided dosage for better safety and tolerability of patients. However, first, it is important to develop a suitable analyt
Externí odkaz:
https://doaj.org/article/d88f74306b6e406baae09e6342e10085
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1774 (2023)
This study aimed to analyze the factors that impact the cloud point extraction of ciprofloxacin, levofloxacin, and moxifloxacin. The following independent variables were analyzed: Triton X-114 concentration, NaCl concentration, pH, and incubation tem
Externí odkaz:
https://doaj.org/article/04e3c91a89d5437a829fe8088de89c0e
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1961 (2021)
Second generation triazoles are widely used as first-line drugs for the treatment of invasive fungal infections, including aspergillosis and candidiasis. This class, along with itraconazole, voriconazole, posaconazole, and isavuconazole, is character
Externí odkaz:
https://doaj.org/article/8c6f41a950264a1995cf13296a6765fa
Publikováno v:
Pharmaceutics, Vol 13, Iss 12, p 1991 (2021)
The review includes studies dated 2011–2021 presenting the newest information on voriconazole (VCZ), mycophenolic acid (MPA), and vancomycin (VAN) therapeutic drug monitoring (TDM) in children. The need of TDM in pediatric patients has been emphasi
Externí odkaz:
https://doaj.org/article/d49593d467964f1a88909f96ce022060
Autor:
Andrzej Czyrski
Publikováno v:
Journal of Chemistry, Vol 2019 (2019)
The lipophilicity is an important parameter that influences the activity of the drugs in the human body. The reversed phase high performance thin layer chromatography was applied to determine the Log P values of ibuprofen, ketoprofen, naproxen, and f
Externí odkaz:
https://doaj.org/article/a7d407020e654098ae680dbdeb22d029
Autor:
Agnieszka Karbownik, Danuta Szkutnik-Fiedler, Andrzej Czyrski, Natalia Kostewicz, Paulina Kaczmarska, Małgorzata Bekier, Joanna Stanisławiak-Rudowicz, Marta Karaźniewicz-Łada, Anna Wolc, Franciszek Główka, Edmund Grześkowiak, Edyta Szałek
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 600 (2020)
The tyrosine kinase inhibitor sorafenib is the first-line treatment for patients with hepatocellular carcinoma (HCC), in which hyperlipidemia and type 2 diabetes mellitus (T2DM) may often coexist. Protein transporters like organic cation (OCT) and mu
Externí odkaz:
https://doaj.org/article/d7cbe8cda674484da883f39507102113
Autor:
Andrzej Czyrski, Bartłomiej Kupczyk
Publikováno v:
Journal of Chemistry, Vol 2013 (2013)
Mercaptopurine and its derivatives are used in the treatment of leukemia. To estimate their lipophilicity, a simple and novel thin layer chromatography method was developed. The mobile phase was the mixture of acetonitrile and water. The acetonitrile
Externí odkaz:
https://doaj.org/article/c5bac4ca0c9e4520a90b4c3c0619b304
Publikováno v:
New Journal of Chemistry. 44:7484-7489
Lipophilicity plays a significant role as a determinant of biological properties. Reversed-phase high-performance thin layer chromatography (HP-TLC) was applied to determine the log P values of chelidonine, allocryptopine, sanguinarine chloride and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10342979f65878efbae1456c14a7881b
https://doi.org/10.1039/d0nj00307g
https://doi.org/10.1039/d0nj00307g
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1961, p 1961 (2021)
Pharmaceutics, Vol 13, Iss 1961, p 1961 (2021)
Second generation triazoles are widely used as first-line drugs for the treatment of invasive fungal infections, including aspergillosis and candidiasis. This class, along with itraconazole, voriconazole, posaconazole, and isavuconazole, is character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bb98c60fd6391bacd2db78775cb1d0
https://pubmed.ncbi.nlm.nih.gov/34834376
https://pubmed.ncbi.nlm.nih.gov/34834376
Autor:
Hubert Jarzębski, Andrzej Czyrski
Publikováno v:
Processes; Volume 8; Issue 4; Pages: 473
Processes, Vol 8, Iss 473, p 473 (2020)
Processes, Vol 8, Iss 473, p 473 (2020)
The aim of this study was to find the best design that is suitable for optimizing the recovery of the representatives of the 2nd, 3rd and 4th generation of fluoroquinolones. The following designs were applied: Central Composite Design, Box–Behnken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80725d3220421e0fcadea345fe91516