Zobrazeno 1 - 10 of 197 pro vyhledávání: '"Andrzej, Wojcik"'
1
Akademický článek
Chromosomal damage, gene expression and alternative transcription in human lymphocytes exposed to mixed ionizing radiation as encountered in space
Autor: Milagrosa López Riego, Prabodha Kumar Meher, Beata Brzozowska, Pamela Akuwudike, Martin Bucher, Ursula Oestreicher, Lovisa Lundholm, Andrzej Wojcik
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Astronauts travelling in space will be exposed to mixed beams of particle radiation and photons. Exposure limits that correspond to defined cancer risk are calculated by multiplying absorbed doses by a radiation-type specific quality factor
Externí odkaz: https://doaj.org/article/328759b664b64b5b8a856944e573e791
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2
Akademický článek
Impact of fractionated cisplatin and radiation treatment on cell growth and accumulation of DNA damage in two normal cell types differing in origin
Autor: Pamela Akuwudike, Milagrosa López-Riego, Cloé Dehours, Lovisa Lundholm, Andrzej Wojcik
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Evidence on the impact of chemotherapy on radiotherapy-induced second malignant neoplasms is controversial. We estimated how cisplatin modulates the in vitro response of two normal cell types to fractionated radiation. AHH-1 lymphoblasts and
Externí odkaz: https://doaj.org/article/2fe9f108a6f14ae4a1aa76ded4416ccd
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3
Akademický článek
Short- and long-term effects of radiation exposure at low dose and low dose rate in normal human VH10 fibroblasts
Autor: Pamela Akuwudike, Milagrosa López-Riego, Michal Marczyk, Zuzana Kocibalova, Fabian Brückner, Joanna Polańska, Andrzej Wojcik, Lovisa Lundholm
Publikováno v: Frontiers in Public Health, Vol 11 (2023)
IntroductionExperimental studies complement epidemiological data on the biological effects of low doses and dose rates of ionizing radiation and help in determining the dose and dose rate effectiveness factor.MethodsHuman VH10 skin fibroblasts expose
Externí odkaz: https://doaj.org/article/5c86d6fb083a4b67b44523363d10d464
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4
Akademický článek
Hypothermia differentially modulates the formation and decay of NBS1, γH2AX and 53BP1 foci in U2OS cells exposed to gamma radiation
Autor: Magdalena Płódowska, Wiktoria Krakowiak, Aneta Węgierek-Ciuk, Anna Lankoff, Karol Szary, Krzysztof Lis, Andrzej Wojcik, Halina Lisowska
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract In studies on the mechanism of DNA damage response where ionizing radiation is used as the DNA damaging agent, cells are often exposed to ionizing radiation on melting ice (corresponding to 0.8 °C). The purpose of this procedure is to inhib
Externí odkaz: https://doaj.org/article/9c85d2c893b24898a944cf125f51fb09
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5
Akademický článek
The order of sequential exposure of U2OS cells to gamma and alpha radiation influences the formation and decay dynamics of NBS1 foci.
Autor: Adrianna Tartas, Lovisa Lundholm, Harry Scherthan, Andrzej Wojcik, Beata Brzozowska
Publikováno v: PLoS ONE, Vol 18, Iss 6, p e0286902 (2023)
DNA double strand breaks (DSBs) are a deleterious form of DNA damage. Densely ionising alpha radiation predominantly induces complex DSBs and sparsely ionising gamma radiation-simple DSBs. We have shown that alphas and gammas, when applied simultaneo
Externí odkaz: https://doaj.org/article/dff72023ead6420fa5d91ab638f7fca5
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8
Akademický článek
Monte Carlo Modeling of DNA Lesions and Chromosomal Aberrations Induced by Mixed Beams of Alpha Particles and X-Rays
Autor: Beata Brzozowska, Adrianna Tartas, Andrzej Wojcik
Publikováno v: Frontiers in Physics, Vol 8 (2020)
Prediction of health risks associated with exposure to mixed beams of high- and low-linear energy transfer ionizing radiation is based on the assumption that the biological effect caused by mixed radiation equals the sum of effects resulting from the
Externí odkaz: https://doaj.org/article/59166ed641ce4f7f90cf28a3d2ba9ed3
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9
Akademický článek
Cisplatin Reduces the Frequencies of Radiotherapy-Induced Micronuclei in Peripheral Blood Lymphocytes of Patients with Gynaecological Cancer: Possible Implications for the Risk of Second Malignant Neoplasms
Autor: Aneta Węgierek-Ciuk, Anna Lankoff, Halina Lisowska, Piotr Kędzierawski, Pamela Akuwudike, Lovisa Lundholm, Andrzej Wojcik
Publikováno v: Cells, Vol 10, Iss 10, p 2709 (2021)
Gynaecologic cancers are common among women and treatment includes surgery, radiotherapy or chemotherapy, where the last two methods induce DNA damage in non-targeted cells like peripheral blood lymphocytes (PBL). Damaged normal cells can transform l
Externí odkaz: https://doaj.org/article/f2d8740c4430432d8ba522c714f74062
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10
The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo
Autor: Milagrosa López-Riego, Magdalena Płódowska, Milena Lis-Zajęcka, Kamila Jeziorska, Sylwia Tetela, Aneta Węgierek-Ciuk, Daniel Sobota, Janusz Braziewicz, Lovisa Lundholm, Halina Lisowska, Andrzej Wojcik
Candidate ionising radiation exposure biomarkers must be validated in humans exposed in vivo. Blood from patients undergoing positron emission tomography - computed tomography scan (PET-CT) and skeletal scintigraphy (scintigraphy) was drawn before (0
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93a2a24ab0bbc3f3d76d417f18b30c6f
https://doi.org/10.21203/rs.3.rs-2873007/v1
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