Running performance at high running velocities is impaired but V'O(₂max) and peripheral endothelial function are preserved in IL-6⁻/⁻ mice.

Autor: Marta Wojewoda, Katarzyna Kmiecik, Renée Ventura-Clapier, Dominique Fortin, Marta Onopiuk, Justyna Jakubczyk, Barbara Sitek, Andrzej Fedorowicz, Joanna Majerczak, Karol Kaminski, Stefan Chlopicki, Jerzy Andrzej Zoladz

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e88333 (2014)

It has been reported that IL-6 knockout mice (IL-6⁻/⁻) possess lower endurance capacity than wild type mice (WT), however the underlying mechanism is poorly understood. The aim of the present work was to examine whether reduced endurance running

Externí odkaz: https://doaj.org/article/dcecd614a8f74e1eb7c5d6d1aab65f7d

Comparison of Pulmonary and Systemic NO- and PGI

Autor: Andrzej, Fedorowicz, Elżbieta, Buczek, Łukasz, Mateuszuk, Elzbieta, Czarnowska, Barbara, Sitek, Agnieszka, Jasztal, Antonina, Chmura-Skirlińska, Mobin, Dib, Sebastian, Steven, Andreas, Daiber, Stefan, Chlopicki

Publikováno v: Oxidative Medicine and Cellular Longevity

Diabetes increases the risk of pulmonary hypertension and is associated with alterations in pulmonary vascular function. Still, it is not clear whether alterations in the phenotype of pulmonary endothelium induced by diabetes are distinct, as compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df90da0bdb0a1469796de630469037f3
https://pubmed.ncbi.nlm.nih.gov/29967661

Alterations in NO- and PGI_{2}- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer : relationship with pulmonary endothelial dysfunction and systemic inflammation

Autor: Lukasz Mateuszuk, R. Gurbiel, Joanna Wietrzyk, Elzbieta Buczek, Stefan Chlopicki, Agnieszka Jasztal, Andrzej Fedorowicz, Tomasz Wojcik, Agnieszka Denslow, Barbara Sitek, A. Chmura Skirlinska, Bartosz Proniewski, Edyta Kus

Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
BMC Cancer

Background Patients with cancer develop endothelial dysfunction and subsequently display a higher risk of cardiovascular events. The aim of the present work was to examine changes in nitric oxide (NO)- and prostacyclin (PGI2)-dependent endothelial fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a95a39dd1415c737d8eea5a1f2b832
https://ruj.uj.edu.pl/xmlui/handle/item/73287

LSC Abstract – Lung-derived prostacyclin (PGI) in endothelial dysfunction in db/db mice

Autor: Agnieszka Jasztal, Maria Walczak, Andreas Daiber, Agnieszka Zakrzewska, Sebastian Steven, Antonina Chmura-Skirlinska, Tomasz Skórka, Andrzej Fedorowicz, Stefan Chlopicki, Mobin Dip, Elzbieta Buczek

Publikováno v: ERS Lung Science Conference 2016.

Aim: Increased risk of pulmonary hypertension and not clear response of pulmonary endothelium to diabetes were reasons to compare nitric oxide (NO) and PGI-dependent function in pulmonary and systemic circulation in diabetes type II. Methods: In fast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6555a9c6de8dcfc07673ba3cd537f5f8
https://doi.org/10.1183/13993003.congress-2016.pp128

Antithrombotic properties of water-soluble carbon monoxide-releasing molecules.: Anti-thrombotic properties of CO-RMs

Autor: Elżbieta Grochal, Tomasz Brzoska, Brian E. Mann, Tetsumei Urano, Wlodzimierz Buczko, Andrzej Mogielnicki, Andrzej Fedorowicz, Agnieszka Leszczynska, Roberto Motterlini, Karol Kramkowski, Stefan Chlopicki

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2012, 32 (9), pp.2149-57. ⟨10.1161/ATVBAHA.112.253989⟩

Objective— We compared the antithrombotic effects in vivo of 2 chemically different carbon monoxide–releasing molecules (CORM-A1 and CORM-3) on arterial and venous thrombus formation and on hemostatic parameters such as platelet activation, coagu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ab5bfd89e78f0c9a1d845ca066094d
https://doi.org/10.1161/atvbaha.112.253989