Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

Autor: Linder, Simon, Hoogstraat, Marlous, Stelloo, Suzan, Eickhoff, Nils, Schuurman, Karianne, de Barros, Hilda, Alkemade, Maartje, Bekers, Elise M., Severson, Tesa M., Sanders, Joyce, Huang, Chia Chi Flora, Morova, Tunc, Altintas, Umut Berkay, Hoekman, Liesbeth, Kim, Yongsoo, Baca, Sylvan C., Sjöström, Martin, Zaalberg, Anniek, Hintzen, Dorine C., de Jong, Jeroen, Kluin, Roelof J.C., de Rink, Iris, Giambartolomei, Claudia, Seo, Ji Heui, Pasaniuc, Bogdan, Altelaar, Maarten, Medema, René H., Feng, Felix Y., Zoubeidi, Amina, Freedman, Matthew L., Wessels, Lodewyk F.A., Butler, Lisa M., Lack, Nathan A., van der Poel, Henk, Bergman, Andries M., Zwart, Wilbert, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

Publikováno v: Cancer Discovery, 12(9), 2074-2097. American Association for Cancer Research Inc.
Cancer Discovery, 12(9), 2074. American Association for Cancer Research Inc.
Linder, S, Hoogstraat, M, Stelloo, S, Eickhoff, N, Schuurman, K, de Barros, H, Alkemade, M, Bekers, E M, Severson, T M, Sanders, J, Huang, C-C F, Morova, T, Altintas, U B, Hoekman, L, Kim, Y, Baca, S C, Sjöström, M, Zaalberg, A, Hintzen, D C, de Jong, J, Kluin, R J C, de Rink, I, Giambartolomei, C, Seo, J-H, Pasaniuc, B, Altelaar, M, Medema, R H, Feng, F Y, Zoubeidi, A, Freedman, M L, Wessels, L F A, Butler, L M, Lack, N A, van der Poel, H, Bergman, A M & Zwart, W 2022, ' Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence ', Cancer discovery, vol. 12, no. 9, pp. 2074-2097 . https://doi.org/10.1158/2159-8290.CD-21-0576
Cancer Discov
Cancer discovery, 12(9)
Cancer discovery, vol 12, iss 9
Cancer discovery, 12(9), 2074-2097. American Association for Cancer Research Inc.

In prostate cancer, androgen receptor (AR)–targeting agents are very effective in various disease stages. However, therapy resistance inevitably occurs, and little is known about how tumor cells adapt to bypass AR suppression. Here, we performed in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039c32e9b5e18899785f8d02a47ca186
https://doi.org/10.1158/2159-8290.cd-21-0576

Does prolactin induce apoptosis? Evidences in a prostate cancer in vitro model

Autor: Aldo E. Calogero, Maria Chiara Giuffrida, Anna Perdichizzi, Enzo Vicari, Rosario D'Agata, S. La Vignera, D. Giuffrida

Publikováno v: Journal of endocrinological investigation. 33(5)

Background: Prolactin (PRL) regulates prostate growth and differentiation. Some studies have suggested that PRL has a pro-apoptotic effect on a myeloma cell line and in newt spermatogonia. The proliferative effect of PRL on prostate cancer cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166f96f0e17e336256032af26d759cee
https://pubmed.ncbi.nlm.nih.gov/20009491

G protein-associated, specific membrane binding sites mediate the neuroprotective effect of dehydroepiandrosterone

Autor: Iakovos Lazaridis, Ioannis Charalampopoulos, Christos Tsatsanis, Achille Gravanis, Vassilia-Ismini Alexaki, Erene Dermitzaki, Theodora Calogeropoulou, Nicolaos Avlonitis, Andrew N. Margioris, Elias Castanas

Publikováno v: FASEB Journal 20:1(Jan2006):577

The neurosteroid dehydroepiandrosterone (DHEA) at 1 nM protects NMDA-/GABAA-receptor negative neural crest-derived PC12 cells from apoptosis. We now report that membrane-impermeable DHEA-BSA conjugate replaces unconjugated DHEA in protecting serum-de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cc2d23207582c7d9bb7e9e09dd4fd7
http://olympias.lib.uoi.gr/jspui/handle/123456789/21468

Studies on male adnexual fluids. 2 : Experimental studies on dog prostatic fluid (Effects of pituitary, adrenal and other hormones)

Autor: TANABE, Yasutami

Publikováno v: 泌尿器科紀要. 11(6):478-492

Effects of pituitary, adrenal, anabolic, thyroid and anti t hyroid hormones on amount of fluid secreted and contents of protein and fructose in the prostatic fluid obtained transurethrally on the Huggins'dog were investigated. As a rule, the hormones

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::1a7fe06a9309b5c797ae5b72e129dc35
http://hdl.handle.net/2433/112765

Studies on male adnexal fluids. 1 : Experimental studies on dog prostatic fluid (Normal dogs and effect of sexual hormones)

Autor: TANABE, Yasutami

Publikováno v: 泌尿器科紀要. 11(6):466-477

Prostatic function is most accurately represented by it s fluid. Using dogs as experimental animal, prostatic fluid was collected trans-urethrally by the Huggins' method, and the amount of fluid secreted, protein content and fructose level were measu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::630898db9c51993eb9b67fd85ec70ef9
http://hdl.handle.net/2433/112766