Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Andriy M, Babsky"'
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Cardiovascular complications are the major cause of mortality and morbidity in diabetic patients. The changes in myocardial structure and function associated with diabetes are collectively called diabetic cardiomyopathy. Numerous molecular mechanisms
Externí odkaz:
https://doaj.org/article/1a8a9fca245846c6b391fcbe74324ce6
Autor:
N. S. Finiuk, Ya. R. Shalai, S. M. Mandzynets, V. P. Hreniukh, M. V. Popovych, Andriy M. Babsky
Publikováno v:
Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 61-67 (2021)
Thiazole derivatives were shown to have toxic effects in vitro on cancer cells of different origin and can be considered as potentially antineoplastic, but their effect on the normal tissues needs to be studied. In this research the newly synthesized
Autor:
Nataliya Mitina, V. P. Hreniukh, O. R. Kulachkovskyy, S. M. Mandzynets, Ya. R. Shalai, O. S. Zaichenko, M. V. Popovych, Andriy M. Babsky
Publikováno v:
Біологічні студії, Vol 15, Iss 2, Pp 15-24 (2021)
Background. A pronounced cytotoxic action of the thiazole derivatives complexed with polymeric carriers on tumor cells in vitro was reported earlier, while no cytotoxicity of these compounds was detected toward noncancerous cells. It was found that t
Autor:
Nataliya Mitina, O. S. Zaichenko, Mykola D. Obushak, Yu. V. Ostapiuk, O. Yu. Klyuchivska, Andriy M. Babsky, Rostyslav Stoika, I. I. Ivasechko, N. S. Finiuk
Publikováno v:
Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 39-51 (2021)
Thiazole derivatives are perspective antitumor compounds characterized by a broad range of bioactivity, while polymeric carriers are widely used to enhance the efficiency of biological action of drugs, improve their biocompatibility and water solubil
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 7, Pp 658-666 (2005)
Effects of an alkylating anticancer drug, cyclophosphamide (Cp), on 23Na signal intensity (23Na SI) and water apparent diffusion coefficient (ADC) were examined in subcutaneously - implanted radiation-induced fibrosarcoma (RIF-1) tumors by in vivo23N
Externí odkaz:
https://doaj.org/article/d560fac0d42c4b1d95cbb2d6ad061dda
Autor:
Ya. R. Shalai, O. R. Kulachkovskyy, N. S. Finiuk, M. V. Popovych, Andriy M. Babsky, S. M. Mandzynets, V. P. Hreniukh
Publikováno v:
Біологічні студії, Vol 13, Iss 1, Pp 51-60 (2019)
The influence of newly synthesized thiazole derivative N-(5-benzyl-1,3-thiazol-2-yl)-3,5-dimethyl-1-benzofuran-2-carboxamide on cellular ultrastructure and antioxidant system activity in lymphoma cells was studied in vitro. A pronounced cytotoxic a
Autor:
Andriy M. Babsky, Kristine Salmina, Jekabs Krigerts, Bogdan I. Gerashchenko, Jekaterina Erenpreisa
Publikováno v:
Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology. 24:220-234
Rat liver stem-like epithelial cells (WB-F344) that under certain conditions may differentiate into hepa- tocyte and biliary lineages were subjected to acute X-irradiation with the aim to examine cell cycle peculiarities dur- ing the course of surviv
Autor:
Andriy M. Babsky, Yu. V. Ostapiuk, Rostyslav Stoika, Mykola D. Obushak, V. P. Hreniukh, Vasyl S. Matiychuk, N. S. Finiuk
Publikováno v:
Біологічні студії, Vol 12, Iss 2, Pp 25-34 (2018)
We have found that new derivatives of 2-amino-5-benzylthiazole possess cytotoxic action towards human tumor cells (Finiuk et al., Biopolym. Cell, 2017; Finiuk et al., Ukr. Biochem. J., 2018). A release of the chemotherapeutic drugs into the environme
Publikováno v:
Experimental and Clinical Physiology and Biochemistry. 2018:38-42
Publikováno v:
Біологічні студії, Vol 12, Iss 2, Pp 35-44 (2018)
One of the main problems of chemotherapy is development of negative side effects, when anti-tumor drugs damage healthy cells, in particular hepatocytes. Liver is the main detoxifying organ in human and animals. This organ plays an important role in t