Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Andrius Kazlauskas"'
Autor:
Daniel E. Maidana, Lucia Gonzalez-Buendia, Sara Pastor-Puente, Afsar Naqvi, Eleftherios Paschalis, Andrius Kazlauskas, Joan W. Miller, Demetrios G. Vavvas
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-8 (2023)
Abstract Photoreceptor cell death and immune cell infiltration are two major events that contribute to retinal degeneration. However, the relationship between these two events has not been well delineated, primarily because of an inadequate understan
Externí odkaz:
https://doaj.org/article/c9daf56370424ae0909cfac31580e9de
Autor:
Yajian Duan, Wenyi Wu, Jing Cui, Joanne Aiko Matsubara, Andrius Kazlauskas, Gaoen Ma, Xiaorong Li, Hetian Lei
Publikováno v:
BMC Ophthalmology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Epiretinal membranes in patients with proliferative vitreoretinopathy (PVR) consist of extracellular matrix and a number of cell types including retinal pigment epithelial (RPE) cells and fibroblasts, whose contraction causes reti
Externí odkaz:
https://doaj.org/article/57d4d7414a144c54ae9ff57857f0c767
Autor:
Samuel Cubillos, Andrius Kazlauskas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1610 (2024)
Diabetic retinopathy (DR) is the most common complication that develops in patients with diabetes mellitus (DM) and is the leading cause of blindness worldwide. Fortunately, sight-threatening forms of DR develop only after several decades of DM. This
Externí odkaz:
https://doaj.org/article/822b918ac04946b0b827cc27d17ce1de
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2431 (2023)
The therapeutic benefit provided by anti-vascular endothelial growth factor (VEGF) for patients with vision-threatening conditions such as diabetic retinopathy (DR) demonstrates the important role of VEGF in this affliction. Cytokines, which can be e
Externí odkaz:
https://doaj.org/article/1b352bb3117a420dbe4d05a1278843c3
Autor:
Yanliang Li, Basma Baccouche, Norma Del-Risco, Jason Park, Amy Song, J. Jason McAnany, Andrius Kazlauskas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10869 (2023)
The purpose of this study was to investigate the reason that diabetic retinopathy (DR) is delayed from the onset of diabetes (DM) in diabetic mice. To this end, we tested the hypothesis that the deleterious effects of DM are initially tolerated becau
Externí odkaz:
https://doaj.org/article/b0a879ecd99241869fafd71888955e7b
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8698 (2023)
The clinical success of neutralizing vascular endothelial growth factor (VEGF) has unequivocally identified VEGF as a driver of retinal edema that underlies a variety of blinding conditions. VEGF is not the only input that is received and integrated
Externí odkaz:
https://doaj.org/article/9d36ec6dc8ce4bf8aa99298ff4f2843e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6402 (2023)
The purpose of this study was to identify genes that mediate VEGF-induced permeability. We performed RNA-Seq analysis on primary human retinal endothelial cells (HRECs) cultured in normal (5 mM) and high glucose (30 mM) conditions that were treated w
Externí odkaz:
https://doaj.org/article/c8ad0a61e7584a85a8fffe84fbaa595d
Autor:
Faisal Masood, Rohan Bhattaram, Mark I. Rosenblatt, Andrius Kazlauskas, Jin-Hong Chang, Dimitri T. Azar
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Aberrant lymphatic system function has been increasingly implicated in pathologies such as lymphedema, organ transplant rejection, cardiovascular disease, obesity, and neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disea
Externí odkaz:
https://doaj.org/article/d074ad6a3e7f4e52923a4c8999e55772
Autor:
Haote Han, Yanhui Yang, Zhuo Han, Luping Wang, Lijun Dong, Hui Qi, Bing Liu, Jingkui Tian, Bart Vanhaesebroeck, Andrius Kazlauskas, Guoming Zhang, Shaochong Zhang, Hetian Lei
Publikováno v:
Cells, Vol 12, Iss 2, p 207 (2023)
Epithelial mesenchymal transition (EMT) plays a vital role in a variety of human diseases including proliferative vitreoretinopathy (PVR), in which retinal pigment epithelial (RPE) cells play a key part. Transcriptomic analysis showed that the phosph
Externí odkaz:
https://doaj.org/article/7d119c48b5544e43876fdb3429fbeb2e
Autor:
Egle Strainiene, Mindaugas Binkis, Silvija Urnikyte, Vaidotas Stankevicius, Ausra Sasnauskiene, Gabrielis Kundrotas, Andrius Kazlauskas, Kestutis Suziedelis
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Since the first evidence suggesting existence of stem-like cancer cells, the process of cells reprogramming to the stem cell state remains as an attractive tool for cancer stemness research. Current knowledge in the field of cance
Externí odkaz:
https://doaj.org/article/37d4c7cfa2604657a489634718deb92f