Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Andris Kaminskis"'
Autor:
Brian G. Schuster, Kenneth C. Lasseter, Andris Kaminskis, Mark T. Marino, Emil T. Lin, Ralf P. Brueckner
Publikováno v:
The Journal of Clinical Pharmacology. 38:227-235
This study was conducted to determine the pharmacokinetics and pharmacodynamics of pyridostigmine given as 30 mg of pyridostigmine bromide every 8 hours in healthy subjects. Plasma pyridostigmine concentration and red blood cell acetylcholinesterase
Autor:
J. von Bredow, Nelson L. Adams, Andris Kaminskis, John V. Wade, Kevin D. Corcoran, G. Maitland
Publikováno v:
Fundamental and Applied Toxicology. 17:782-789
Pretreatment of nonhuman primates with physostigmine (Phy) and scopolamine or physostigmine and trihexyphenidyl 25 min before exposure to 2 LD50 soman im resulted in complete survival without convulsions or loss of consciousness. When identically pre
Autor:
Andris Kaminskis, Theresa M. Tezak-Reid, John V. Wade, James R. Stewart, Kevin D. Corcoran, Fred W. Stemler, Isaac J. Hayward, Ming L. Shih, Michael P. Mccluskey
Publikováno v:
Fundamental and Applied Toxicology. 16:548-558
The pharmacokinetics and cardiovascular pharmacodynamics of two oximes were studied in unanesthetized pigs. Effects of 2-[(hydroxyimino)methyl]-1-methylpyridinium chloride (pralidoxime chloride; 2-PAM Cl; 50 μmon/kg) were compared with those of 1,1-
Autor:
FRED W. STEMLER, THERESA M. TEZAK-REID, MICHAEL P. MCCLUSKEY, ANDRIS KAMINSKIS, KEVIN D. CORCORAN, MING L. SHIH, JAMES R. STEWART, JOHN V. WADE, ISAAC J. HAYWARD
Publikováno v:
Toxicological Sciences. 16:548-558
Autor:
James J. Jaeger, John H. Parrish, Theresa M. Tezak-Reid, Holcombe H. Hurt, Kevin D. Corcoran, Fred W. Stemler, Andris Kaminskis
Publikováno v:
Fundamental and Applied Toxicology. 14:96-103
Physostigmine, as a pretreatment candidate for nerve agent poisoning, was examined for cardiopulmonary side effects. Cardiovascular and pulmonary parameters were monitored in unanesthetized domestic pigs which received pulmonary arterial infusion of
Autor:
Andris Kaminskis, Craig A. Calamaio, Dale G. Martin, Larrel W. Harris, Claude L. Woodard, Dana R. Anderson
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 23(3)
Erythrocyte and Plasma Cholinesterase Activity in Male and Female Rhesus Monkeys before and after Exposure to Sarin. Woodard, C. L., Calamaio, C. A., Kaminskis, A., Anderson, D. R., Harris, L. W., and Martin, D. G. (1994). Fundam. Appl Toxicol. 23, 3
Autor:
James R. Stewart, Irwin Koplovitz, Andris Kaminskis, Vincent C. Gresham, Leland W. Dochterman
Publikováno v:
Archives of toxicology. 66(9)
Cyclohexylmethylphosphonofluoridate (CMPF) is an organophosphate cholinesterase inhibitor with military significance. The purpose of these studies was 1) to determine the acute toxicity of CMPF in the male rhesus monkey, 2) to evaluate the efficacy o
Publikováno v:
Toxicology and Applied Pharmacology. 88:66-76
The in vivo time course of cholinesterase inhibition was measured in brain, lung, spleen, hind limb skeletal muscle, diaphragm, intestine, kidney, heart, liver, and plasma of rats receiving 90 μg/kg soman, im. This dose of soman produced severe resp
Publikováno v:
Clinical Chemistry. 20:1116-1120
We describe a sensitive, accurate automated method for the simultaneous measurement of methemoglobin and total hemoglobin in blood. The method can be used for either continuous in vivo monitoring or intermittent sampling at a rate of 20/h. Standardiz
Publikováno v:
Fundamental and Applied Toxicology. 13:568-575
The dose-response (0.1 to 1000 mg/kg sc) effects of 2-( o -cresyl)-4H-1:3:2-benzodioxaphosphorin-2-oxide (CBDP; a metabolite of the organophosphorus compound tri- o -cresylphosphate) on total cholinesterase (ChE) and carboxylesterase (CaE) activities