Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Andris Abramenkovs"'
Ra-223 induces clustered DNA damage and inhibits cell survival in several prostate cancer cell lines
Publikováno v:
Translational Oncology, Vol 26, Iss , Pp 101543- (2022)
The bone-seeking radiopharmaceutical Xofigo (Radium-223 dichloride) has demonstrated both extended survival and palliative effects in treatment of bone metastases in prostate cancer. The alpha-particle emitter Ra-223, targets regions undergoing activ
Externí odkaz:
https://doaj.org/article/f231e47f8e6a4aec88850ffac74aa27d
Autor:
Andris Abramenkovs, Bo Stenerlöw
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209594 (2018)
DNA double-strand breaks (DSBs) are the most deleterious lesions that can arise in cells after ionizing radiation or radiometric drug treatment. In addition to prompt DSBs, DSBs may also be produced during repair, evolving from a clustered DNA damage
Externí odkaz:
https://doaj.org/article/37f5f8169ade433c9de94034bb194cb3
Autor:
Sara Lundsten, Anja C. Mortensen, Marika Nestor, Bo Stenerlöw, Andris Abramenkovs, Diana Spiegelberg
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Oncogenic client-proteins of the chaperone Heat shock protein 90 (HSP90) insure unlimited tumor growth and are involved in resistance to chemo- and radiotherapy. The HSP90 inhibitor Onalespib initiates the degradation of oncoproteins, and might also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e1b8a239730db93ba165772ced511d
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422436
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422436
Autor:
Andris, Abramenkovs, Bo, Stenerlöw
Publikováno v:
Radiation research. 188(6)
Uncontrolled generation of DNA double-strand breaks (DSBs) in cells is regarded as a highly toxic event that threatens cell survival. Radiation-induced DNA DSBs are commonly measured by pulsed-field gel electrophoresis, microscopic evaluation of accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07e803b043dc04fcce52e7eb61ff56b3
https://pubmed.ncbi.nlm.nih.gov/28952912
https://pubmed.ncbi.nlm.nih.gov/28952912
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 769:1-10
Efficient and correct repair of DNA double-strand break (DSB) is critical for cell survival. Defects in the DNA repair may lead to cell death, genomic instability and development of cancer. The catalytic subunit of DNA-dependent protein kinase (DNA-P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b347ba47c06030c0f60a98074343e600
https://doi.org/10.1016/j.mrfmmm.2014.06.004
https://doi.org/10.1016/j.mrfmmm.2014.06.004
Autor:
Andris Abramenkovs
Publikováno v:
Nuclear Technology and Radiation Protection, Vol 26, Iss 1, Pp 78-83 (2011)
In May 1995, the Latvian government decided to shut down the Salaspils Research Reactor and to dispense with nuclear energy in the future. The reactor has been out of operation since July 1998. A conceptual study on the decommissioning of the Salaspi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a563ec109a9235188a850d61b56ea23
http://www.doiserbia.nb.rs/img/doi/1451-3994/2011/1451-39941101078A.pdf
http://www.doiserbia.nb.rs/img/doi/1451-3994/2011/1451-39941101078A.pdf
Autor:
Marika Nestor, Andris Abramenkovs, Anja C. Mortensen, Bo Stenerlöw, Adrian Dascalu, Gamze Kuku, Diana Spiegelberg
Publikováno v:
Oncotarget
// Diana Spiegelberg 1 , Adrian Dascalu 1 , Anja C. Mortensen 1 , Andris Abramenkovs 1 , Gamze Kuku 1 , Marika Nestor 1, 2 , Bo Stenerlow 1 1 Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden 2 Unit of Otolaryngolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18aae31ad6a2a1eace30c854aeaa9727
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-247054
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-247054