Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Andrii Bazylevich"'
Autor:
Olga Semenova, Dmytro Kobzev, Iryna Hovor, Melad Atrash, Faina Nakonechny, Olesia Kulyk, Andrii Bazylevich, Gary Gellerman, Leonid Patsenker
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 247 (2023)
Antibiotic resistance of pathogenic bacteria dictates the development of novel treatment modalities such as antimicrobial photodynamic therapy (APDT) utilizing organic dyes termed photosensitizers that exhibit a high cytotoxicity upon light irradiati
Externí odkaz:
https://doaj.org/article/4d5f54b02e02412fa923ef02446ea018
Autor:
Olga Furman, Alisa Zaporozhets, Dror Tobi, Andrii Bazylevich, Michael A. Firer, Leonid Patsenker, Gary Gellerman, Bat Chen R. Lubin
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1505 (2022)
The epidermal growth factor–epidermal growth factor receptor (EGF-EGFR) pathway has become the main focus of selective chemotherapeutic intervention. As a result, two classes of EGFR inhibitors have been clinically approved, namely monoclonal antib
Externí odkaz:
https://doaj.org/article/da8b9694f98443a2b2b3462694e6d015
Autor:
Kalishwaralal Kalimuthu, Bat-Chen Lubin, Andrii Bazylevich, Gary Gellerman, Ofer Shpilberg, Galia Luboshits, Michael A. Firer
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Peptide-drug-conjugates (PDCs) are being developed as an effective strategy to specifically deliver cytotoxic drugs to cancer cells. However one of the challenges to their successful application is the relatively low stability of
Externí odkaz:
https://doaj.org/article/769e9a94a2704d54834923808d687bc0
Autor:
Ebaston, Thankarajan, Helena, Tuchinsky, Sarit, Aviel-Ronen, Andrii, Bazylevich, Gary, Gellerman, Leonid, Patsenker
Publikováno v:
Journal of Controlled Release. 343:506-517
Photodynamic therapy (PDT) utilizing an organic dye (photosensitizer) capable of killing cancer cells in the body upon light irradiation is one of the promising non-invasive treatment modalities for many cancers. A known drawback of PDT is a side-eff
Autor:
Dmytro Kobzev, Chandrashekhar Prasad, Dipak Walunj, Hodaya Gotman, Olga Semenova, Andrii Bazylevich, Leonid Patsenker, Gary Gellerman
Publikováno v:
European Journal of Medicinal Chemistry. 252:115298
Autor:
Dmytro Kobzev, Olga Semenova, Anatoliy Tatarets, Andrii Bazylevich, Gary Gellerman, Leonid Patsenker
Publikováno v:
Dyes and Pigments. 212:111101
Publikováno v:
Dyes and Pigments. 211:111095
Highly efficient near-IR cyclohexene cyanine photosensitizers for antibacterial photodynamic therapy
Autor:
Arjun Veliyil Prakash, Fares Yazabak, Iryna Hovor, Faina Nakonechny, Olesia Kulyk, Olga Semenova, Andrii Bazylevich, Gary Gellerman, Leonid Patsenker
Publikováno v:
Dyes and Pigments. 211:111053
Autor:
Ebaston Thankarajan, Dipak Walunj, Andrii Bazylevich, Chandrashekhar Prasad, Arkadi Hesin, Leonid Patsenker, Gary Gellerman
Publikováno v:
Photodiagnosis and photodynamic therapy. 37
A facile synthesis, biological evaluation and photodynamic properties of novel activatable anticancer molecular hybrids (chimeras) Ch and I-Ch are described. The chimeras consist of DNA methylating methyl triazene moiety and fluorogenic xanthene-cyan
Autor:
Gary Gellerman, Ortal Dorfman, Leonid D. Patsenker, Hodaya Gutman, Vered Marks, Arkadi Hesin, Andrii Bazylevich, Chandrashekhar Prasad
Publikováno v:
ACS Med Chem Lett
[Image: see text] We developed a highly potent anticancer agent, dolastatinol, which is a methylene hydroxyl derivative of dolastatin 10. Dolastatinol is a synthetic analog of dolastatin 10, synthesized by a solid-phase peptide Fmoc chemistry protoco