Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Andrii, Domanskyi"'
Publikováno v:
Brain Research Bulletin, Vol 217, Iss , Pp 111089- (2024)
Here we assess whether neuropathic pain hypersensitivity is attenuated by spinal administration of the imidazoline I1-receptor agonist LNP599 and whether the attenuation involves co-activation of α2-adrenoceptors. Spared nerve injury (SNI) model of
Externí odkaz:
https://doaj.org/article/5eeed733dc224c3aa6fb4cbd9d8f1a14
Autor:
Riikka Lampinen, Irina Belaya, Liudmila Saveleva, Jeffrey R. Liddell, Dzhessi Rait, Mikko T. Huuskonen, Raisa Giniatullina, Annika Sorvari, Liisi Soppela, Nikita Mikhailov, Isabella Boccuni, Rashid Giniatullin, Marcela Cruz-Haces, Julia Konovalova, Marja Koskuvi, Andrii Domanskyi, Riikka H. Hämäläinen, Gundars Goldsteins, Jari Koistinaho, Tarja Malm, Sweelin Chew, Kirsi Rilla, Anthony R. White, Nicholas Marsh-Armstrong, Katja M. Kanninen
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105753- (2022)
Under physiological conditions in vivo astrocytes internalize and degrade neuronal mitochondria in a process called transmitophagy. Mitophagy is widely reported to be impaired in neurodegeneration but it is unknown whether and how transmitophagy is a
Externí odkaz:
https://doaj.org/article/90b3b33e12fd4d749b99c1ac7e4e3bbb
Autor:
Emma Juuri, Pauli Tikka, Andrii Domanskyi, Ian Corfe, Wataru Morita, Peter J. Mckinnon, Nela Jandova, Anamaria Balic
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Ptch receptors 1 and 2 mediate Hedgehog signaling pivotal for organ development and homeostasis. In contrast to embryonic lethal Ptch1−/− phenotype, Ptch2−/− mice display no effect on gross phenotype. In this brief report, we provide evidence
Externí odkaz:
https://doaj.org/article/b9b419be925b40a99242f290831e568d
Autor:
Dale W. Prebble, Safak Er, Mingming Xu, Irena Hlushchuk, Andrii Domanskyi, Mikko Airavaara, Merrick G. Ekins, George D. Mellick, Anthony R. Carroll
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100472- (2022)
The neuronal protein α-synuclein (α-syn) is one of the main constituents of intracellular amyloid aggregations found in the post-mortem brains of Parkinson’s disease (PD) patients. Recently, we screened the MeOH extracts obtained from 300 sub-tro
Externí odkaz:
https://doaj.org/article/ebdbe234d624481a967c223a4a7ebfda
Autor:
Dale W. Prebble, Tanja M. Voser, Safak Er, Irena Hlushchuk, Andrii Domanskyi, Mikko Airavaara, Merrick G. Ekins, George D. Mellick, Anthony R. Carroll
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100302- (2022)
During a high-throughput screen of 300 Australian marine invertebrate extracts, the extract of the marine sponge Clathria (Thalysias) cf. hesperia was identified with α-synuclein binding activity. The bioassay-guided purification of this extract res
Externí odkaz:
https://doaj.org/article/d9b1edf9ef4c4f8cb9d92ed987c40d02
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/22fe0d9a442849699206851678799cf9
Autor:
Piotr Chmielarz, Andrii Domanskyi
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 11, Pp 2219-2221 (2021)
Externí odkaz:
https://doaj.org/article/c34cf57c9c814c1da601eb1bc61c144b
Autor:
Irena Hlushchuk, Justyna Barut, Mikko Airavaara, Kelvin Luk, Andrii Domanskyi, Piotr Chmielarz
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 563 (2022)
There are several links between insulin resistance and neurodegenerative disorders such as Parkinson’s disease. However, the direct influence of insulin signaling on abnormal α-synuclein accumulation—a hallmark of Parkinson’s disease—remains
Externí odkaz:
https://doaj.org/article/fd6b88769d4a4cf0bb8b3658290fd8f1
Autor:
Andrii Domanskyi, Rosanna Parlato
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 504 (2022)
Oxidative stress is typically reported in neurodegenerative diseases [...]
Externí odkaz:
https://doaj.org/article/2f6e782762244b46b188595f3a2c43d4
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The cytoskeleton is one of the most mobile and complex cell structures. It is involved in cellular transport, cell division, cell shape formation and adaptation in response to extra- and intracellular stimuli, endo- and exocytosis, migration, and inv
Externí odkaz:
https://doaj.org/article/5c47712607fc4c028df2d1a6c5134cf2