Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Andries Blokzijl"'
Autor:
Andries Blokzijl, Lei E Chen, Sigrun M Gustafsdottir, Jimmy Vuu, Gustav Ullenhag, Olle Kämpe, Ulf Landegren, Masood Kamali-Moghaddam, Håkan Hedstrand
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154214 (2016)
The diagnosis of malignant melanoma currently relies on clinical inspection of the skin surface and on the histopathological status of the excised tumor. The serum marker S100B is used for prognostic estimates at later stages of the disease, but anal
Externí odkaz:
https://doaj.org/article/13f7560764054bacb3ac9597061989c9
Autor:
Rasel Al-Amin, Lars Johansson, Eldar Abdurakhmanov, Nils Landegren, Liza Löf, Linda Arngården, Andries Blokzijl, Richard Svensson, Maria Hammond, Peter Lönn, Johannes Haybaeck, Masood Kamali-Moghaddam, Annika Jensen, U Helena Danielson, Per Artursson, Thomas Lundbäck, Ulf Landegren
Publikováno v:
Nucleic acids research. 50(22)
Drugs are designed to bind their target proteins in physiologically relevant tissues and organs to modulate biological functions and elicit desirable clinical outcomes. Information about target engagement at cellular and subcellular resolution is the
Autor:
Anita Morén, Ola Söderberg, Saskia Helmsing, Thomas Schirrmann, Michael Hust, Andries Blokzijl, Stefan Dübel, Karin Grannas, Ellen Hertz, Agata Zieba, Lei Chen, Ulf Landegren, Aristidis Moustakas
Publikováno v:
Molecular & Cellular Proteomics. 15:1848-1856
The cellular heterogeneity seen in tumors, with subpopulations of cells capable of resisting different treatments, renders single-treatment regimens generally ineffective. Accordingly, there is a great need to increase the repertoire of drug treatmen
Autor:
Chuan Jin, Yiwen Jiang, Fredrik J. Swartling, Malin Tirfing, Magnus Essand, Voichita D. Marinescu, Sven Nelander, E-Jean Tan, Andries Blokzijl, Naga Prathyusha Maturi, Yuan Xie, Lene Uhrbom, Lei Chen, Anders Sundström
We have recently identified LGR5 as a marker of an immature, neural stem cell-like cell of origin for glioblastoma (GBM). Here we have further investigated the role of LGR5 in GBM. We have found that in a panel of 61 patient-derived GBM stem cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57300eec36e4c3f20084c53901accdfe
https://europepmc.org/articles/PMC5692820/
https://europepmc.org/articles/PMC5692820/
Autor:
Dan Sunnemark, Gabriel von Euler, Harald Lund, Christina Classon, Ulf Landegren, Gucci Jijuan Gu, Andries Blokzijl, Masood Kamali-Moghaddam, Di Wu
Publikováno v:
NeuroMolecular Medicine. 15:458-469
The microtubule-affinity regulating kinase (MARK) family consists of four highly conserved members that have been implicated in phosphorylation of tau protein, causing formation of neurofibrillary tangles in Alzheimer’s disease (AD). Understanding
Publikováno v:
Journal of Internal Medicine. 268:232-245
Blokzijl A, Friedman M, Ponten F, Landegren U (From the Department of Genetics and Pathology, Uppsala University, Uppsala, Sweden). Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine. (Review) J Inte
Autor:
Linda Arngården, Magdalena Mazurkiewicz, Andries Blokzijl, Karin Grannas, Ola Söderberg, Peter Lönn, Agata Zieba
The Hippo pathway plays a crucial role in growth control, proliferation and tumor suppression. Activity of the signaling pathway is associated with cell density sensing and tissue organization. Furthermore, the Hippo pathway helps to coordinate cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a2b5701072f2620cf73bf47792434f
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-268434
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-268434
Autor:
Anna Falk, Annalena Moliner, Urban Lendahl, Camilla Dahlqvist, Eva Reissmann, Carlos F. Ibáñez, Andries Blokzijl
Publikováno v:
The Journal of Cell Biology
The Notch and transforming growth factor-beta (TGF-beta) signaling pathways play critical roles in the control of cell fate during metazoan development. However, mechanisms of cross-talk and signal integration between the two systems are unknown. Her
Publikováno v:
Current Biology. 12:35-45
Background: Members of the GATA family of zinc finger transcription factors are genetically controlled "master" regulators of development in the hematopoietic and nervous systems. Whether GATA factors also serve to integrate epigenetic signals on tar
Publikováno v:
Journal of Biological Chemistry. 276:5140-5146
The signaling capabilities and biological functions of activin receptor-like kinase 7 (ALK7), a type I receptor serine/threonine kinase predominantly expressed in the nervous system, are unknown. We have constructed a cell line derived from the rat p