Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Andriana Lebid"'
Autor:
Ying Zheng, Andriana Lebid, Liam Chung, Juan Fu, Xiaoxu Wang, Andrea Otrocol, Jelani C. Zarif, Hong Yu, Nicolas J. Llosa, Drew M. Pardoll
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTActivins, members of the TGF-beta superfamily, have been isolated and identified in the endocrine system, but have not been substantially investigated in the context of the immune system and endocrine-unrelated cancers. Here, we demonstrated
Externí odkaz:
https://doaj.org/article/3c70e25a6b1c4abc8a3c38e2792d5145
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
YAP is a transcriptional coactivator of the Hippo signaling pathway that has largely been studied for its role in the regulation of organ size during development. Several studies have shown that YAP is upregulated in cancer cells, and more recently i
Externí odkaz:
https://doaj.org/article/dd7f726e95fc49b081623008e9387c13
Autor:
Fan Pan, Duojia Pan, Ling Lu, Drew Pardoll, Huabin Li, Cui-Ping Yang, Paolo Vignali, Xingmei Wu, Xuehong Zhang, Ying Zheng, Ping Wei, Anjali Ramaswamy, Andriana Lebid, Nailing Zhang, Zhiguang Li, Benjamin V. Park, Qian Chen, Joseph Barbi, Jinhui Tao, Xuhao Ni
Supplementary Figure S1. Expression and activation of YAP and other Hippo Pathway factors in CD4+ T cell subsets; Supplementary Figure S2. Characterization of the baseline immune profile of T cell-specific YAP-deficient mice; Supplementary Figure S3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00d43184c0bbed5493b0cab1b26e1fb
https://doi.org/10.1158/2159-8290.22532678.v1
https://doi.org/10.1158/2159-8290.22532678.v1
Autor:
Fan Pan, Duojia Pan, Ling Lu, Drew Pardoll, Huabin Li, Cui-Ping Yang, Paolo Vignali, Xingmei Wu, Xuehong Zhang, Ying Zheng, Ping Wei, Anjali Ramaswamy, Andriana Lebid, Nailing Zhang, Zhiguang Li, Benjamin V. Park, Qian Chen, Joseph Barbi, Jinhui Tao, Xuhao Ni
Regulatory T cells (Treg) are critical for maintaining self-tolerance and immune homeostasis, but their suppressive function can impede effective antitumor immune responses. FOXP3 is a transcription factor expressed in Tregs that is required for thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072fbcee99147b1ccfd961c2ab43a201
https://doi.org/10.1158/2159-8290.c.6546797.v1
https://doi.org/10.1158/2159-8290.c.6546797.v1
Autor:
Nicolas J. Llosa, Drew M. Pardoll, Robert A. Anders, David J. McConkey, Woonyoung Choi, Elizabeth A. Montgomery, Elizabeth D. Thompson, Brian H. Ladle, Christian F. Meyer, Jonathan B. Greer, Fabian M. Johnston, Daniel S. Rhee, Adam Levin, Carol Morris, Andriana Lebid, John A. Ligon, Jessica Swailes, Richard L. Blosser, Ada J. Tam, Gady Cojocaru, Nicholas Siegel, Teniola Oke, Lingling Chen
Supplementary figures. Figures S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3643a31e159931b0878915548e514401
https://doi.org/10.1158/1078-0432.22476588.v1
https://doi.org/10.1158/1078-0432.22476588.v1
Autor:
Nicolas J. Llosa, Drew M. Pardoll, Robert A. Anders, David J. McConkey, Woonyoung Choi, Elizabeth A. Montgomery, Elizabeth D. Thompson, Brian H. Ladle, Christian F. Meyer, Jonathan B. Greer, Fabian M. Johnston, Daniel S. Rhee, Adam Levin, Carol Morris, Andriana Lebid, John A. Ligon, Jessica Swailes, Richard L. Blosser, Ada J. Tam, Gady Cojocaru, Nicholas Siegel, Teniola Oke, Lingling Chen
Purpose:Clinical trials with immune checkpoint inhibition in sarcomas have demonstrated minimal response. Here, we interrogated the tumor microenvironment (TME) of two contrasting soft-tissue sarcomas (STS), rhabdomyosarcomas and undifferentiated ple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c3b189afc50895a7a1a0e4f91ac5d5
https://doi.org/10.1158/1078-0432.c.6529431.v1
https://doi.org/10.1158/1078-0432.c.6529431.v1
Autor:
Nicolas J. Llosa, Drew M. Pardoll, Robert A. Anders, David J. McConkey, Woonyoung Choi, Elizabeth A. Montgomery, Elizabeth D. Thompson, Brian H. Ladle, Christian F. Meyer, Jonathan B. Greer, Fabian M. Johnston, Daniel S. Rhee, Adam Levin, Carol Morris, Andriana Lebid, John A. Ligon, Jessica Swailes, Richard L. Blosser, Ada J. Tam, Gady Cojocaru, Nicholas Siegel, Teniola Oke, Lingling Chen
Supplemental Figures description. S1-S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa67bb053a28c58a8d4613744a4a3d7
https://doi.org/10.1158/1078-0432.22476585.v1
https://doi.org/10.1158/1078-0432.22476585.v1
Autor:
Nicolas J. Llosa, Drew M. Pardoll, Robert A. Anders, David J. McConkey, Woonyoung Choi, Elizabeth A. Montgomery, Elizabeth D. Thompson, Brian H. Ladle, Christian F. Meyer, Jonathan B. Greer, Fabian M. Johnston, Daniel S. Rhee, Adam Levin, Carol Morris, Andriana Lebid, John A. Ligon, Jessica Swailes, Richard L. Blosser, Ada J. Tam, Gady Cojocaru, Nicholas Siegel, Teniola Oke, Lingling Chen
Table components of supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c06020d0711c00ffdb8e6b4f576f81
https://doi.org/10.1158/1078-0432.22476591
https://doi.org/10.1158/1078-0432.22476591
Publikováno v:
The Journal of Immunology. 208:180.09-180.09
Activin signaling molecules and their receptors have not been substantially studied in the context of the immune system and cancer. We show here that tumor-bearing mice had elevated Activins levels, which correlated directly with tumor burden. Likewi
Autor:
Hong Yu, Hiroshi Nishio, Joseph Barbi, Marisa Mitchell-Flack, Paolo Vignali, Ying Zheng, Andriana Lebid, Kwang-Yu Chang, Juan Fu, Lee Blosser, Ada Tam, Drew Pardoll
Publikováno v:
The Journal of Immunology. 208:56.03-56.03
T cell activation and tolerance are tightly regulated to ensure effective elimination of foreign antigen while maintaining immune tolerance to self-antigens. Development of T cell anergy and regulatory T cell (Treg) mediated suppression both contribu